Tag: "incurable" at biology news

Stress hormones may play new role in speeding up cancer growth

...o study nasopharyngeal carcinoma (NPC), a serious, incurable head and neck cancer that occurs most frequently among people of Chinese descent. They treated Glaser's cell line with norepinephrine and, as predicted, the cells all produced MMP-2, MMP-9 and VEGF. This showed that the receptors for this hormone ...

Slow-frozen people? Latest research supports possibility of cyropreservation

... the controversial idea that humans, stricken with incurable diseases, might be frozen and then revived years or decades later when cures are available. Bogdan's experiments involved a form of water termed "glassy water," or low-density amorphous ice (LDA), which is produced by slowly supercooling diluted aq...

UF scientists restore sight to chickens with blinding disease

...e that a similar treatment can be developed for an incurable form of childhood blindness. "We were able to restore function to the photoreceptor cells in the retinas of an avian model of a disease that is one of the more common causes of inherited blindness in human infants," said Sue Semple-Rowland, Ph.D., a...

Mouse mimics chronic leukemia, will aid drug development

... of mice offers the first real animal model for an incurable form of chronic leukemia and should greatly aid the development of new drugs for the disease. The mouse, called the TCL-1 transgenic mouse, develops a malignancy that closely mimics chronic lymphocytic leukemia (CLL). The lack of an animal model h...

Radioactive scorpion venom for fighting cancer

...lly attaches to the cells of a type of essentially incurable brain cancers known as gliomas. Responding to this urgent problem, scientists at the Transmolecular Corporation in Cambridge, Massachusetts created a radioactive version of this scorpion venom. Called TM-601, it contains an artificial version of t...

Genome changes tracked during multiple myeloma initiation, progression and treatment

...pment and progression of multiple myeloma (MM), an incurable malignancy that is the second most common cancer of the blood. The results, published in the April issue of Cancer Cell, provide new genetic and biological insights that open innovative directions for the discovery of effective therapeutics that can ...

U of MN researchers identify ataxia gene

...ered the gene responsible for a type of ataxia, an incurable degenerative brain disease affecting movement and coordination. This is the first neurodegenerative disease shown to be caused by mutations in the protein â-III spectrin which plays an important role in the maintaining the health of nerve cells. The...

Compound from marine bacteria shows potential as multiple myeloma therapy

...ther treatments. Multiple myeloma is a currently incurable cancer of the bone marrow that causes a plunge in the production of vital red and white blood cells. Although relatively rare, it is the second most common type of blood cancer and accounts for 11,000 deaths annually in the United States. Bortezomib,...

Gene therapy works in mice to prevent blindness that strikes boys

...ene to prevent blindness in mice with a form of an incurable eye disease that strikes boys. Writing in the August issue of Molecular Therapy, scientists from the UF Genetics Institute describe how they successfully used gene therapy in mice to treat retinoschisis, a rare genetic disorder that is passed from m...

Most common lung cancers may begin in newly discovered cells

...he adult stem cells to restore defective tissue in incurable fatal chronic lung diseases, such as alveolar cells that are destroyed in emphysema. Or scientists could extract the BASCs, alter their genes, and replace them in a kind of cellular gene therapy for genetic diseases such a cystic fibrosis. "This wor...

Genetic links could unlock clues to leading cause of blindness

...the dark about many of the factors that cause this incurable disease. But new insight from University of Florida and German researchers bout a genetic link between rhesus monkeys with macular degeneration and humans could unlock secrets about the earliest stages of the disease, when severe vision loss could s...

Gov't Creates Gene Database of Normal Human Tissues

...ntists find new targets in the cells of previously incurable cancers. The driving force of research in our section is to translate genomic information to the clinic. The goal is to save lives and improve the quality of life for children with high-risk cancer." Until now, no publicly available, normal human or...

'Smart drug' targets deadly brain cancer

...) reports that a new "smart" drug treatment for an incurable form of recurrent brain cancer slowed tumor growth in more than one-third of the 65 adult patients who tried it. The same research team also developed a screening technique to help predict which patients will respond best to this treatment. Mayo res...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

... silencing as a potential therapy, particularly in incurable progressive neurological diseases such as ALS. "I would not be surprised to see, in the next ten years, this technology used for treating diseases of the nervous system, particularly diseases that involve toxic gain-of-function, such as inherited for...

New Treatment Rivals Chemotherapy For Lymphoma, Study Finds

...follicular lymphoma ?a cancer generally considered incurable ?who had not been previously treated with any other form of therapy received a single course of treatment with the Bexxar therapeutic regimen, a radioactive antibody injected into the bloodstream that targets and kills cancer cells. Of the 76 patient...

The very unexpected life and death of a leukemic cell

B cell chronic lymphocytic leukemia (CLL) is an incurable disease in which cells in the bone marrow grow and survive to the point where they become abnormal and malignant (leukemic). The progression of the disease is slow and there has been a lack of information regarding the rate of production of CLL cells...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...ld may alter the natural history of this currently incurable leukemia," he added. A decade ago, CLL was considered a uniform disease of immature white blood cells that didn't die, with the slow rise in leukemia cell count seen in patients due to an accumulation of these immature and incompetent white blood ce...

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