Driver of anthrax toxicity could lead to late-stage therapy
...ax protection afforded by the antibodies rose with increasing dose. Anthrax is a lethal disease of humans and other animals caused by the spore-forming bacteria Bacillus anthracis, which has been the focus of biological interest and bioterrorism concern. The virulence of the bacteria depends on separate comple...World faces challenge as life expectancies lengthen, scientist says
...e that is five times faster than the current rate, increasing the modal age of death in industrialized countries such as the United States from roughly 80 years to 100. "We studied different countries around the world that are representative of different situations and took a look at where they'd end up," Tulj...Hooked on fishing, and we're heading for the bottom, says scientist
...luding Science and Nature. "We're in a phase where increasing fishing effort produces less catch." While global catches peaked in the late 1980s, the peak occurred earlier in those parts of the world where industrial fishing developed first. Thus, peak fish occurred in the mid-1970s in the North Atlantic, expl...CU, USDA team to curb two invasive, poisonous vines
...if that is not enough, the plants are growing with increasing vigor in some maize and soybean fields and are altering forest regeneration patterns. Native populations of pale swallow-wort ( Vincetoxicum rossicum ) in Ukraine and black swallow-wort ( V. nigrum ) in southwestern Europe are kept in check, though,...The Amazon in 2050: Implementing the law could save a million square kilometers of rainforest
...lose most of the forest cover in their catchments, increasing flooding and sedimentation. The region of greatest loss of mammals will be in the eastern Amazon, where expanding agriculture will overrun many species with small ranges. Of the major highways planned for paving, the Manaus-Porto Velho highway will b...Researchers use dirt to stay one step ahead of antibiotic resistance
... antibiotics. Antibiotic resistance has become an increasing public health concern because the organisms that cause infections in humans and animals are becoming less receptive to the healing aspect of antibiotic drugs. The team led by professor Gerry Wright, chair of Biochemistry and Biomedical Sciences of t...Manipulating single cell receptor alters animal behavior
...iven this drug increased their salt intake without increasing their water intake. "This supports our hypothesis that intracellular signaling pathways stimulated by the activation of angiotensin receptors can be separated based on behavioral relevance," he says, "something that had not been shown before." "Und...World's pledge to halve hunger by 2015 looks like empty promise
...lth care," he says. Policies should also focus on increasing farm incomes in rural areas in low-income countries, as well as on generating non-agricultural employment, particularly in urban areas, to absorb rural migration. ...Lack of a key enzyme dramatically increases resistance to sepsis
... production of several pro-inflammatory cytokines, increasing vulnerability to bacterial infection and septic mortality. "Without the experimental model of peritonitis perfected by John Mathison from Scripps Research, we would not have been able to differentiate between the two mouse phenotypes," Ulevitch sa...Cholesterol gets 'thumbs up' for role in digit development
...e site of its production and then tapered off with increasing distance from the synthesis site. But previous studies in mice suggested that cholesterol promoted the movement of Sonic hedgehog, a counterintuitive proposal given cholesterol's supposed tethering ability. To try and clear up cholesterol's role ...Virginia Tech helping to develop higher quality, disease-resistant wheat varieties
...etter end use quality, which are all essential for increasing competitiveness of U.S. wheat in global markets." Griffey, along with other researchers from Virginia, Kentucky, Maryland, and North Carolina, will be specifically looking at wheat traits of critical importance in the Mid-Atlantic region where disea...Fertility drugs given 'all-clear' in new study
...ed be used in the treatment of infertility without increasing risk to the fetus." The study contradicts an earlier, much smaller study linking letrozole to increased rates of inherited malformations. This study led to widespread concern about the use of letrozole, a drug which has been widely used in the treat...Botox could help target resistant tumors for treatment
... care, tumor cells of most cancer types have shown increasing resistance to therapies. This phenomenon has resulted in more toxic dosages of chemotherapy and radiation, and increased efforts to develop more drugs to which tumors don't show resistance. To increase the efficacy of anti-cancer treatments, the new ...Common practices at petting zoos put visitors at risk
... found to protect against infection. "There is an increasing incidence of reported outbreaks of illness associated with petting zoos over the years. People need to be aware of these risks and take the appropriate precautions such as washing their hands after visiting," says Fred Angulo of the Centers for Dise...Forsyth scientists gain greater understanding of how embryos differentiate left from right
...tificially equalizing the asymmetry in H+ flux, by increasing or decreasing it on both sides equally, both randomized the location of the viscera without causing any other defects. To understand the mechanism of action of H+-V-ATPase, researchers isolated its two physiological functions, cytoplasmic pH and memb...Team discovers possible 'universal strategy' to combat addiction
...vered that PTEN acts on these serotonin receptors, increasing brain cell activity. This is the same "reward" process sparked by drugs of abuse. Armed with this knowledge, the team designed a molecule called a peptide, tailored to fit the serotonin receptors and block PTEN. When rats were treated with this PTEN...Avian influenza virus in mammals spreads beyond the site of infection to other organ systems
...lso from the digestive and urinary tracts, greatly increasing the possible routes of mammalian transmission. Systemic disease has long been known to occur in birds, with the fecal-oral route of transmission being most important. However, this is the first demonstration of systemic replication in cats, providi...Carbon cycle was already disrupted millions of years ago
... The atmospheric carbon dioxide concentration is increasing as a consequence of the large-scale use of fossil fuels in the industrial era. This has apparently brought about a stronger relative increase in the light carbon isotope 12C. Due to this the ratio of the stable carbon isotopes 13C/12C has show a clea...Extinctions linked to climate change
... greenhouse warming and other climate changes were increasing the frequency and intensity of El Nino events, whi...life cycle in one year, instead of two, leading to increasing problems with the fungus they carry. "When pathogens such as this can spread more rapidly, they can ...... of individual well-being, and are even capable of increasing creative thought and output in workplace settings," Nell said. "If we can help make floral products last longer, their value to consumers will be greater." He expects that with improvements to rose quality and longevity, people will buy flowers mor...