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Tag: "increasing" at biology news

Scientists develop a way to make the deadliest toxin known even more toxic

... bind to specific sites on the neurotoxin protein, increasing protease activity and enhancing the toxin's effect...od for minimizing dosage, reducing resistance, and increasing its clinical efficacy." Botulinum neurotoxins are the most lethal poisons known. They produce progr...

Cracking the genetic code for control of gene expression

...s amino acids, we can make sense of the constantly increasing amout of DNA sequence data as far as it encodes proteins. This code was solved in 1966 and it has allowed researchers to find new genes and estimate the total number of genes in the human genome. However, coding sequence covers only about 1.2% of the...

How marine reserves are giving coral reefs a helping hand

...iences at the University of Exeter,said: "While an increasing number of larger predators is essentially good news we had concerns that this might result in a decrease in the numbers of parrotfish, which could ultimately damage the health of the reef. More than 20 years ago sea urchins in the Caribbean were wipe...

Removing DNA repair gene causes metabolic syndrome

...amine ways to delay the onset of symptoms, such as increasing the expression of the NEIL1 gene or dampening oxidative stress to the cells that damages their DNA. Such techniques could one day become therapies. "One may be able to develop a diagnostic method to do early screening," Lloyd said. "Or there could b...

Access to antiretrovirals unlikely to reduce HIV infection rates

...d compare the impacts of alternative strategies of increasing ART access in resource-poor countries. Some of the strategies included the provision of diagnostic laboratories that could routinely measure CD4 counts and viral loads of HIV-infected individuals (only if this is done could people be treated before t...

Scientists re-engineer a well-known antibiotic to counter drug resistance

...a by inhibiting cell wall synthesis, significantly increasing the drug's spectrum of activity. In recent years, a number of the most common strains of enterococci have become resistant to vancomycin and use of the antibiotic has been under scrutiny. This re-engineering effort could help make the drug more effec...

New study reveals promising osteoporosis treatment

...eatments also have serious side effects, including increasing the risk of heart disease, strokes, and breast cancer. But the supplement Dr. LeGeros developed by combining magnesium (Mg), zinc (Zn), and fluoride (F) ions in a calcium-phosphate (CaP) matrix does not have the side effects of the current pharmaceu...

Most human-chimp differences due to gene regulation ?not genes

...latory network can change with very few mutations, increasing the impact and minimizing the risk. "The big question," he said, "is why are humans so different? What sort of changes in the environment or lifestyle would drive such a rapid shift in the expression of genes -- in this case in the liver -- in human...

Efficiency, not more doctors, is the prescription for aging population

...man and his team write, efforts should be aimed at increasing the efficiency of medical practice and directing resources to care that has been proven to be effective. They point to large interdisciplinary (or multispecialty) group practices, a structure that has been in place in many parts of the United States...

New licensing agreement to maximize AIDS drug development

...n in women are in sub-Saharan Africa and rates are increasing in women in South and Southeast Asia. CONRAD has been involved in the research of nearly every microbicide currently in clinical trials. They are currently managing a second Phase III trial of a microbicide called Ushercell in Uganda and South Afric...

Loosen leash on cancer protein 'watchdog,' researchers say

...e were created to answer a twofold question: Could increasing their levels of p53 delay or prevent tumor formation in living creatures, and would there be any negative consequences to the increase? "We were primarily interested in the second part of the question when we began," Mendrysa said. "These mice had a...

Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections

...n their research in response to observations about increasing number of community-acquired skin and soft tissue infections that were due to MRSA. Dr. Blumberg notes, "In recent years there have been reports of outbreaks of community-acquired infections due to MRSA. Our study now shows that these community-acq...

New Research Shows Artificial Light at Night Stimulates Breast Cancer Growth in Laboratory Mice

...S?grants division. “These results suggest that the increasing nighttime use of electric lighting, both at home and in the workplace, may be a significant factor.?/p> Previous research showed that artificial light suppresses the brain’s production of melatonin, a hormone that helps to regulate a person’s sle...

Molecular force field helps cancer cells defend against attack

...al." Focal adhesion kinase, or FAK, is commanding increasing attention and has spawned a flurry of research designed to develop new drug therapies, said Cance, who is known internationally for his genetic investigations of tumor survival. These medicines would prevent FAK from linking with the protein known as...

Illegal trade is propelling rare turtle toward extinction, new report

...les are still in high demand. "We hope that by increasing awareness and enforcement capacity of these agencies, poachers will find it increasingly difficult to smuggle out any of the turtles that remain on Roti Island," said Chris Shepherd from TRAFFIC Southeast Asia and the co-author of the report. In 200...

Biofuels can replace about 30 percent of fuel needs with significant research and policy effort

... a comprehensive research and policy plan aimed at increasing the practicality of using biofuels and biomaterials as a supplement to petroleum. The review article, called "The Path Forward for Biofuels and Biomaterials," appears in the Jan. 27 issue of Science. "We can readily address, with research, 30 percen...

Salmonella bacteria use RNA to assess and adjust magnesium levels

...ally modifies phoP. The changed phoP binds to DNA, increasing the number of times instructions for making MgtA and over 100 other proteins are copied from DNA. But when Salmonella encounters a high-magnesium environment, phoQ deactivates phoP, and fewer copies of the instructions for making MgtA are made. Whe...

Use of amino acid supplement following a heart attack provides no benefit, may be harmful

...gs have broad public health implications given the increasing availability and use of L-arginine in patients with and without established cardiovascular diseases." Death occurred in 6 patients (8.6 percent) in the L-arginine group died during the 6-month study period vs. none in the placebo group. "In conclu...

Little known DNA repair enzyme may be a tumor suppressor gene

...gs have broad public health implications given the increasing availability and use of L-arginine in patients with and without established cardiovascular diseases." Death occurred in 6 patients (8.6 percent) in the L-arginine group died during the 6-month study period vs. none in the placebo group. "In conclu...

An elephant tail

...gs have broad public health implications given the increasing availability and use of L-arginine in patients with and without established cardiovascular diseases." Death occurred in 6 patients (8.6 percent) in the L-arginine group died during the 6-month study period vs. none in the placebo group. "In conclu...

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