Mice with glowing hearts shed light on how hearts develop
...igned molecule that fluoresces when calcium, which increases dramatically with each muscle contraction, is released in heart cells. Co-author Junichi Nakai of the RIKEN Brain Science Institute in Wako-shi, Japan, developed the fluorescent molecule by modifying a green fluorescent protein (derived from biolumin...Hopkins researchers discover genetic switch that turns off an oxygen-poor cell's combustion engine
...oduction of an energy-rich molecule called ATP and increases production of toxic molecules. ATP supplies energy the cell needs to perform each of its many chemical reactions and tasks, and in this way acts as the "currency" for the cell's energy economy. A report on the work, done with mouse cells genet...Gene variation increases SIDS risk in African Americans
...deaths result from a common genetic variation that increases an infant's risk of developing an abnormal heart rhythm during times of environmental stress, a research team based at the University of Chicago reports in the February 2006 issue of the Journal of Clinical Investigation. Children with two copies o...Data published in PNAS show antibodies can be made 10 times more toxic to cancer cells
...ng the "Fc" region of monoclonal antibodies (mAbs) increases their toxicity to cancer cells, potentially improving the utility of targeted cancer therapies, according to research conducted at Xencor, which will be published in the March 14 print issue of the Proceedings of the National Academy of Sciences (PNA...Man's best friend: Study shows lonely seniors prefer playtime with pooch over human interaction
...hought that the dog acts as a social lubricant and increases the interaction between the residents. We expected the group dog visits were going to work better, but they didn't. "The residents found a little quiet time with the pooch is a lot nicer than spending time with a dog and other people," he said. Th...HIV decline in Zimbabwe linked to behavioural change
...s also a delay in the onset of sexual activity and increases in condom use prior to the time of the study may also have contributed". The study found that among 17 to 19 year old men, only 27 percent had commenced sexual activity in the later census, compared with 45 percent in the earlier one. For women aged...Genes affecting blood pressure change as children become adults
...o identify some genes that may influence unhealthy increases in blood pressure that occur over time. A second finding that bears further study is that the importance of non-shared environmental influences became more important in the black twins over the four-year period, says Dr. Snieder. Non-shared influen...Possible brain hormone may unlock mystery of hibernation
...eports evidence that the level of HPc in the brain increases at the onset of hibernation independently of changes in body temperature. Moreover, treatments that block HP activity in the animals' brains cuts hibernation short. "One of the most curious biological phenomena in mammals is their ability to hiberna...Chocolate milk could be key to longer, healthier life
...ming proteins and sugars after resistance training increases the synthesis of proteins used for force i.e. it builds muscles. Dr Miller's research will tell us whether doing the same after aerobic exercise can also increase the synthesis of mitochondrial proteins which affect our ability to make energy and pla...Weighting cancer drugs to make them hit tumors harder
... the drug by adding a "macromolecular weight" that increases its concentration and staying power inside the tumor. The heavier molecules are more selectively absorbed by tumors because tumor blood vessels are more permeable or "leakier" than normal blood vessels. Thus, larger molecules can pass through the tum...Albatross study shows regional differences in ocean contamination
...cted by previous researchers in 1991 and 1992. The increases were much greater in black-footed albatrosses than...to be released into the marine environment. "The increases we saw compared with ten years ago probably reflect the ongoing use of these chemicals in countries ...Vegetables inhibit growth of prostate cancer in mice with human tumors
...cted by previous researchers in 1991 and 1992. The increases were much greater in black-footed albatrosses than...to be released into the marine environment. "The increases we saw compared with ten years ago probably reflect the ongoing use of these chemicals in countries ...Alaska seal pup diet may hold key to decline of population
...response to a stressor that dilates the pupils and increases heart beat. Animals in the low fat group may take a longer time to recover. Comparing their data with observations and tests on seals in the wild done by the Alaska Department of Fish and Game. ...Researches discover gene critical for protection against septic-shock-induced death
.... Mortality due to sepsis is around 30 percent and increases with age from 10 percent in children to 40 percent in the elderly. Mortality is 50 percent or greater in patients with the more severe syndrome, septic shock. Suspecting that a dysregulation in the body's inflammatory response exacerbates sepsis, th...Taking evolution's temperature: Researchers pinpoint the energy it takes to make a species
...d structure of plankton in the tropics and that it increases exponentially because of temperature," said James Gillooly, Ph.D., an assistant professor of zoology with the UF Genetics Institute. "It tells us something about the fundamental mechanisms that shape biodiversity on the planet." Speciation - when an...Cincinnati surgeons report new treatment for often-fatal injury
...ficant stress on the patient's heart and brain and increases the risk for heart attack, bleeding, paraplegia and other problems. J. Keith Thompson, DO, and Amy Reed, MD, both of UC, were coauthors on this study. ...New MRI technique shows emphysema in asymptomatic smokers
...e of the airspaces in the lungs. Because emphysema increases airspace size, the ADC map shows the location and severity of the disease. "The ADC maps are very sensitive to changes in the lung structure," Dr. Fain said. "With this tool, it was shown that even smokers that appear healthy have enlarged lung airs...Mosquito spray increases toxicity of pyrethroids in creek, study finds
...ty, but it is a chemical synergist, which means it increases the toxicity of other chemicals such as pyrethrin and its synthetic counterpart, pyrethroid. "PBO shuts down the enzyme that animals use to detoxify pyrethrin, so it gives pyrethrin more punch," said Weston. "Without PBO, you'd need a greater conce...One-third of adults with diabetes still don't know they have it
...t fast is high but not yet diagnostic of diabetes, increases the risk of heart disease as well as the risk of developing type 2 diabetes. "It's important to know if you have pre-diabetes or undiagnosed type 2 diabetes," said Dr. Larry Blonde, chair of the National Diabetes Education Program (NDEP), jointly ...Mice lacking key immune component still control chronic viral infections
...ion with gamma herpes viruses such as EBV and KSHV increases the risk of some cancers, especially in persons with weakened immune systems. Immune system cells known as CD8 or cytotoxic T cells are responsible for recognizing virus-infected cells and killing them or sounding alarms that summon other defensive...