Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
... blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, report that the harmful effects of saturated and trans fats are set in motion by a biochemical switch, or co-activator, in liver ...Growth in the sea comes down to a struggle for iron
...powerful greenhouse gas, he suggested that natural increases in iron inputs to the oceans during the geologic past may have removed enough carbon from the atmosphere to affect global climate, perhaps even contributing to the onset of ice ages. Martin died in 1993 just as tests of his ideas were getting underwa...The secret to longevity in tubeworms
...n a colony of 1,000 individuals; with it, survival increases to over 250 years, matching the longevity of actual living tubeworms. To date, the proposed return of sulfate to the sediments through the roots is only a hypothesis--albeit one with much to support it--that still awaits direct confirmation. By prov...Scientists detect probable genetic cause of some Parkinson's disease cases
...h chronic and progressive. Incidence of thedisease increases with age, with an average onset at about 60 years....Nanogen Issued Patent for Electronic Microarray With Memory
...ol of the biological molecules during analysis and increases data management efficiency by tracking test site activation and array usage directly on the electronic microarray cartridge. "This addition to our growing intellectual property portfolio illustrates our ability to develop differentiated advanced dia...Alcohol's effects on gene expression in the central nervous system
...The stimulation of VTA dopamine neurons by alcohol increases the expression of genes involved in the synthesis of synaptic proteins in target regions of the VTA. In short, these results suggest that alcohol can produce changes in the brain reward system that can further increase the rewarding effects of alcoho...Zebrafish may hold key to understanding human nerve cell development
...f humans that make hearing possible. This research increases ourunderstanding of how nerve cells develop and whether it may be possibleto regenerate these types of cells in humans one day," said TatjanaPiotrowski, Ph.D., assistant professor of neurobiology and anatomy atthe University of Utah School of Medicin...Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined
...f humans that make hearing possible. This research increases ourunderstanding of how nerve cells develop and whether it may be possibleto regenerate these types of cells in humans one day," said TatjanaPiotrowski, Ph.D., assistant professor of neurobiology and anatomy atthe University of Utah School of Medicin......f humans that make hearing possible. This research increases ourunderstanding of how nerve cells develop and whether it may be possibleto regenerate these types of cells in humans one day," said TatjanaPiotrowski, Ph.D., assistant professor of neurobiology and anatomy atthe University of Utah School of Medicin...TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
...oma by enlarging the B lymphocyte population. This increases the likelihood that at least a few of the cells acquire a mutation eliminating p53 function just by chance. In the absence of p53, the cells remains alive and become cancerous." The study's findings help explain the interlocking roles of MYC, TEL2, ...How an AIDS-Related Cancer Unleashes Inflammation
...ynthesize, said Ganem. The activation of MK2 also increases production of blood-vessel-forming, or angiogenic ... the regulatory protein p38. p38, in turn, further increases activation of MK2. "We still don't know the mechanism by which kaposin B activates MK2," said Ganem...Opposing fat metabolism pathways triggered by a single gene
...s, nhr-49 sets in motion two opposing pathways: it increases expression of a gene acs-2, which leads to reduction of fat content, and it increases expression of another gene fat-7, which, by reducing acs-2, increases fat content. In its function, ...Special Imaging Study Shows Failing Hearts Are 'Energy Starved'
...mine whether increased energy demand during stress increases the rate of ATP synthesis through CK. Then, 17 patients with histories of heart failure were similarly tested to measure the CK flux. Results showed that CK flux in healthy hearts is adequate to supply energy to the heart over a fairly wide normal ...Sexual cooperation: Mating increases longevity in ant queens
...zed prior to mating. It remains unknown how mating increases the longevity of the females. Sexual cooperation, rather than sexual conflict, is promoted by the life history of social insects; whereas most insect females undergo repeated phases of mating and reproduction throughout their lifetime, ant queens in...Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy
... shows that the CpG 7909 DNA sequence is safe, and increases the immune system's ability to recognize and destroy cancer cells. The Phase I study was conducted by the Lausanne Branch of the Ludwig Institute for Cancer Research (LICR) at the Lausanne University Hospital in Switzerland, in the framework of the i...US life expectancy about to decline, researchers say
...out human life expectancy, which assumes that past increases will continue indefinitely. Most forecasts of life...e and because they have experienced the most rapid increases in obesity in recent years, according to the authors. It is well documented that obesity is associa...Scientists discuss improved biopesticides for locust control in West Africa
...pecifically a lignin coating for the spores, which increases their resistance to ultraviolet radiation." Research at Virginia Tech demonstrated UV resistance 15 times greater for coated spores as compared to non-coated spores. "This technology is applicable to many other biopesticides and should make them more...Drug-resistant bacteria on poultry products differ by brand
...tion. Claims have been made that using antibiotics increases food safety by reducing pathogens on the meat. Interestingly, in addition to the results regarding fluoroquinolone-resistant Campylobacter, we also found that brands that do not use any antibiotics during production were no more likely to contain Cam...Live fast, die young true for forests too
... heat-trapping gas implicated in climatic warming, increases as carbon storage in forests decreases, and decreases as carbon storage in forests increases. Information regarding such potential changes is therefore needed to reduce uncertainties in predicting future climatic changes. ......ious studies by Dr. Li have shown that pulsed-HIFU increases the uptake of drugs. Now we've shown that it works for genes and we're making the case that there's a connection between the two." Other methods currently being investigated for enhancing gene delivery, such as lasers and electric current, are limit...