Marburg haemorrhagic fever in Angola update
...with outbreaks of other viral haemorrhagic fevers, including Ebola, outbreaks of Marburg can be brought to an e... health care facilities. Weakened infrastructures, including those for communications and transportation, are another problem. Yesterday, the WHO office in Uige ...Researchers rein in regulatory RNAs
...n implicated in various stages of gene regulation, including transcription, mRNA processing, splicing, stability, transport, and translation. Various examples of such overlapping genes have been documented in all life forms ?from viruses and prokaryotes to plants and animals. To date, most studies on SAT pair...New drug shows promise as powerful anticancer agent
... cell division in a variety of human cancer cells, including cells that are notoriously resistant to commonly u...ficantly inhibited a wide variety of human tumors, including liver, breast, and pancreatic cancers that were grown in mice. ON01910 was also highly effective and...Microbial forensics: The next great forensic challenge
...ts point to many challenges posed by bioterrorism, including that numerous pathogens exist in nature and do not necessarily require sophisticated expertise or technology to be weaponized; many methods could be used by adversaries to perpetrate an attack, from simple to complex; physicians may not diagnose earl...Anti cancer virotherapy well tolerated in first human administration, research finds
...therapies for different hard to treat malignancies including melanoma and ovarian cancer. These viruses occur naturally and routinely in the community causing mild infections in adult humans. Previously the Shafren group has published research on CVA21 that showed success in specifically targeting and killin...Chemicals in tattoo inks need closer scrutiny
... that tattoo inks cause adverse effects in people, including allergic reactions to ink components, a burning sensation during the course of MRIs, and the migration of inks to different tissues in the body, such as the lungs. It is unclear, however, what the specific causes of these reactions might be, and the...Researchers uncover sequence of major rice pathogen
...odes a large and diverse set of secreted proteins, including those defined by unusual carbohydrate-binding domains. This fungus also possesses an expanded family of G-protein-coupled receptors, several new virulence-associated genes, and large suites of enzymes involved in secondary metabolism. Consistent with...Reservoirs may accelerate the spread of invasive aquatic species, researchers say
...e benefited from the use of reservoirs as avenues, including Daphnia lumholtzi, a water flea from the Old World tropics, and the copepod Eurytemora affinis. Some evidence indicates that the spread of zebra mussels, an economically important invasive species, may also have made use of reservoirs to spread. Have...First frozen egg baby born in Canada
...ed from vitrified eggs, resulting in 7 pregnancies including this livebirth. "The results are particularly encouraging because this success rate is comparable to regular IVF cycles with ICSI using fresh eggs in many IVF centres," says Dr. Tan. Egg freezing is useful for a number of reasons. "The process enabl...Scientists identify genetic pathways essential to RNA interference
...may be involved with the regulation of DNA itself, including the repair of DNA damage. "These new steps indicate there is more to RNAi than RNA destruction," says Kim. "And the connection to DNA damage pathways, which was totally unexpected, suggests a potential connection between RNAi and the control of cell ......he non-steroidal anti-inflammatory class of drugs, including COX-2 selective and prescription and non-prescript...ctions are based on the available scientific data, including data accumulated since the drugs were approved. The FDA has carefully considered the presentations, ...Small species back-up giant marsupial climate change extinction claim
...s and small mammals to giant wombats and kangaroos including many species previously unknown to have occurred in the Darling Downs fossil record. The results suggest that the extinction of Darling Downs megafauna was caused by a massive shift in climate rather than by the arrival of humans who over hunted ani......tional charities don’t even list chronic diseases, including cancer, as health priorities on their agendas.?/p> The increasing pediatric cancer death rate in countries with limited resources is especially tragic because strategies exist that could be used to ensure wider access to effective cancer treatmen...Same-Sex Mating Discovered in a Toxic Fungus
...ow Xiaorong Lin, Ph.D., also of Duke. "Organisms, including fungi, usually exist in an approximately one-to-on... strains lacking components required for mating -- including pheromones, pheromone receptors and other genes with known roles in mating -- exhibited a defect in ...Test for early detection of prostate cancer shows promise
... and then measured the EPCA levels in 46 patients, including those with prostate cancer (12 patients), bladder cancer (six patients), colon cancer (two patients), kidney cancer (one patient), spinal cord injury (seven patients) and noncancerous prostate inflammation (two patients), and 16 healthy individuals. ...Used in a new way, RNA interference permanently silences key breast cancer gene
...lved in the formation of multiple types of tumors, including breast cancer. When hijacked by a cancer cell, the activated gene is believed to interfere with the ability of key immune cells to attack a growing tumor. Investigators used the lentivirus to permanently insert the RNAi into the genome of the cancer...Bioelectronic ‘signatures?hold key to DNA mutations
...wrote 660 papers and has 12 patents to his credit, including involvement in the development of the first noninvasive biosensor for diabetes, the FDA approved Gluco Watch, which monitors glucose levels through human sweat. “The ultimate goal is to make something similar to a hand-held glucose monitor for futur...New understanding of DNA repair may pave way to cancer treatments
...cess that prevents formation of genetic mutations, including those that lead to cancer. "This is the first time we've seen a protein which has been implicated in gene regulation possess an independent function--in DNA repair--while both functions are uncoupled from one another," said Ronai. Dr. Ronai's labora...Duke engineers develop new 3-D cardiac imaging probe
...laboratory tests on animals." Smith and his team, including biomedical engineering graduate student Chris Pua, developed the probe specifically for use in hospitals and clinics. For example, they used the outer casing of a commercially available 2-D TEE probe to house their new 3-D model. The casing design al...Scientists journey to southern Africa to unravel the secret world of elephant communication
... seismic communication is common in small animals, including spiders, scorpions, insects and a few vertebrate species, such as white-lipped frogs, kangaroo rats and golden moles. Seismic sensitivity also has been observed in elephant seals--huge marine mammals not related to elephants. But O'Connell-Rodwell w...