New polysaccharide may help combat multidrug resistance in cancer
... reverse the malignant properties of cancer cells, including proliferation, invasiveness, and drug resistance," explains Dr. Toole. "Hyaluronan oligomers are non-toxic, non-immunogenic, and readily applicable to several proliferative disease processes, especially cancer. We are hoping that hyaluronan antagonis...Researchers develop assay that could be applied to drug screening
...undamental importance for many cellular activities including receptor down-regulation, nutrient uptake and main...inery of CME has been co-opted by several viruses, including rabies, as a means of entry into healthy cells. The researchers led by David Zenisek, assistant pro...Researchers find new giant amphibian fossils in Africa
...ng amphibians have been discovered by researchers, including investigators from McGill University. Their findings published in today's issue of Nature, describe the first and oldest amphibious carnivores from the Republic of Niger in West Africa. "This the first evidence of carnivores in this area," says McGi...Brain May Be Less Plastic Than Hoped
... at Massachusetts General Hospital, and colleagues including Nikos K. Logothetis of the Max Planck Institute for Biological Cybernetics used functional magnetic resonance imaging (fMRI) to monitor cortical activity for seven and one-half months after injury to the retina of adult monkeys. They found limited re...wFleaBase: the Daphnia genome database
...f Daphnia pulex will be integrated into wFleaBase, including gene predictions and ortholog assignments based on sequence similarities with eukaryote genes of known function. wFleaBase aims to serve a large ecological and evolutionary research community. Our challenge is to rapidly expand its content and to ult...A New Species of Monkey is Discovered in Tanzania: The First in Africa for More Than 20 Years
...oted by Davenport, the Southern Highlands forests, including those of Mt Rungwe and Kitulo, are severely degraded by illegal logging, and without prompt action the animal’s future is in jeopardy. On the other hand, the Ndundulu Forest Reserve is in good condition, but there is concern that the population of t...Stealth Worms May Improve Insect Pest Control
...ennia. EPNs are found in terrestrial environments, including deserts, rainforests, grasslands and other ecologi...ction) techniques and through molecular screening, including PCR (polymerase chain reaction) and DNA sequence analysis. The researchers determine the nematode's...Scientists generate patient-specific stem cells, Science study says
...l oversight and ethical issues in oocyte donation, including the need to promote realistic expectations of the outcomes of stem cell research. The Korean researchers who performed this stem cell research improved upon their protocols that yielded the first embryonic stem cell line from a cloned human blastocy...SuperLigands - a database of ligand structures derived from the Protein Data Bank
...l oversight and ethical issues in oocyte donation, including the need to promote realistic expectations of the outcomes of stem cell research. The Korean researchers who performed this stem cell research improved upon their protocols that yielded the first embryonic stem cell line from a cloned human blastocy......mbers, a reptile heart has only one. "In mammals, including humans, a 10-30 percent increase in ventricular ma...emodeling and ventricular growth in other animals, including humans. Hicks' research is supported by the Integrative Organismal Biology program at the National ...Mouse with designer liver has enhanced glucose tolerance, insulin response
...cer. Today the Burnham Institute employs over 700, including more than 550 scientists. The majority of the Institute’s funding derives from federal sources, but private philanthropic support is essential to continuing bold and innovative research. ...Bobbing birds do it for a reason
...al for high-quality vision in birds; many animals, including humans, stabilize visual fields only transiently, through the use of eye movements alone, and accept quite a lot of so-called "visual flow" when in motion. In new work addressing this question, Thomas Cronin and Matthew Kinloch at the University of ...AIDS Public Awareness Campaign Expands Following Report Of Rapidly Progressive HIV
...ther potential responses to the current situation, including examining ways to better monitor HIV drug-resistan...s television promotions with national celebrities, including Alicia Keys. The initiatives announced today build on the public awareness efforts now underway in ...Nature provides inspiration for important new adhesive
...de fumes are associated with some health problems, including eye and throat irritation. The chemical has been shown to be a human carcinogen, and in some circumstances it may be a concern in some residential building products. The other key advantage of the new adhesives is their superior strength and water r...To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists
...th the ability to resist antibiotics have emerged, including those that cause TB, pneumonia, cholera, typhoid, salmonella, and staphylococcal dysentery. These diseases are coming back resistant to the antibiotics that have been used to treat them, and people infected with these resistant strains have to be tre...Radio-tracking associated with 'dramatic shift' in water vole sex ratio
...essed and malnourished females of various species, including water voles. The ecologists suggest this could be explained in terms of the local resource competition hypothesis, which predicts that mothers with access to poor resources will produce offspring of the sex most likely to disperse and therefore reduc...Cousin of Asian super termite invades Florida
...rols the Formosan and other subterranean termites, including the new Asian termite. His bait system has a chemical called noviflumuron, a growth regulator that prevents termites from molting, thereby reducing the ability of the worker population to sustain underground colonies. The chemical has a low toxicity ...WHO suspends Marburg work, appeals for new funds
...taff and essential supplies for infection control, including disinfectants. Additional activities that urgently need to be strengthened include the early detection and isolation of cases and the tracing and follow up of contacts. ...... detect and identify these disease-causing agents, including proteomic and genomic analysis as a gateway to better diagnostics, therapeutics, vaccinations, genotyping, and forensics. ...