Tamoxifen for breast cancer prevention does not benefit most women
...cers. In addition, it has been shown to reduce the incidence of invasive breast cancer among high-risk women by up to 49 percent. However, tamoxifen is associated with significant adverse effects, including cataracts requiring surgery, deep vein thromboses, endometrial cancer and stroke. Women taking tamoxif...Matrilin-3 gene discovered to prevent onset of osteoarthritis
...ED. The mice lacking matrilin-3 developed a higher incidence of osteoarthritis in adulthood without developing deformities in childhood. The results challenge one theory of osteoarthritis ?that the disease is caused by degeneration from an abnormal skeletal structure. "Our study shows that even in those n...Selenium-protein deficiency raises prostate cancer risk
...eins, has been shown in many studies to reduce the incidence of cancers -- notably lung, colorectal and prostate. "The problem is, nobody seems to know how the mechanism works, and that's not trivial," said Alan Diamond, professor of human nutrition at the University of Illinois at Chicago and principal inves...Study finds that a woman's chances of having twins can be modified by diet
...in vitro fertilization (IVF) methods increases the incidence of monozygotic twinning -- where the transfer and/or implantation of two embryos results in three infants -- and he proposed that adding more calcium or reducing the chelating agent ethylenediamine tetraacetic acid (EDTA) in the IVF incubation media ...Viral hitchhiker inhibits Wolbachia bacteria's ability to proliferate
...n Wolbachia cells, the WO-B virus might reduce the incidence of cytoplasmic incompatibility in a host, not promote it. Using DNA analysis and electron microscopy, the scientists quantified the number of WO-B viruses and Wolbachia cells in the testes of a common host: the fruit-fly-sized jewel wasp, Nasonia v...Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
...nd the liposome with chemotherapy also reduced the incidence of cancer by between 20 and 50 percent in all tested cancer lines. In addition to its anti-tumor effect, the researchers found that the therapeutic liposome attacked the tumor's blood supply, especially when combined with chemotherapy. By inducing...Wild vs. lab rodent comparison supports hygiene hypothesis
...e most commonly accepted explanation for this high incidence of allergy and perhaps autoimmune disease is the hygiene hypothesis," Parker said. But this hypothesis has not been thoroughly tested in animal studies, he said, and the few studies conducted have focused on specific pathogens or parasites. The Duke...Failure of 'scout cells' may lead to cancer in transplant patients
...this type of cancer in transplant patients. The incidence of this cancer varies according to the organ transplanted, occurring in 1 to 2 percent of kidney transplant patients and in up to 20 percent of bone marrow and lung transplant patients. The disease usually arises within six months to a year after tra...Links between DNA damage and breast cancer studied
... a bracket that corresponds to a known rise in the incidence of breast cancer. In a second paper, the team stud... is roughly commensurate with the age at which the incidence of female breast cancer rises. "Collectively," they observe, "the findings reveal that the structura...Report focuses on the role good microbes play in future medicine
...n in newborns and children with AIDS, reducing the incidence of kidney stones, and reducing the recurrence of bladder tumors. ...Variations in detoxifying genes linked to Lou Gehrig's disease
... DNA samples from Gulf War veterans with increased incidence of sporadic ALS and has applied for their DNA from the Veterans Administration collection. ...Higher levels of obesity associated with greater health risks
...sk for all-cause mortality, CHD mortality, and CHD incidence did not differ by race/ethnicity." "There was a positive trend in all-cause mortality risk and CHD incidence with increasing weight category. This trend had borderline significance for CHD mortality among blac...A new view on Lyme disease: Rodents hold the key to annual risk
In the United States, Lyme disease incidence has skyrocketed from 497 cases reported in 1982 (the first year national statistics were collected) to a record 23,763 in 2002. Lyme disease, like other zoonoses, is transmitted by a vector that picks up the pathogen during a blood meal from a ve...Green tea and the 'Asian Paradox'
There is a lower incidence of cardiovascular disease and cancer in Asia where... the 'Asian paradox,' which refers to the very low incidence of both heart disease and cancer in Asia, even though consumption of cigarettes is greater than in m...'Smart' genetic therapy helps the body to heal itself
...and the leading cause of death in infants, with an incidence of about 1 in every 6,000 newborns. Due to degeneration of the motor neurons in the spinal cord patients develop muscle weakness and atrophy of the legs, arms and trunk. In patients with SMA the survival motor neuron genes (SMN1) is deleted, but t...New strategy developed to combat West Nile Virus
...t necessarily mean that we'll experience a greater incidence of West Nile Virus. The mosquitoes themselves must...o contact with humans ?elevating the risk of human incidence of the diseases. "Drought-induced amplification may be somewhat unique to southern Florida, where d...Control measures fail to stop spread of new H5N1 virus
... during 2004-05. This indicates an increase in the incidence of H5N1 infection in 2005-2006 compared with previous years, which suggests that H5N1 viruses have not been effectively contained. The investigators also conducted genetic studies of 390 H5N1 viruses isolated from poultry in the current study (3...Recycled paper and compost could both be key tools to control plant disease
...ntly shown that the use of composts can reduce the incidence of some important plant diseases by as much as 72%. That research, funded by the UK government's Waste and Resource Action Programme (WRAP), found that the replacement of around 20% of the volume of soil or peat by compost gave major disease control ...Incidence of stroke decreases over last 50 years
The incidence of stroke in the U.S. over the past 50 years has d...rticle. Prior estimates of long-term trends in the incidence and severity of stroke have varied. Determining trends could help guide health programs, public poli......e to age-related macular degeneration but warn the incidence is likely to rise as the population ages. In collaboration with Tinsley Ophthalmic Instruments, Dr Murray's lab has developed a lightweight instrument that can measure the levels of lutein and zeaxanthin and provide an indication as to whether low ...