PNAS study reveals why organs fail following massive trauma
...esearch priority because the survival rate has not improved in 10 years. Excitement is growing, however, because new evidence suggests that major diseases involving the immune system share some of the same mechanisms and may be cured by manipulating the same molecules. A protein called programmed cell death 1...Effective HIV control may depend on viral protein targeted by immune cells
... people receiving no antiretroviral treatment, the improved HIV control associated with Gag-specific CD8 response would probably translate into asymptomatic infection for more than a decade, compared with progression to AIDS within two to three years of infection in those with no Gag responses. The reason wh...Innovative movies show real-time immune-cell activity within tumors
...board defenses against cancer may open the way for improved immunotherapies to treat the disease. With a series of movies made under different experimental conditions, the researchers resolved important questions about the mechanisms by which T cells act against cancer. Their findings, published online Nove...Cardiologist's 'living chip' changes science of disease monitoring
...tect physiologic and chemical changes with faster, improved accuracy. These more accurate results, retrieved without invasive testing, allow for better and timely response and, the hope is, a healthier patient. How it worksUltimately, cells specific to the patient can be engineered to live on and function a...Highly concentrated botulinum preparation for cosmetic injections can result in severe illness
...2 hours of presentation) have been associated with improved clinical outcome. Suspected cases of botulism should be reported immediately to local health authorities to facilitate rapid epidemiological investigation, provision of antitoxin when indicated, and prevention of further cases," the researchers write...Walking not enough for significant exercise benefits
...ure, we found that the traditional fitness program improved aerobic fitness and reduced systolic blood pressure, more than the 10,000-step lifestyle program," Dr. Harber said. Of the 128 sedentary men and women who completed the six-month research program, those who took part in a more active traditional fitn...High levels of blindness in southern Sudan following years of war
...ealed by the researchers is particularly tragic as improved living conditions, better hygiene, and early treatment of the infection with antibiotics can prevent trachoma. Surgery for trichiasis is also very effective. The World Health Organization recommends a strategy for trachoma control known as ‘SAFE? sur...NASA study: Alaskan fires affected Houston air quality in 2004
...ses and aerosols over long distances is needed for improved understanding and air-quality forecasting. "This event highlights the critical role imported sources can have on local air quality," Morris said. ...Insulin receptor stops progression of Alzheimer's disease
...ng for cognitive impairment, and that was the most improved with the PPAR delta agonist." Researchers were not able to stop the deterioration of insulin and its receptors. However, by administering PPAR, they were able to bypass the defects in insulin signaling and preserve the cells that need insulin to thr...Computer-based 'games' enhance mental function in patients with Alzheimer's
...ent, the group that received both IPP and IMIS had improved outcome scores on both tests as compared to control; these improvements were maintained at 24 weeks. The group that received only IPP, showed improvement over the control group at 12 weeks, but the effects diminished by 24 weeks. "While Alzheimer'...New biologic treatment for tennis elbow may replace surgery for chronic sufferers
...ed the most severe tendonitis patients who had not improved with time or nonsurgical treatment. Fifteen pati...RP-treated patients' visual analog pain scores had improved 81 percent over their baseline scores. At a 2-year evaluation, 93 percent of these patients reporte...Study suggests evolutionary link between diet, brain size in orangutans
...gutans in other parts of Borneo or Sumatra. This improved feeding efficiency, coupled with a relatively small brain, would enable such animals to adapt to their conditions by both maximizing their resources and conserving energy, she said. In addition, studies by van Schaik and other scientists have sugge...Incidence of stroke decreases over last 50 years
... women. These sobering trends emphasize that while improved control of risk factors has lowered incidence of stroke, there is a need for greater primary prevention efforts to reduce the lifetime risk, severity, and 30-day mortality following stroke," the authors conclude. ...Found -- the apple gene for red
...er tests to speed up apple breeding and select for improved fruit colour. Dr Walker believes that this research could open the way to breeding new apple varieties. "With a better understanding of how apple colour is controlled we can begin to breed apples with new and interesting colour variations," she say...Report highlights change in Canada's forests
...ng costs, securing markets and focusing on new and improved products." Forests make up a significant part of Canada's economy, contributing $37.6 billion to the gross domestic product and providing more than 339,000 direct jobs in 2005. The report contains the most comprehensive and up-to-date information on...UCSD study reveals how plants respond to elevated carbon dioxide
...rlying mechanisms may make it possible to engineer improved water use efficiency in some crop plants or trees that will be exposed to higher carbon dioxide levels in the future." In the paper, the researchers also report the discovery of the first known plant with a genetic mutation that makes it strongly i...Immune cell communication key to hunting viruses, Jefferson immunologists show
...s to manipulate it and could have implications for improved vaccine development. To better understand how proteins are recognized by killer T-cells, Dr. Sykulev and his co-workers created a biosensor out of semiconductor nanoparticles called quantum dots. These served as a unique scaffold to carry presenting ......ion) for 6-9 days prior to transplantation greatly improved their subsequent engraftment in monkeys whose hematopoietic system had been destroyed through radiation. These results suggest that HOXB4-mediated expansion of stem cells could accelerate the engraftment of HSCs from sources that contain limited numb...Americans support free access to research
...vaccine trials. "Time and again the lesson is that improved knowledge in the community furthers the public health agenda." In another strong signal of broad support for public access, Sen. John Cornyn (R-TX) and Sen. Joseph Lieberman (D-CT) recently introduced the Federal Research Public Access Act of 2006 (...Scientists use gene signatures to match cancer and other diseases with potentially effective drugs
... diseases to accelerate the development of new and improved therapies for a wide range of disorders. Like the data in the current papers, the information garnered in the course of such a project would be freely available to scientists everywhere. ...