Opposing fat metabolism pathways triggered by a single gene
Regulating metabolism of fat is an important challenge for any animal, from nematodes to humans. Central players in the regulatory network are the nuclear hormone receptors (NHRs), which are transcription factors that turn on or off a set of target genes when bound by specific lipid molecules. ...Special Imaging Study Shows Failing Hearts Are 'Energy Starved'
...rect measurements of the concentrations of various important biochemicals and their chemical reaction rates within the cells of various tissues. They first performed MRS on 14 healthy volunteers to measure cardiac CK flux at rest and with pharmaceutically induced stress to determine whether increased energy de...International HapMap consortium expands mapping effort
... the HapMap Project has allowed scientists to make important analyses of the human genome that were not possibl...tanding the one-tenth of one percent difference is important because it helps explain why one person may be more susceptible to a certain disease than another. F...Vascular structure and function improve with diet and exercise
...tatoes, beans, nuts and seeds with olive oil as an important fat source, and low to moderate amounts of dairy, fish and poultry. "There have been studies looking at diet and exercise to prevent or treat cardiovascular disease," said primary investigator Robert J. Petrella, M.D., Ph.D., associate professor in ...Children's taste sensitivity and food choices influenced by taste gene
...ear to change with age. "The sense of taste is an important determinant of what children eat. We know that you...ble consumption and potentially limiting intake of important nutrients," comments lead author Julie Mennella, PhD, a developmental psychobiologist. "The recent N...Antibiotic might fight HIV-induced neurological problems
... observation holds up, minocycline could be really important for treating HIV infection in developing countries where access to traditional antiretroviral drugs is very limited," says Zink. "Most of the 40 million people with HIV infection live in these countries." ...Researchers develop rapid diagnostic tool for pathogen identification
... disease. This new technology platform addresses important challenges for infectious disease identification—sensitivity and breadth. Mass Tag PCR provides the ability to be precise in identification, as well as the ability to apply current diagnostics to more than one pathogen at a time, thereby reducing the...Effective Cancer Treatments Follow The Clock
...anism of internal clock function lets us make some important predictions of how these mice may respond to drug ...apy to make it less toxic. “There is one more very important clinical application of these findings,?Antoch said, “as they provide a rationale for developing dru...Use of Insecticides Linked to Lasting Neurological Problems for Farmers
...ental Protection Agency. "This research is really important because it evaluated the health effects of agricultural chemicals as they were commonly used by farmers. It's different from previous studies that focused on pesticide poisoning or high dose exposures, for example when large amounts of a chemical wer...LUCA technologies confirms real-time methane generation
...qing Field in Northeast China -- could prove to be important sites for the bioconversion of residual oil to methane and the restoration of these 'spent' sites to economic energy production." Potential for Methane "Farming" It has long been known that certain microorganisms are "methanogens" ?microbes that ge...Multiple Campylobacter Genomes Sequenced
...es responsible for synthesis of molecules that are important for the interaction of Campylobacter with the envi...omic analysis provides the core blueprint for this important family of human pathogens. And in doing so, it lays the foundation for the development of new ways t...A new study examines how shared pathogens affect host populations
...lker H. W. Rudolf and Janis Antonovics provides an important conceptual counterexample to the idea that sharing...cause of the epidemic. Their results have not only important consequences for understanding the role of pathogens in species interactions but also provide a pote...Potential treatments for neurofibromatosis
...varian cancers, because inflammatory cells play an important role in tumor formation in these malignancies." Neurofibromatosis results from mutations in a gene called NF 1. In humans, NF 1 mutations resulting in neurofibromatosis occur in one in 4,000 births, equally affecting both sexes and all races and eth...How the environment could be damaging men's reproductive health
...nto the sea. Additionally, the atmosphere plays an important role in their transport over long distances. POPs have a strong tendency to bioaccumulate in marine and terrestrial food webs. Humans, being at the top of the food web, particularly are exposed to POPs." The researchers found that larger amounts of ...Cricket's finicky mating behavior boosts biodiversity
... rate over another? Whatever the reason, it's very important that she exercise this preference in order to keep the species distinct." Mendelson spent three and one-half years studying the Laupala cricket with Kerry Shaw, an evolutionary biologist at the University of Maryland. The thumbnail-sized Laupala sp...Variation in women's X chromosomes may explain differences among individuals, between sexes
...nnsylvania State University. The results may have important implications for understanding the differences in traits among women and between males and females, in terms of both health and disease, said Huntington Willard, Ph.D., director of the IGSP and the study's senior author. The findings also offer new i...World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics
...Protocol treatment for diabetes, has taken another important step in the fight against diabetes. On January 19, at Kyoto University Hospital, Dr. Koichi Tanaka and Dr. James Shapiro, along with a team of Japanese surgeons, removed part of a 56-year-old woman's pancreas. Dr. Shinichi Masumoto then isolated the...Drug-resistant bacteria on poultry products differ by brand
...mental Health Perspectives. "Our use of medically important classes of antibiotics in food-animal production c... humans, but fluoroquinolones are some of the most important drugs used to treat a variety of infections, including those caused by Campylobacter. The widespread...Programmable cells: Engineer turns bacteria into living computers
...epartment of Electrical Engineering, represents an important proof-of-principle in an emerging field known as "...k from scratch, we should be able to model all the important details," he said. At some point in the future, he said, scientists will be able to choose a behavio...