Alcohol's effects on gene expression in the central nervous system
...ndividual genes and gene networks that may play an important role in determining the behavioral responses to alcohol as well as possibly influencing drinking behavior. "Thus far, genes that appear to be responsive to alcohol include genes involved in the intracellular signaling process (which can alter how th...New SARS Protein Linked To Important Cell Doorway
...ished insights into a new protein that could be an important contributor to the SARS virus' ability to cause di...he first human infections, to look for potentially important viral proteins. As reported recently in the journal Structure, their efforts revealed orf7a, a SARS...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...ycome from one with his strengths, but the work is important because itaddresses a problem arising directly from the biology."Dr. Daniel Gillespie, a pioneer in stochastic methods for modelingchemical kinetics stated, "Dr. Lok has succeeded in adapting andcreatively extending earlier developed techniques for s...Jumping gene helps explain immune system's abilities
...ll-studied cousins, theHermes protein still has an important family trait, the researchersreport. Colleagues at the National Institutes of Health found that afew key building blocks in the protein's DNA-snipping crevice areidentical to those in other jumping genes' proteins, even though theoverall sequence is ...UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections
...ll-studied cousins, theHermes protein still has an important family trait, the researchersreport. Colleagues at the National Institutes of Health found that afew key building blocks in the protein's DNA-snipping crevice areidentical to those in other jumping genes' proteins, even though theoverall sequence is ...New therapy for HIV/AIDS eliminates needles and excessive toxicity
...ll-studied cousins, theHermes protein still has an important family trait, the researchersreport. Colleagues at the National Institutes of Health found that afew key building blocks in the protein's DNA-snipping crevice areidentical to those in other jumping genes' proteins, even though theoverall sequence is ...Gene sequencing explains bioremediation 'bug'
...ll-studied cousins, theHermes protein still has an important family trait, the researchersreport. Colleagues at the National Institutes of Health found that afew key building blocks in the protein's DNA-snipping crevice areidentical to those in other jumping genes' proteins, even though theoverall sequence is ...New studies suggest airborne SARS transmission is possible
...irus has been controversial," said Dr. Tong, "this important work shows beyond doubt that SARS coronavirus aerosol generation can occur from a patient with SARS." The Hong Kong study provides additional, complementary evidence that the virus may be capable of spreading through the air. ...New Breast Cancer Test Could Save Lives
...etect cancer at an early stage ?which is extremely important for successful treatment - many women are dependent on self-examination which can prove unreliable. This latest technology has the ability to image through dense breast tissue, and therefore can reach a far wider section of women than X-ray mammograp...The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures
... own right and provide the basis for modeling many important proteins.?/p> Some of the newly determined str... “There are a lot of proteins that are incredibly important to understanding human biology and medicine, yet we know very little about most of them,?said Norvel...The BIOS Initiative - open source biotechnology is born
...red it partially this week , this initiative is so important that it deserve another, more complete description. In a publication today in the prestigious scientific journal, Nature, a team at CAMBIA in Canberra unveils the 'kernel' of the world's first 'explicit open source' biotechnology toolkit. These too...Estrogen-like Component of Plastic Stimulates Growth of Certain Prostate Cancer Cells
...e cancer cells from studies on animals. It is also important tonote that our study demonstrates that the actual dose of BPA exposuremay change the biological response,?Dr. Knudsen said.The safety of BPA has been under intense debate for several years, withsome arguing that exposure to the chemical among humans...Beyond lithium for bipolar disorder
... Lithium is known to inhibit the production of an important cellular switch, called inositol monophosphate, so the researchers set out to find genes that were activated by this inhibition. They treated slices of rat brain with lithium chloride as well as a chemical that depletes inositol. The also treated oth...Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease
...nomers become irreversible. Defining that point is important because "the fibrils are virtually indestructible once formed," he said. "How all these monomers interact to form these amyloid fibrils is just not known at this point," said Akhremitchev. "And that is why it is such a great challenge. That's what w...Newly Discovered Compound Blocks Known Cancer-Causing Protein
...or of Icmt, a protein that has been shown to be an important player in keeping a cancer-causing gene called 'Ras' turned on inside cells," said Casey. Ras is a normal genetic component of the cell, but mutations in the gene can cause it to become stuck in an "on" position, promoting uncontrolled cell growth. ...Tiny scaffolding allows stem cells to become working fat cells
... surgery and other clinical needs, and may even be important for curing type II diabetes. Douglas Kniss, profe...a test bed for this approach to cell growth offers important medical potential. While experts once thought a persons number of fat cells was set at birth, they n...Plants defy Mendel's inheritance laws, may prompt textbook changes
...e therapy, Pruitt said the discovery has opened an important new line of thinking. The other researchers involved with this study were Jennifer Victor, a former Purdue graduate student now at Butler University; and Jessica Young, a botany and plant pathology laboratory technician. Lolle, a Purdue research sci...UCSD discovery may help extend life of natural pesticide
...nsect biologists that certain proteins function as important Bt toxin receptors in some cases, how might glycolipid and protein receptors cooperate to engage this intoxication program? If the field can figure this out, it might allow for the engineering of toxins that can utilize either type of receptor altern...Scientists identify new model Of NK cell development
...n some gaps." Still, the findings appear to offer important new information about NK killer cells that may ultimately be helpful in designing more effective treatments for cancer and other diseases says Caligiuri. "NK cells are the 'minutemen' of the defense system ?the first to respond to an attack. The mor...Study of genomic DNA leads to new advances in cancer diagnostics
...cancer cell interacts with its microenvironment is important for cancer progression. Such interactions must be aberrant for abnormal cell growth and metastasis to occur. Indeed, Dr. Maniotis and his colleagues found that the extracellular matrix (ECM), or the microenvironment surrounding the cell, influenced w...