Timing is everything: First step in protein building revealed
...om the ribosome, or thatits release might serve an important purpose, so this was a completelyunexpected result," says graduate student David Maag, first author ofthe paper."It's impossible to know for sure whether eIF1 is released completelyin living creatures, but in our laboratory experiments that is clearl...Plants, animals share molecular growth mechanisms
...t controls formation of actin filaments, which are important for cell growth and movement. Actin filaments orga...ic to plants. We'd like to know if this section is important and whether it regulates DIS3 or the whole WAVE complex." For growth and development biochemical pr...Scientists detect probable genetic cause of some Parkinson's disease cases
...rogenetics."Knowing that this mutation is not only important in familial forms ofdisease, but in typical sporadic disease, where there is no strongfamily history, could lead to earlier detection of Parkinson's disease.Further study of how this gene works also might help scientistsidentify new treatments."In ad...Computers to be used to find blueprint for new influenza drug
...rint for a new way of fighting influenza is a very important task," said Professor Williams. “We often think o...n Asia. “If we are successful, we will have taken important steps in finding a new way of fighting influenza and other diseases. It will then be for the pharmac...A much-needed shot in the arm for HIV vaccine development
...e field."Ho urges the Enterprise not to ignore the important contributions madeby scientists outside of the collaboration. "It is my contention thatgreat new ideas are as likely to come from curiosity-driven basicstudies as from the mission-oriented approach that is represented bythe new proposal."The PLoS Med...New Technique for Tracking Gene Regulators
... for causing Huntington’s disease inmice, which is important for making advances in understandingHuntington’s disease in humans, and genes that may play an importantrole in certain cancers.“This technique can be applied to any protein that binds to specificsequences in the DNA and promises to be a very useful ...Bound for destruction: Ubiquitination protects against improper Notch signaling
The Notch pathway is an important molecular signaling mechanism whose existence has beenknown, or at least hinted at, for nearly a century since theidentification of a mutant strain of Drosophila fruit flies with“notched?wings in Thomas Hunt Morgan’s lab in 1910. Later studiesreveale...HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs
...of protease inhibitors because these drugs are too important for the successful treatment of HIV viral infection and control of AIDS. But hopefully our findings will save lives by alerting the physician to yet another side effect associated with this class of drug." Dr. Ackerman is director of Mayo Clinic's L...Research on Worms Yields Clues on Aging
...rding toKornfeld."Our experiments show there is an important connection between neuralfunction and longevity," Kornfeld says. "We're continuing this line ofresearch to identify the precise functions of the nervous system thatcause the worms to live longer."Because the researchers found that anticonvulsants aff...Imaging Lymph Nodes with Nanoparticles
... : Accurate staging of cancers is one of the most important parts of thework up of patients for both prediction of prognosis and determinationof the most appropriate treatment. And an essential part of this workup is assessing whether or not there has been lymphatic spread. Currentmethods include surgical rem...“Nano-scissors?laser shows precise surgical capability
...e key to understanding nerve regeneration andis an important step toward treatment of human neurological diseas...lionth of a billionth of asecond.“The time is very important here,?she says. “Because it happens sofast, there isn’t enough time for heat to diffuse out, so we d...Genome-wide mouse study yields link to human leukemia
...nome-wide basis in a mouse, and the findings offer important implications for patient care, since we know that methylation, which alters gene function, can be reversed," says Christoph Plass, senior co-author and a member of the OSUCCC's Molecular Biology and Cancer Genetics and Experimental Therapeutics Progr...Breakthrough Microarray-based Technology for the Study of Cancer
...s in the number of gene copiespresent in cells are important events in the genesis and progression ofcancer," said Michael Bittner of the Translational Genomics ResearchInstitute. "Agilent has now taken array-CGH experiments into a newrealm of resolution, sensitivity, and reproducibility that allowsreliable de...U of M researcher examines newly emerging deadly disease
...sed by the leakage of blood into the skin. "It is important to alert medical professionals about the symptoms and treatments of this new deadly disease," said Patrick Schlievert, Ph.D., professor of microbiology at the University of Minnesota Medical School. "We are continuing to study and monitor cases of pu...Study finds more than one-third of human genome regulated by RNA
...rs determined which portion ofthe microRNA is most important for this process, and identifiedadditional determinants in the messenger RNA that are likely tocontribute to recognition by microRNAs.These findings contribute to the recent interest in potentialtherapeutic uses of RNA. For example, using a technique...Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa
...etinal diseases, we were able to be a part of this important study." Pre- and post-surgery patients are evaluated by a team of researchers working at the Eye Center and the VA Rehabilitation R&D Center including Ronald A. Schuchard, PhD and Claire Barnes, PhD. "This clinical trial will help evaluate the ...... “Knowing the history of populations is critically important to managing their future,?says Palumbi, “especially for populations like these whales that have figured out how to dodge the effects of climate change.?/p> Undertakers in the Deep Sea—A New World Discovered Earlier forensic DNA work by Palumbi a...NYU researchers simulate molecular biological clock
...rs determined which portion ofthe microRNA is most important for this process, and identifiedadditional determinants in the messenger RNA that are likely tocontribute to recognition by microRNAs.These findings contribute to the recent interest in potentialtherapeutic uses of RNA. For example, using a technique...Mitochondrial DNA mutations play significant role in prostate cancer
Mutations in mitochondrial DNA (mtDNA) playan important role in the development of prostate cancer, accord...ncing evidence that mitochondrialmutations play an important role in prostate cancer," said Dr. Petros."This is the first evidence that individuals who inherit a......ium bank." If calcium, which is necessary for such important functions as maintaining the brain and heart, runs...d LAGT has just been recognized as one of the most important discoveries of the year by the Orthopedic Research Society (ORS) and the American Academy of Orthope...