Researchers make gains in understanding antibiotic resistance
...ecise structural basis of resistance and even more important to do something about it." Steitz cited, for examp...so analyzed the structure of five other clinically important antibiotics ?azithromycin, telithromycin, clindamycin, and virginiamycin M and virginiamycin S ?boun...Harmful chemicals may reprogram gene response to estrogen
...he National Academy of Sciences. The discovery is important because it changes conventional thinking about the...ng critical developmental stages, may be much more important in determining who develops cancer as an adult." The researchers used a special strain of rats with...Disease diagnosis, biodefense among UH chemical research projects
...rces of carbohydrate-protein interactions that are important in biological systems. # Roman S. Czernuszewicz, ... rapid microbial identification." This research is important because infectious diseases cause 26 percent of global mortality and are the third leading cause of ...Silence the gene, save the cell: RNA interference as promising therapy for ALS
... Huntington's disease," notes Aebischer. "But it's important to note that the safety of delivering lentiviral vectors to the nervous system will have to be carefully examined prior to treating patients."...Brain-mapping technique aids understanding of sleep, wakefulness
... are connected to other neurons in the brain is an important step toward understanding how and why we sleep. M...sa. It's a seesaw, or flip-flop, mechanism. That's important because you don't want to be half-asleep. You want to be either completely awake or completely aslee...Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis
... numbers of blood cells. This process is extremely important during the initial development of the blood system...llowing loss of Mcl-1, demonstrating that Mcl-1 is important only in certain cell types. Finally, the investigators showed that growth factors (natural proteins ...Revolutionary nanotechnology illuminates brain cells at work
...een impossible to accurately measure the levels of important chemicals in living brain cells in real time and at the level of a single cell. Scientists at the Carnegie Institution's Department of Plant Biology and Stanford University are the first to overcome this obstacle by successfully applying genetic nano......g Administration (FDA) today announced a series of important changes pertaining to the marketing of the non-steroidal anti-inflammatory class of drugs, including COX-2 selective and prescription and non-prescription (over-the-counter (OTC)) non-selective NSAID medications. A list of these products is available...New Estimates For The Causes Of Child Deaths Worldwide
...volved in making the world's children count. It is important to look at the single most important determinant of childhood death -- which has to be poverty. Childhood mortality is strongly inversely...Yeast Network Prevents Damage By Oxygen Radicals
... "DNA repair and cell cycle control mechanisms are important guardians against cancerous changes in human cells," says Dr. Richard Kolodner, LICR Member and senior author of the study. "However, the effects of ROS on these cellular responses have not been well characterized. We've now identified a group of gen...Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes
...te clinical implications, the study may offer more important clues for further research. It may be that dolichoectasia causes or contributes to small vessel disease, and/or that the two have common causes. Nearly a quarter of all strokes arise from blood flow problems in the smallest blood vessels of the brai...Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment
...re the only eggs she's ever going to have, so it's important that as many as possible remain viable," says Gary D. Smith, Ph.D., associate professor of obstetrics and gynecology, urology, and molecular and integrative physiology at the U-M Medical School, and director of the Fertility Counseling and Gamete Cry...Canada approves marijuana-based pain spray
...ffective pain control and management are extremely important in a disease like MS,?said Dr. Allan Gordon, Neuro...trol of their pain,?said Dr. Gordon. “This is very important since pain severity varies between different patients and even in the same patient at different time...UNC launches study of liver injury caused by drugs
...ng problem," Watkins said. DILIN also may provide important insight into medical problems beyond liver injury induced by drugs, he added. "Drug-induced liver injury is an ideal model to study how genes and environment interact to produce disease in some but not all people. We hope the factors identified by D...Study reveals new technique for fingerprinting environmental samples
...wed researchers to forge ahead with studying genes important in disease processes, long before the completion o...at it offers an easily accessible window into that important part of the biosphere with significant impact on the environment. DOE JGI postdoctoral fellow Susan...Used in a new way, RNA interference permanently silences key breast cancer gene
...STAT3 is controlling TWIST expression, and this is important to know with regards to activated STAT3 and its involvement in cancer metastasis," Arlinghaus says. When the mouse breast cells transduced with STAT3, shRNA were then tested in immunocompetent mice, researchers found that the treated breast cancer c...Different microarray systems more alike than previously thought
... want to look at changes in gene expression. It is important for both cost and quality of data," she said. "But people are in need of clear information in making the choice." For the study, five expert labs used Affymetrix GeneChips, three used "homemade" versions called two-color spotted cDNA arrays, and two...Brain Scans Reveal How Gene May Boost Schizophrenia Risk
...ort this tuning model," said Berman. "The study is important for our understanding of schizophrenia because it clarifies the neural mechanism for a well-established risk gene." Also participating in the NIMH brain imaging study were: Dr. Daniel Weinberger, Philip Kohn, Dr. Bhaskar Kolachana, Shane Kippenhan, ...New understanding of DNA repair may pave way to cancer treatments
... known for its role in gene regulation has another important function, that of initiating DNA repair. The study... studies evolved from the finding that ATF2 has an important role in the development and progression of melanoma tumors. Inhibition of ATF2 was found to sensitiz...Cerebral navigation: How do nerve fibers know what direction to grow in?
...researchers from Children's Hospital Boston reveal important insights into how inhibitory cues affect the growth cone, and identify possible targets within axons that could be blocked to overcome this inhibition. Such intervention could possibly enable damaged axons to regenerate (normally impossible in a matu...