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Tag: "impaired" at biology news

Penn researchers link cell's protein recycling systems

...en we knew that this system can compensate for the impaired proteasome function, which in itself tells us that...earchers suggest further that when proteasomes are impaired or overwhelmed, which leads to accumulation of defective proteins, HDAC6 facilitates delivery to the...

Research finds that circadian rhythms dominate all life functions

...loping ways to treat people who overeat because of impaired leptin signaling. Circadian rhythms are biological rhythms that cycle over a period of about 24 hours and regulate timing for most physiological functions and behaviors such as sleeping, eating and activity. As a checks-and-balances procedure, Ptit...

Mice with a migraine show signs of brain damage

...patients having a migraine attack are functionally impaired from the pain. It’s also been shown recently that with repeated migraines, a person’s cognitive abilities decrease. But actually doing damage to the brain ?that is a surprise.? Deborah Friedman, M.D., a neurologist who was not involved in the study...

A cherry on top: Tart cherries may alter heart/diabetes factors

...t-linked high blood pressure, high cholesterol and impaired glucose tolerance. For 90 days beginning in their sixth week of life, the rats were fed either a carbohydrate-enriched diet or a diet that, by weight, included 1 percent cherries or 10 percent cherries. The higher cherry dose was used to look for...

Amphibians in losing race with environmental change

... of the Earth's ozone layer, is causing mutations, impaired immune systems and slower growth rates. Through evolution, amphibians were able to adapt to changing UV-B levels in the past, but the current change has occurred too rapidly. In the past, water was reasonably pure and clean. But increased "eutro...

Chronic fatigue syndrome impairs a person's slow wave activity during sleep

...t reduced electroencephalograph (EEG) activity and impaired sleep regulation. A study published in the May 1st issue of the journal SLEEP finds that CFS is also associated with a blunted slow wave activity (SWA) response to sleep challenge, suggesting an impairment of the basic sleep drive and homeostatic re...

Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness

...health and disease. "When nitric oxide function is impaired by disease, therapeutic agents like beta-agonists in asthma and adrenergic stimulants in heart failure will work less well. The key now is to determine how best to manipulate these ubiquitous receptors, together with nitric oxide for the treatment of...

First clinical trial of gene therapy for childhood blindness

...s at the back of the eye. This results in severely impaired vision from a very young age and there are currently no effective treatments available. The new technique that will be used in the trial involves inserting healthy copies of the gene into the cells of the retina to help them to function normally....

Simple home spit test to spot deadly pre-eclampsia

...increased levels of which are thought to be due to impaired kidney excretion in pre-eclampsia. 'A salivary urate test is simple, non-invasive, quick and cheap and can be done at any time. As a metabolic test independent of blood pressure, it may obviate the need for hospital admission,' said retired hospit...

Gene found for rare disorder may reveal new pathway in mental retardation

...orms, but classically includes mental retardation, impaired growth, heart defects, feeding problems, deformed upper limbs and distinctive facial features. In the current study, mutations in two genes of interest cause mental retardation, but with less pronounced facial features and none of the limb defects...

Tracking sperm whales and jumbo squid

...ual acuity and swimming speed may be significantly impaired because of an inadequate supply of oxygen—a condition known as hypoxia. "Squid need a constant supply of oxygen to support their metabolism," Davis added. "Sperm whales, on the other hand, take the oxygen down with them bound to the hemoglobin in ...

When your brain talks, your muscles don't always listen

...tanding of motor-control mechanisms in general and impaired control in patient populations." Shedding light on the communication between neurons and muscles, and how it changes as we age, may lie right at our fingertips, according to Knight's research. Using an experimental apparatus he and his students...

Common gene version optimizes thinking -- but with a possible downside

...r schizophrenia, a severe mental illness marked by impaired thinking, scientists at the National Institutes of...al illness marked by delusions, hallucinations and impaired emotion that affects one percent of the population. "We have found that DARPP-32 shapes and cont...

Robotic exoskeleton replaces muscle work

...e next step is to test the device on patients with impaired muscle function, Ferris said. ...

Robotic therapy helps restore hand use after stroke

...California, Irvine study. Stroke patients with impaired hand use reported improved ability to grasp and release objects after therapy sessions using the Hand-Wrist Assisting Robotic Device (HOWARD). Each patient had at least moderate residual weakness and reduced function of the right hand, although the a...

Molecular differences between early and advanced melanomas could provide new drug targets

...h greater Akt expression, there was an increase in impaired mitochondria-- the energy factories of cells. Their research showed, however, that these mutations in mitochondria were likely the result of the prolonged exposure to increased oxidative stress caused by Akt overexpression, but that the mitochondrial...

Angelman syndrome deficits rescued in mice

... poorly on learning and memory tasks and displayed impaired motor coordination. The double mutants, however, showed normal learning and memory and motor coordination. And while the Angelman mice were also prone to seizures, the double mutants showed very low seizure susceptibility. Weeber was surprised ...

Shedding new light on proteorhodopsin

...robe's ability to respire is suddenly impaired. We impaired respiration through either oxygen depletion or the respiratory poison azide." The Berkeley researchers monitored single cells of E. coli and observed the response to light of the proton motive force (pmf), the electrochemical potential of protons ...

MU researcher placing eye implants in cats to help humans see

...strom has performed surgeries in severely visually impaired or blind cats. During the surgery, Narfstrom makes two small cuts into the sclera, the outer wall of the eyeball. After removing the vitreous, which is the gelatinous fluid inside the back part of the eyeball, Narfstrom creates a small bl...

Researchers discover gene crucial for nerve cell insulation

...athies can result in numbness, weakness, pain, and impaired movement. They include one of the most common genetically inherited disorders, Charcot-Marie-Tooth disease, which causes progressive muscle weakening. The myelin sheath that surrounds a nerve cell is analogous to the insulating material that coat...

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