Brown team finds crucial protein role in deadly prion spread
... "The protein fragmentation we studied has a big impact on how fast prion diseases spread and may also play a role in the accumulation of toxic proteins in neurodegenerative diseases like Parkinson's," said Tricia Serio, an assistant professor in Brown's Department of Molecular Biology, Cell Biology and B...Satellites shed light on global warming
...re to get a better idea of the likely scale of the impact of climate change. In addition, the melting of sea...y half a degree Celsius a decade and are having an impact on the ice shelves and glaciers. Innsbruck University's Professor Helmut Rott has been observing the...Protein therapy may reduce infarct size in heart attack patients
...ed as an exploratory study to assess the potential impact of KAI-9803 in this “first-in-human?study. Results indicate that KAI-9803 may be associated with less myocardial necrosis with lower CK-MB AUC values at all dose levels. Furthermore, improved tissue perfusion (measured during coronary angiography ...Bacterial response to oxidation studied as toxin barometer
...l deliver the paper, “Predicting the public health impact of oxidative toxins using a bacterial glutathione-gated potassium efflux stress response biosensor?(GEOC 51) at 3:25 p.m., Monday, March 26, in McCormick Place North room N427A. Rzigalinski and Nancy Love are the co-authors. ...'Hidden-hero' microbes in soil, water may help naturally clean toxic sites
...ventional methods. "The stakes are high and the impact potentially huge," Kostka said. Together, those 7,000 U.S. sites encompass an estimated 1.7 trillion gallons of contaminated water -- that's about four times the nation's daily water consumption -- and about 40 million cubic meters of contaminated so...Dinosaur extinction didn't cause the rise of present-day mammals, claim researchers
...sted 85 million years ago, and survived the meteor impact that is thought to have killed the dinosaurs. However, throughout the Cretaceous epoch, when dinosaurs walked the earth, these mammal species were relatively few in number, and were prevented from diversifying and evolving in ecosystems dominated by ...NIH neuroscience microarray consortium launches high-throughput genotyping services
...enotyping services will ultimately make a dramatic impact in clinical care of neurological disorders." About 10,000 investigators funded through the 15 different NIH institutes are part of the NIH Neuroscience Blueprint and have access to the technology and expertise within the national Consortium. "No...100 percent juices found as beneficial to health as fruits and vegetables
...s. As a result, they determined that the positive impact fruits and vegetables offer come not from just the fiber but also from antioxidants which are present in both juice and the whole fruit and vegetables. This 2006 review of the literature states, “When considering cancer and coronary heart disease...Major link in brain-obesity puzzle found
...the use of energy from food. It even moderated the impact of a high-fat diet on body weight. The experiments were performed in mice, including two types of mice that the team altered genetically so that they only expressed a unique form of the SH2B1 protein in their brain cells. The protein occurs elsew...Overfishing large sharks impacts entire marine ecosystem, shrinks shellfish supply
...ousie. "This ecological event is having a large impact on local communities that depend so much on healthy fisheries," says Charles Peterson, a professor of marine sciences biology and ecology at the Institute of Marine Sciences, University of North Carolina at Chapel Hill and co-leader of the study. ...Widely used hepatitis B drug spurs HIV drug resistance
...increasing concentrations, the drug had no greater impact on suppressing HIV replication. HIV is a virus renowned for its ability to change form and thus evade or develop resistance to therapies designed to stop its action. Similar testing with entecavir, immune cells and the M184V form of HIV showed ...Common cold virus may kill breast cancer cells
...l chemotherapy and radiation treatment, which also impact on normal body cells. "In theory, the virus is ab...east cancer research in order to have the greatest impact on the disease. The NBCF has thrown its weight behind a National Action Plan for Breast Cancer Res...Chronic pain up almost 40 percent among US workers in past decade
...ing to a growing trend of presenteeism ?a negative impact on work despite being physically present at the jo...in must become their own advocates, understand the impact of their chronic pain and work with their healthcare provider to identify appropriate treatment opti...How does your brain tell time?
...ed, "the ripples of water produced by the pebble’s impact act like a signature of the pebble’s entry time. The farther the ripples travel the more time has passed. "We propose that a similar process takes place in the brain that allows it to track time," he added. "Every time the brain processes a sen...St. Jude announces breakthrough in eye cancer treatment
...cancers. This work is likely to have its biggest impact on the care of children with retinoblastoma internationally, according to Dyer. Most children in the United States with retinoblastoma do not die from the disease because they benefit from early detection and advanced medical treatment. The complex t...ASU researchers test antibacterial effects of healing clays
...emical reactions from these sites have an enormous impact on the geochemistry of the local environment. Williams is passionate about her subject: "Clays are as individual in character as people are in personality. They can be as old as Precambrian time (probably older, since meteorites contain clay miner...By 2048 all current fish, seafood species projected to collapse
...also delved into historical archives to assess the impact of humans on marine ecosystem overdecades and cent... losing a key source of food. Damage to the oceans impact not only fisheries, but the ocean ecosystem's overall productivity and stability. Specific services ...Early-stage immune system control of HIV may depend on inherited factors
...enetically determined, seems to have a significant impact on the specificity and strength of that response. ...sponse may be important to vaccine design, and the impact of an individual's genetic HLA Class I background implies that a successful vaccine would have to ov...Salmon farms kill wild fish, study shows
...tical modeling in one system to estimate the total impact of the farms." The primary sea lice hosts are ad...to combine this information and estimate the total impact of the farms." "The work is of an impeccably high standard, and will be very difficult to refute,"......t into how the disruption of circadian rhythms can impact well-being and physiology, and how those impacts might change with age. The mouse study is reported by a group led by Gene Block and Alec Davidson of the University of Virginia and appears in the November 7th issue of the journal Current Biology, pub...