First study to show how immune cells 'speak' to each other in vivo
...n-presenting brain cell, in laboratory rats. This immunologic synapse, or junction where signals are shuttled between two immune cells, has previously only been observed in cell cultures, in part because of the limitations of imaging and the rapid, touch-and-go nature of the communication itself. According to...Spousal illness can trigger partner death
...d lack of social support may also adversely affect immunologic measures, so spousal hospitalization may have physiological effects on partners." "This is a highly innovative study--in an enormous sample of older people--demonstrates yet another important connection between social networks and health," says Rich...The reason why antiviral therapy can't annihilate HIV infection, and what to do about it
...ome reactivated, most likely as a result of normal immunologic responses to various antigens and cytokines. In turn, virions released during the reactivation process may spread to neighboring resting as well as activated CD4+ T cells; direct cell-to-cell spread in the absence of virion release may also occur. ...Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease
...'s disease, with no evidence of adverse effects or immunologic reaction related to the study treatment. Furthermore, patients in the trial, at one year, exhibited a statistically significant improvement (27%, p = .04) in motor function on the side of their body correlating to the treated part of the brain, as m...Embryonic Stem Cells Treated With Growth Factor Reverse Hemophilia In Mice: UNC Researchers
...n. This occurred even in mice that were a complete immunologic tissue mismatch to the PEPs. In addition, the incidence of teratomas was low." The researchers believe this study demonstrates the power of multidisciplinary collaboration, said co-lead author Dr. Bruce A. Cairns, assistant professor of surgery and ...HIV vaccine trial breaks ground for future research
...which address the vaccine efficacy results and the immunologic responses of the study participants. The vaccine, produced by VaxGen, was a recombinant construct of the HIV envelope glycoprotein, similar to the type of vaccine used to develop a vaccine for hepatitis B. The vaccine was tested in a double-blind, r...Elusive HIV shape change revealed; Key clue to how virus infects cells
... forms and try to understand whether there are any immunologic properties that differ and that might provide a route to new vaccine or drug strategies," Harrison says. ...