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Tag: "immunization" at biology news

Progress toward an antitumor vaccine

... clear the way for the development of vaccines for immunization against tumor cells.”...

Genetic factors are linked to fever following smallpox vaccination

...e the crowning event of the 20th century. However, immunization with live virus particles, as in the smallpox vaccine, can sometimes cause reactions that range from fatigue to serious illness. In recent studies testing the safety and potency of stored smallpox vaccine, which uses live vaccinia virus, some in...

New vaccine prevents CMV infection and disease in mice

...a vaccine with a one-two punch that combines a DNA immunization that targets T-cells to essential genes required for CMV replication, with a killed virus that prompts the body’s B-cells to generate an antibody response. The vaccine contains the DNA of two essential genes that are essential for replication o...

New study suggests potential for a broadly-protective HIV vaccine

... HIV-1 strains. Antibodies produced as a result of immunization neutralized all 48 strains of HIV-1 tested. The results are encouraging for vaccine development, because they showed that it is possible to elicit a broad-spectrum antibody response....

Thymus transplants gives hope to babies with fatal immune disease

... other children her age face -- standard childhood immunization shots. ...

NIAID expands capability for influenza research and surveillance

...ctions, and will study the effectiveness of annual immunization programs using inactivated or weakened (live, attenuated) flu virus vaccines. The Rochester center also will perform clinical immunological studies to better define human immune responses to influenza vaccination and infection. Additionally, the cent...

Mechanisms involved with tumor relapse identified

...tem ?by introducing an antibody or lymphocytes, or immunization with a tumor vaccine ?to recognize and eradicate tumor cells. Using a transgenic mouse model of breast cancer, researchers found that interferon gamma, a cytokine or chemical messenger that is produced by cells of the immune system upon activatio...

CSHL research ties harmless viruses to cancer

...s is consistent with the successes of preventative immunization against hepatitis B and papilloma viruses, which both cause cancer. Lazebnik and his CSHL colleague Dominik Duelli estimate that at least 18 of 29 virus families that infect human cells have species that fuse cells, which implies that CIN and cancer ...

High-dose flu vaccines appear to safely boost immunity in elderly

...vents or side effects. Blood was drawn before the immunization and one month after. On average, individuals who ...who received the 15 ìg dose, most reactions to the immunization were mild. Although current vaccines are sufficient to protect younger adults from influenza, the e...

HIV vaccine takes different tack to boosting immune response

...ient at stimulating the body's immune cells. Most immunization attempts to stimulate an immune response to HIV in...ll response by inhibiting SOCS1." Chen hopes this immunization approach of inhibiting SOCS1 will help develop more effective prophylactic as well as therapeutic va...

Congenital rubella syndrome nearly eradicated in the US

...en born in the U.S. The remarkable success of the immunization program to eliminate rubella is due to joint effor...cording to the statement. Maintaining high rubella immunization rates is crucial to the continued success of these efforts. The statement concludes: "Effective stra...

Jefferson researchers building a better rabies vaccine

...al, and have developed a very safe vaccine for the immunization of wildlife," says Bernhard Dietzschold, DVM, professor of microbiology and immunology at Jefferson Medical College of Thomas Jefferson University in Philadelphia, who led the work. "As a result, we think we have engineered a virus which is nonpathog...

Mice studies illustrate potential of chimp/human antibodies to protect against smallpox

... National Academy of Sciences (PNAS). A worldwide immunization program officially eradicated naturally occurring ...f the variola virus that causes smallpox. Vaccinia immunization has been proven effective in generating immunity against smallpox virus and other orthopoxviruses, i...

H5N1 avian flu virus vaccine induces immune responses in healthy adults

...to the vaccine--so we can achieve a more practical immunization strategy." In addition, the U.S. Department of Health and Human Services is pursuing other approaches to an H5N1 vaccine, including vaccines made in cell cultures rather than grown in eggs. H5N1 avian influenza viruses are of enormous concern to pub...

DNA gene vaccine protects against harmful protein of Alzheimer's disease

...vant was needed for antibody production. The gene immunization is now undergoing further animal studies, with the ultimate goal being a clinical trial in humans. The researchers also plan to see if it can reverse the size of established plaques in the brains of mice. ...

Birth defects: 8 million annually worldwide

...vent severe congenital hypothyroidism; and rubella immunization to prevent congenital rubella syndrome. Recommendations in the report with both immediate and long-term impact include those that strengthen medical genetics services. "Building such services would allow nations to reduce the toll of death and di...

Needle-free immunizations

...ization has estimated that as many as one-third of immunization injections are unsafe in four of it six geographic...rtunately, because of the development costs of new immunization methods, use of needle-free immunization might initially push the direct cost of immunizations highe...

Serious adverse reactions to smallpox vaccine appear to be limited

...n the December 7 issue of JAMA. Routine childhood immunization against smallpox in the United States ceased in 1971, according to background information in the article. Although the World Health Organization declared in 1980 that smallpox had been eradicated worldwide, there is concern that smallpox virus may ex...

Agricultural workers at increased risk for infection with animal flu viruses

... flu pandemic surveillance plans and antiviral and immunization strategies, according to the study's co-investigator, Gregory C. Gray, M.D., director of the University of Iowa Center for Emerging Infectious Diseases. "If migratory birds introduce the H5N1 bird flu virus into swine or poultry populations in this ...

New study shows measles immunization may prevent fatal brain infection

...global efforts to reduce measles mortality through immunization programs. Despite recent reductions in the worldwide toll of measles, he noted, the disease still accounts for almost half of the 1.6 million annual childhood deaths due to vaccine-preventable diseases. ...

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