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Tag: "immune" at biology news

New Look at DNA Hints at Origin of UV Damage

...also responding to them. The ability of its innate immune system to respond appropriately to specific bacter...rulence factors but also to study conserved innate immune responses to the bacterium," Aballay said. "This may help us in developing strategies to protect hum...

Can our genes tell the story of our divergence?

...vidence for positive selection in genes related to immune defense. Immunity genes, the authors explain, were likely targeted throughout mammalian evolution, while the perception and olfactory genes probably reflect primate-specific adaptations. Nielsen et al. also found a "surprising number" of tumor-suppr...

Unexpected lock and key mechanism found for the assembly of tumor blood vessels

...nd pair previously identified as key regulators of immune cell function puts the finishing touches on newly ... alpha4beta1 showed that the protein worked in the immune system by binding with another molecule called VCAM, so the researchers next looked for evidence of ...

Researchers seek to discover what really happens when a virus enters the body

... developed the "danger model," suggesting that the immune system is more concerned with damage detected on t...from within the body. The recognition triggers the immune system's attempt to eliminate the invader. What the immune system actually does, according to Matzin...

Improving the potential of cancer vaccines

...ecial stretch of genetic material may turn off the immune suppression that stymies attempts to fight cancer ...function of a special group of T cells to suppress immune response to tumors and even infectious diseases. "Since 1995, many groups have tried to develop a v...

Bacteria use host's immune response to their competitive advantage

.... But long before these bacteria break through our immune defenses, they must first compete against other ba...on bacterium that infects children--stimulates the immune system to send out specialized white blood cells that attack its competitor, Streptococcus pneumonia...

New protein vital for immune response is found in surprise location

... newly discovered protein not only is vital to the immune system's ability to fight off viral infections but...k previous notions about the workings of the human immune system. Researchers at UT Southwestern Medical Center said their findings may lead to new therapies...

Gene expands malaria's invasion options

...ways to invade red blood cells, evading the body's immune system and complicating efforts to create effectiv...e adaptability in the face of receptor changes and immune system responses," the team concluded. The results have important implications for the design of a...

Fragment of yellow fever virus may hold key to safer vaccine

... have found the crucial bit of virus that people's immune systems need to spot and quash this often-fatal re...egion on one of the viral proteins that elicits an immune response. Antibodies produced by the immune system interact with this part of the protein, known as ...

Redesigned protein accelerates blood clotting

...er of those born with no factor VIII suffer severe immune reactions that render the treatment inactive. In a...ose, would reduce the cost and, potentially, avert immune reactions," Fay said. Study Details Blood clotting involves more than a dozen clotting factors, ma...

New type of rejection blocker protects kidneys after transplant

...clinical trial, a new drug that selectively blocks immune responses has proved as effective in preventing ac...e of a new type of treatment based on blocking the immune system's reaction to a transplanted organ without hampering the body's ability to fight diseases and...

Hepatitis C responds best to combo of ribavirin and interferon, study concludes

...ombination with interferon it appears to boost the immune system and help slow virus replication. The researchers were measuring failure to respond adequately to treatment under each course of treatment. In tests for presence of the virus among those who had never been treated for the disease, 83 percent ...

Pregnant women at higher risk for HIV, Uganda study finds

...onal changes affecting the genital tract mucosa or immune responses," said Gray. ...

Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress

...es such as the changes of autonomic, endocrine and immune function." Furthermore, Soya added, "cannabinoids are relevant to potential relief in such disease situations in the brain as multiple sclerosis and epilepsy, or feeding disorders. In these, their effects are similar to marijuana, except for the pos...

Gene therapy advance treats hemophilia in mouse models

...ffects. For example, if the gene were expressed in immune cells instead of liver cells, it could lead to a damaging immune response." McCray said the team now is studying additional ways to make the hybrid vector express t...

'Jumping genes' contribute to the uniqueness of individual brains

... to create diversity in brain like there is in the immune system, and the immune system's diversity is perhaps the closest analogy we have," says Gage. In the immune system, the ge...

Scientists show that tick-borne flaviviruses use a novel mechanism to evade host defenses

...ver, yellow fever and forms of encephalitis, evade immune system defenses in different ways depending on whe...efense against many viruses, triggers a cascade of immune defenses. According to researchers at NIAID's Rocky Mountain Laboratories (RML) in Hamilton, MT, NS5...

Researchers uncover E. coli's defense mechanism

...rains. Learning how the bacteria handle the body's immune response is the first step in developing more effective medicines. Spiro and colleagues focused their study on the NorR protein and the role it plays in reducing the levels of nitric oxide. In response to nitric oxide, NorR binds to DNA in order to ...

Engineered molecule amplifies body's immune response

...lecule called Stat1, which is involved in cellular immune signaling, scientists have succeeded in making the... defense against infection. Stat1 is involved in immune responses that are initiated by proteins called interferons. These proteins are produced by the cel...

Secrets to antibody's success against West Nile Virus surprise scientists

...mptom-free, but infections in people with weakened immune systems and those over 50 sometimes lead to seriou...rs to flag them for consumption and destruction by immune system cells known as macrophages. In the prior study, which screened several potential West Nile an...

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