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Tag: "immune" at biology news

Natural Killers Could Lead to New Hepatitis Treatments

... discovered that natural killer T (NKT) cells, the immune system's sentinels, patrol the labyrinthine blood ... new way of thinking about this important class of immune cell, which is responsible for the inflammation and cell death in the liver due to hepatitis. Hepati...

Chemists synthesize molecule that helps body battle cancers, malaria

...has been shown to significantly improve the body's immune response in vaccine therapies against aggressive d...cy of antigens introduced in the body to elicit an immune response, allowing for lower vaccine doses with greater effectiveness. The molecule could therefore ...

B cells are required for development of epithelial cancer associated with chronic inflammation

...ted against B lymphocytes or recruitment of innate immune cells toward premalignant tissue may represent a v...es have implicated an interaction between adaptive immune cells, like B lymphocytes, and innate immune cells during chronic inflammatory diseases. Dr. Lisa M....

Researchers test new therapy for advanced melanoma

...e testing a promising new therapy that prompts the immune system to aid in the fight against melanoma tumors... plasmid, which encodes a gene that stimulates the immune system, directly into the tumor site in mice. Then, they applied electroporation to the site to help...

Pair of cancer genes found to drive both cell migration and division

...thritis, since inflammation is caused when lots of immune cells move to one part of the body and cause it to swell painfully, he says. The researchers also hope their findings will provide a bridge between two scientific fields that have traditionally kept to themselves. "Scientists studying cell migratio...

Innovative coating could give medical implants a longer life

... make it very biocompatible and prevent evoking an immune response in the body." The researchers tested their coating on titanium dioxide (a material common in medical implants) in environments that simulated physiologic conditions with fresh serum and cells. The coating anchored itself firmly to the surfa...

Newly discovered protein an important tool for sleeping sickness research

...exceptional genetic strategy for evading the human immune system and resisting treatment, the current treatm...ent of the trypanosome's mechanism for evading the immune system. If the hypothesis is correct, it will bring scientists closer to developing a more effective...

Disabling gene defuses rheumatoid arthritis in mice

...s studying mice have identified a gene that allows immune cells known as neutrophils to protect themselves f...window for treating arthritic conditions caused by immune dysfunction. Currently, most treatments in development for these disorders focus either on preventin...

Breakthrough System for Understanding Ocean Plant Life Announced

...exceptional genetic strategy for evading the human immune system and resisting treatment, the current treatm...ent of the trypanosome's mechanism for evading the immune system. If the hypothesis is correct, it will bring scientists closer to developing a more effective...

Active Vaccine Prevents Mice From Developing Prion Disease

...nisms. In response to these proteins, the animal's immune system produces antibodies that will destroy them ...than through the skin, which localizes the initial immune response to the gut and mainly stimulates an antibody response, says Dr. Wisniewski. "By giving our ...

Researchers pioneer new gene therapy technique using natural repair process

...tions in the IL-2R gene are associated with a rare immune disease called severe combined immunodeficiency di...ly need to correct the defect in a small number of immune cells to fix the problem," said Dr. Porteus, assistant professor of pediatrics and biochemistry at U...

New vaccine means bye-bye to bacteria in the lung

...mice could be repeatedly given the vaccine and the immune response against P. aeruginosa was boosted. Usually, adenovirus vectors do not allow for repeated infection. These results may be useful in the development of vaccines against bacterial pathogens. The findings that a vaccine against Pseudomonas aeru...

NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma

...he promise of this therapy is that a patient's own immune system can be used to effectively treat existing t...e benefit from treatments based on using their own immune cells" said Mark Dudley, Ph.D., coauthor of the study. For more information about cancer, visit the ...

Survey reveals women and doctors aren't talking about HPV

...n, the virus is eliminated naturally by the body's immune system. But in some cases, the infection persists - sometimes staying dormant in the body months or even years before it becomes active, with the potential to cause cell changes in the cervix that can ultimately become cancerous. The Pap test can ide...

New understanding of cell movement may yield ways to brake cancer's spread

...ic cells move to the proper places to form organs, immune cells zero in to destroy pathogenic organisms, and...develop treatments that halt cancer metastasis and immune disorders like arthritis and asthma. "Previous studies by us and others have identified how a migra...

Cancer drug slows poxvirus in mice

... cell-to-cell spread of virus and allow the body's immune system to mount a successful defense, he explains. Experiments to test whether Gleevec might work against smallpox virus as well as against vaccinia virus are now being planned, Dr. Kalman says. "The approach of fighting disease by targeting drugs to...

Stem cell treatment improves mobility after spinal cord injury

...Keirstead and colleagues identified how the body's immune system attacks and destroys myelin during spinal c...e shown that when treated with antibodies to block immune system response, myelin is capable of regenerating, which ultimately restores sensory and motor acti...

Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine

...teria that cause the plague manage to outsmart the immune system and how, by slightly altering one of the mi...her infectious disease, uses to disable its host's immune system. "Yersinia pestis is the nastiest thing alive," said study author Olaf Schneewind, M.D., Ph....

Immune system's distress signal tells bacteria when to strike back

...c pathogen, Pseudomonas aeruginosa, has broken the immune system's code, report researchers from the Univers...detects interferon-gamma, a chemical messenger the immune system uses to coordinate its efforts to get rid of bacteria. When these bacteria intercept this mes...

MIT engineers an anti-cancer smart bomb

...urface chemistry allows the nanocells to evade the immune system, while their size (200 nanometers) makes them preferentially taken into the tumor. They are small enough to pass through tumor vessels, but too large for the pores of normal vessels. Once the nanocell is inside the tumor, its outer membrane d...

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