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Tag: "immune" at biology news

Same-Sex Mating Discovered in a Toxic Fungus

...transplant recipients and cancer patients -- whose immune systems are crippled by immunosuppressive drugs or chemotherapy -- and people with HIV/AIDS. The fungus' global importance as a health threat has therefore risen in parallel with the increased use of such therapies and with the worldwide HIV/AIDS pan...

Genetic defects give the immune system the green light to attack the pancreas

...nd genetic regions that, when defective, allow the immune system to attack the pancreas ?the first in a seri...by a process called immunological tolerance. These immune cells then attack the insulin-producing beta cells in the pancreas, mistaking them as foreign invade...

Biologists discover why 10% of Europeans are safe from HIV

... prevents the virus from entering the cells of the immune system but have been unable to account for the hig...fever that used the CCR5 as an entry port into the immune system. Using computer modeling, they demonstrated how this disease provided the selection pressure ...

Leprosy microbes lead scientists to immune discovery

...uman leprosy infections provide for study of human immune responses, scientists have discovered how the body's early warning system prompts a rapid immune response by two separate armies of defensive cells. The finding helps explain why, when threatened b...

First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes

... prevents the virus from entering the cells of the immune system but have been unable to account for the hig...fever that used the CCR5 as an entry port into the immune system. Using computer modeling, they demonstrated how this disease provided the selection pressure ...

Used in a new way, RNA interference permanently silences key breast cancer gene

...e is believed to interfere with the ability of key immune cells to attack a growing tumor. Investigators used the lentivirus to permanently insert the RNAi into the genome of the cancer cell. After a single exposure of this delivery system, they found 75 percent of laboratory breast cancer cells stopped ex...

Live vaccines more effective against horse herpes virus

...ne, employs a killed virus to activate the horse's immune response. Osterrieder vaccinated five horses with an MLV and five with an inactivated virus; five received no vaccination. None of the 15 horses was pregnant. The horses were then exposed to the herpes virus. The study found that the horses with ML...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

...he expression of inflammatory cytokine proteins by immune system cells must be finely tuned so that these proteins do not cause more damage to the body than the bacterial infection they were produced to defeat. Excessive inflammation can lead to organ failure and death, and this is exactly what happens when...

Turning viruses into allies against cancer

...modified herpes simplex virus, built with a potent immune stimulant to thwart the spread of cancer cells, is...colon stimulating factor). Its job is to induce an immune response to any surviving cancer cells released during the initial viral attack, essentially prevent...

Double triumph in stem cell quest

..., non-matching ESCs would be rejected by patients' immune systems unless they take immunosuppressant drugs. ...tions ranging from spinal injuries to an inherited immune condition. The work proves that matching ESCs can be derived via therapeutic cloning from donors of ...

Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.

...y role of the interactions between vibrios and the immune system of bivalves has been recently highlighted b...oth cellular and soluble components of the bivalve immune system in the light of the capacity of bacteria to evade the hemolymph bactericidal activity and to ...

MUHC scientists describe genetic resistance to rampant virus

...rigger fatal reactions in those with a compromised immune system, such as organ transplant recipients, newborns and persons infected with human immunodeficiency virus (HIV). Dr. Vidal believes her groundbreaking discovery increases the likelihood that therapies will be developed to fight CMV. ...

Plant Sacrifices Cells to Fight Invaders

...a gene essential to one of the plant kingdom's key immune responses--programmed cell death (PCD). Plants use... defense mechanisms, including PCD, are similar to immune responses exhibited by animal cells when they are fighting a disease-causing agent. In fact, PCD is...

A little stress gives beneficial oomph! to immune system

... evidence that a brief bout of stress can give the immune system a beneficial boost ?under certain condition...to hours ?temporarily mobilized all major types of immune cells, or leukocytes to potential battle stations in the body. In certain situations, this stress-in...

NIAID begins clinical trial of West Nile virus vaccine

...specially to older adults and people with weakened immune systems," says Anthony S. Fauci, M.D., director of... display them on their surface to alert the body's immune system--both helper T cells, which spur the production of antibodies to block the WNV from gaining e...

Defensins Ward Off HIV In Two Ways

...o protect itself from HIV infection via the innate immune system. Defensins are proteins found in cells, whi... viruses and therefore play important roles in the immune system. The researchers show that alpha-defensin-1 fights HIV in two different ways. Without serum ...

Protein prevents detrimental immune effects of bacterial sepsis

...rwhelming infection becomes uncontrolled. The very immune response meant to clear the pathogen and its toxin...es when it goes into overdrive, releasing too many immune signals. Thus, the immune response must be carefully controlled to prevent damage to the host. Dama...

UCLA scientists store materials in cells natural vaults

...mpatible with living cells and will not provoke an immune reaction. Previous efforts have relied upon viruse...urring capsules may prove less likely to elicit an immune response than foreign carriers like viruses. IMPACT: The UCLA discovery will enable many potential ...

Secret of smallpox's success may lead to bioterror cure

...ny ability to camouflage themselves from mammalian immune systems. The ability to stay hidden allows the sma...he point of causing devastating disease before the immune system detects it and attempts to mount a counter-attack. Jacobs notes that there have been clues t...

Gladstone investigators discover how resting T cells avoid HIV infection

...blood cells, that fight infection by orchestrating immune responses. They have the ability to recognize spec...d dividing, releasing cytokines (proteins that the immune system uses to communicate between cells) and recruiting and activating additional T cells. The new ...

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