Bioartificial kidney under study at MCG
...anging from regulating vitamin D to modulating the immune response. "Existing forms of dialysis have only re...lear and metabolize cytokines that help direct the immune system. The new device for kidney failure adds billions of kidney cells that can perform many of th...Viral DNA sequence a possible trigger for breast cancer
... The DNA sequence in question is usually found in immune cells and helps trigger the activation and proliferation of the cells. These sequences have also been found in proteins from some other cancer-causing viruses such as Epstein Barr virus and Kaposi's sarcoma virus, but what role this sequence plays in...Jump-starting T Cells In Skin Cancer
...at these vaccines work by increasing the number of immune cells called killer T cells that can attack the tumor. In an unexpected finding, however, they discovered that that these cells mostly recognize tumor proteins that were not contained in the vaccine. Understanding the characteristics of the T cell po...Spleen may be source of versatile stem cells
...onor mice -intended to train the diabetic animals' immune systems not to attackislet cells - were actually producing new islets. The result suggestedthat the adult spleen - previously regarded as playing a fairly minorrole in regenerative medicine - might contain a population of potentialislet stem cells.In...Source of molecular triggers in cutaneous T cell lymphoma identified
...ncy of T lymphocytes, the white blood cells of the immune system. Finding CTCL triggering factors has been a...ioning regulatory T (Treg) cells that suppress the immune responses of normal T cells to microbial agents. This may explain the susceptibility of patients wit...Dysentery uses 'sword and shield' to cause infection
...invade cells, while stopping any response from the immune system. They found that shigella was able to infe...ntery bacterium from being destroyed by the body's immune system. Dr Christoph Tang, from Imperial College London, and one of the researchers, comments: "Thi...Fox Chase Cancer Center scientists identify immune-system mutation
...ding the development of critical components of the immune system can contribute to medical advances in stimulating desirable immune responses and halting undesirable immune reactions, Kappes said. This understanding can further prog...Current human embryonic stem cell lines contaminated UCSD/Salk team finds
...r lowconcentrations of anti-Neu5Gc antibodies, the immune response wassignificantly reduced, but not completely eliminated.In their experiments, the researchers used recently developed probes todetect the presence of Neu5Gc on the cell surface of human embryonicstem cells that had been grown in traditional ...Elusive HIV shape change revealed; Key clue to how virus infects cells
...g the virus to bind to and enter a cell before the immune system can "see" it, notes Harrison. "We can now compare the bound and unbound forms and try to understand whether there are any immunologic properties that differ and that might provide a route to new vaccine or drug strategies," Harrison says. ...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
...lp mediate the amoeba's ability to evade the human immune system. This could explain why the parasite can st... help researchers find better means to harness the immune system to eradicate infection through vaccine development. A number of the metabolic adaptations an...Novel antiviral technology inhibits RSV infection in mice
...ngchildren, the elderly and those with compromised immune systems. Novaccine or widespread antiviral treatment is available for theinfection. Researchersat USF's Joy McCann Culverhouse Airway Disease Research Center, workingwith scientists from the Moffitt Cancer Center and TransGenexNanobiotech Inc., used...Newly discovered virus linked to childhood lung disorders and Kawasaki disease
...d spring; recent studies have described a powerful immune response inthe respiratory tract and other organs in acute cases of Kawasakidisease, suggesting the involvement of a specific microbe, which mayenter the body through the respiratory tract; finally, as the emergenceof SARS illustrates, coronaviruses ...Inflammatory molecules released by pollen trigger allergies
... are released from pollen. These molecules bind to immune cells and cause them to launch a typical allergy-promoting immune response. Pollen from plants exposed to air pollutants produce more of these allergy-provoking compo...Genome-wide mouse study yields link to human leukemia
...natural killer cells, both major components of the immune system. In comparing the mice in the pre-leukemic stage and those with ALL with normal mice, researchers found that methylation, a chemical process that adds methyl molecules to DNA, silenced a number of genes ?but only in the mice with full-blown A...NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis
...niversity biologists have uncovered how the innate immune system in mice's brains fights viral infection of ...However, these findings show the redundancy of the immune system--when one response fails to fight infection, others step in." The study was also conducted a...Live Recombinant Adenovirus Vaccine Technique Explored
...eplicated in the body and thereby create a lasting immune response. The researchers inserted the L1 gene into a live adenovirus such that it would be expressed using the virus' own late-gene expression machinery. L1 is expressed at very high levels in some recombinants. Dr. Ketner believes that the replica...Leukemia Drug Breakthrough Study In New England Journal Of Medicine
...rish tumors (anti-angiogenesis) and stimulates the immune system to fight cancer cells. The study is reported in the Feb.10 issue of the New England Journal of Medicine. Nearly 90 percent of MDS patients are anemic and require regular transfusions of red cells. In this study, 91 percent of the MDS patients...Jefferson Virologists Coax HIV Out of Hiding
...ty ?of replicatingand wreaking havoc on the body’s immune system.Now, virologists at Jefferson Medical Colle...to bring HIV out ofhiding. They have shown that an immune cell protein calledinterleukin-7 (IL-7) can rouse the virus better than previously triedagents, maki...Novel Therapy Tested in Mice Could Chase Away Cat Allergies
...r dander (small scales from its skin or hair), key immune system cells respond by spewing out histamine. All...ults suggested that GFD successfully prevented the immune cells from reacting to cat allergen. The next step was to test GFD in mice that we had made allergic......de two importantdiscoveries: New blood vessels and immune system cells may be essentialto the initial format...urrounded by bloodvessels and microglia, which are immune system cells in the brain. Butit was unclear whether the development of blood vessels and recruitmen...