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Tag: "image" at biology news

The synapse is a shotgun

...dence for a different concept of the synapse. "The image of this ganglion is not one of a simple synapse with a single release site, but multiple release sites. And it shows alpha 3 receptors within the postsynaptic region, but alpha 7 receptors outside this region. Our model showed that if we assumed that...

Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease

...ia with the patient awake. First, MRI was used to image the target subthalamic nucleus (STN) region of the brain. The STN was mapped using microelectrodes by recording from single neurons as the electrode was slowly moved towards the STN. Once a signature firing pattern was obtained confirming that the ...

'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes

...ts would then be shown either another square or an image of a monkey looking either left or right. Immediat...ary eye movements in the same direction the monkey image was looking, found Deaner and Platt. Also importantly, said Platt, the shift in attention was very ...

Most common lung cancers may begin in newly discovered cells

...group to develop microscopic fluorescent probes to image the unique molecular surface of BASCs and track the progress of the naturally arising tumor, Jacks said. The similar genetic activity profile of mouse tumors with K-ras mutations to the profile of human lung cancer samples make the researchers optimi...

Microscopic brain imaging in the palm of your hand

...e Optical Society of America. Researchers want to image individual cells inside living subjects because it... often use some form of fluorescence microscopy to image tissue. In conventional "one-photon" fluorescence imaging, the scientist injects a dye into tissue a...

Researchers seek to discover what really happens when a virus enters the body

... the electrical engineering concepts of signal and image processing. As Duca, a biophysicist, introduces vi...includes the spurious artifacts that appear in the image due to the microscope's uneven source illumination. Noise can also result from the spectral overlap ...

New tool reveals secrets of migrating cells

...can be sharply imaged and stacked to produce a 3-D image of the cells in real time. The system they use employs an infrared laser emitting short intense pulses of 920 nanometer-wavelength light. In the thymus, it's possible to view cells 400 microns inside the cortex, which is about 4/10 of a millimeter o...

Brown-Harvard team solves mobile DNA's surgical sleight-of-hand

...ticated computer software, to create a 3-D digital image of λ-INT caught in the act of carrying out site-specific recombination. In complementary experiments carried out at Brown and published recently in the Proceedings of the National Academy of Sciences, Radman-Livaja tagged bits of lambda DNA with dye...

Mosaic mouse technique offers a powerful new tool to study diseases and genetics

...actually study the tumor's progression. If you can image these cells in a live animal, you can potentially watch the tumor grow." Luo points out that MADM is more precise than the widely used "knockout mouse" technique, in which a gene of interest is removed ("knocked out") of every cell in the animal's b...

A probe, not an echo

...oadcast into the tissue, and the echoes produce an image of the reflecting interfaces ?that is, the sound t...spended in water), creating a stack of tomographic image slices which visualization algorithms turn into 3D images. In the first set of experiments using th...

Duke engineers develop new 3-D cardiac imaging probe

...time it takes for current ultrasound technology to image a single heart cross section. The new probe has c...chers said. The new Duke probe can also be used to image the esophagus, rectum, colon and prostate. A peer-reviewed report on the work was published this mo...

Scientists discover how plants disarm the toxic effects of excessive sunlight

... absorb solar energy. The following NASA satellite image maps chlorophyll concentrations on land as well as in oceans, lakes and seas. This image provides a snapshot of photosynthetic capacity and significant sources of singlet oxygen, a toxic by...

Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert

...ally identify biological materials from a standard image captured by the rover. Taken together, these four pieces of evidence are strong indicators of life," said Waggoner. "Now, our findings are being confirmed in the lab. Samples collected in the Atacama were examined, and scientists found that they cont...

Use of PET can reduce, may eliminate more strenuous drug development trials with animals

... was developed and is used in much the same way to image small animals. Small animals, especially mice, play a fundamental in the study of human biology and disease. Mice have nearly the same set of genes as humans, offering an opportunity to learn about the function of the many genes shared by both. This...

Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin

... surface of a polymersome, a cell-like vesicle, to image a tumor within a living rodent. Their findings, wh... the polymersome membrane can be used to optically image tissue structures deep below the skin ?with the potential to go even deeper," said Michael J. Therie...

Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals

...e off a distinctly different signal. The resulting image reveals dark areas that indicate the presence of t...expressed," Ahrens said. Existing methods used to image gene expression have limitations, according to Ahrens. Some methods cannot be used in living subject...

Devising Nano Vision for an Optical Microscope

...version of the optical microscope might be able to image and measure features smaller than 10 nanometers—a ...iolet light with a wavelength of 436 nanometers to image features as small as 40 nanometers, about five times smaller than possible with a conventional optic...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

...c force microscopes use a sharp microscopic tip to image surfaces and detect energy differences by mechanically probing molecular surfaces. In a poster presentation at the American Chemical Society's annual meeting, the researchers will describe the first biophysical analysis of interactions between monom...

New Breast Cancer Test Could Save Lives

...eliable. This latest technology has the ability to image through dense breast tissue, and therefore can reach a far wider section of women than X-ray mammography can. Women below 50 in particular will benefit from this new test, which is much more reliable than X-rays at detecting cancer in this age group...

Nano-Probes Allow an Inside Look at Cell Nuclei

...Our work represents the first time a biologist can image long-term phenomena within the nuclei of living cells," says Fanqing Chen of Berkeley Lab's Life Sciences Division, who developed the technique with Daniele Gerion of Lawrence Livermore National Laboratory. Their success lies in specially prepared c...

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