Tearing down the fungal cell wall
... cell wall biosynthesis. Future work will focus on identifying the role of the product of the AbNPS2 gene which should allow us to get an important handle on the precise series of molecular events that give rise to these drastic effects on spore viability." ...Ocean sampling yields environmental sources of coral symbionts
... In the new work, the researchers succeeded in identifying Symbiodinium in the water column as well as on ocean-bottom substrates. Most importantly, the researchers also demonstrated that a subset of Symbiodinium found in the water and on benthic substrates (that is, on algae and sediments) can infect new co...New research identifies gene important for nicotine's effects on the brain
... nicotine-related behaviors," said Picciotto. "By identifying molecules and changing their activity we can understand how overall behavior is changed. " Picciotto's work explored how the brain changes when it receives nicotine and, therefore, focused on the dopamine system in the brain. Dopamine is one of a ...RNA map provides first comprehensive understanding of alternative splicing
... cancers. Since then the laboratory has focused on identifying RNA sequences -- and in particular, identifying alternatively spliced pre-mRNAs -- that Nova binds to. In the last three years, in work published in...First major study of mammalian 'disorderly' proteins
...s of cells. The new technique for collecting and identifying IUPs is important because although scientists have been aware of the existence of flexible proteins for many years, they have only recently realized that these molecules play major biological roles in the cell, according to Richard Kriwacki, Ph.D., a...Lab-on-a-chip could speed up treatment of drug-resistant pneumonia
...e the patients' lives, Lochhead said. But reliably identifying the bacterial strain that's causing the infection ...any also hopes to apply the technology not just to identifying known strains but also to testing the efficacy of new drugs, or of existing drugs on unknown strains...Distinguishing friend from foe in the battle against cancer
...Cell Biology Laboratory. "We've made huge progress identifying specific events that change normal proteins into proteins that cause cancer and developing drugs that target those proteins. This work provides another potential direct target for development of cancer drugs." The Hunter lab previously showed that ...Leading reason for corneal transplants comes into focus
...sed not only linkage analysis but also a method of identifying variations in DNA sequences to examine three FCD families in which 43 members had the disease and 33 did not. He and his coworkers were able to narrow down the linked traits in all three families to the short arm of chromosome 18 (the whole "address"...Protein 'fingerprint' in spinal fluid could spot Alzheimer's disease
...med that the panel is over 90 percent sensitive in identifying people with Alzheimer's disease," says Kelvin Lee,...ht not point to Alzheimer's but together formed an identifying pattern or "fingerprint" specific to the illness. "Although it need not have turned out that way,...For Pacific white shrimp, gender matters when competing for food
...owing demand for shrimp and shrimp-based products, identifying shrimp that grow more efficiently will be an important tool to maximizing production. ...New tool helps blood specialists improve patient care
...ractice. "We commend ASH for their leadership in identifying these performance measures to improve the quality of care hematologists provide to their patients," said Christine Cassel, MD, President and CEO of ABIM. "By completing the Hematology PIM, physicians have a convenient and effective way to earn points...Hope for major advance in fighting world killer disease
... in four hospitals in India, will offer a means of identifying the two most deadly forms of the disease quickly, cheaply and with little training necessary for practitioners. The implications for improving children's health could be enormous. Diarrhoea is a major killer in developing countries. World Hea...Resistance and genetic sensitivity to sleeping sickness
...edge about host-parasite interactions, by means of identifying genetic markers signalling risk. That should open the way in the long term to possible development of innovative control strategies against sleeping sickness. ...New dyslexia theory blames 'noise'
... they struggle to form solid mental categories for identifying letters and word sounds. Such children may benefit from intensive training under "noisy" conditions to strengthen their mental templates, said University of Southern California neuroscientist Zhong-Lin Lu. Lu was a co-author on three studies,...Experimental vaccine protects mice against deadly 1918 flu virus
...enza virus. They also have created a technique for identifying antibodies that neutralize this virus, a tool that...d had no effect. This method was also effective in identifying neutralizing antibodies to the H5N1 avian flu virus and could be used to screen for monoclonal antib...Gene chip technology shows potential for identifying life-threatening blood infection
...hours after the onset of sickness with the goal of identifying all the genes that might be markers of inflammation and infection. They found small increases in gene expression among hundreds of genes, but it was not the magnitude of change in gene expression that accurately distinguished sepsis from systemic inf...Researchers map spread of pathogens in the human body
...stigations have been hampered by the difficulty of identifying and observing directly the infection process within live tissues. For this study, the Cambridge researchers used advanced fluorescence microscopy techniques to observe intracellular growth of Salmonella bacteria within living cells....St. Jude finds clues to hearing loss from chemotherapy
...ook the first step toward these ambitious goals by identifying 17 families of mice whose offspring carry one or more of a variety of mutations that cause them to lose the ability to hear high-frequency sounds, according to Jian Zuo, Ph.D., associate member of the St. Jude Department of Developmental Neurobiology...International team analyzes human genetic variation in key immune region
...e tools needed to begin the initial efforts toward identifying genetic risk factors in the MHC for common immune-mediated diseases. Such endeavors, involving researchers at the Montreal Heart Institute, the University of California, San Francisco and the Broad Institute of MIT and Harvard, are now underway for s...Second opinion yields treatment changes for half of patients
...g results in 45 percent of patients, in some cases identifying previously undiagnosed second cancers. More than a quarter of patients were recommended to undergo another biopsy. Previous studies have documented variation in how radiologists interpret mammograms. Those who specialize in breast imaging tend to det...