Stem cell transplants explored at Stanford as a possible treatment for hearing loss
... Heller gained international attention in 2003 for identifying stem cells that reside within the inner ear. Since then, his research has focused on using these stem cells to regenerate the critically needed hair cells in the inner ear. Later in 2003, his group reached another significant milestone: the team ...Researchers discover genetic cause for word-finding disease
... not just what causes the disease but the uniquely identifying features of human language. That's a pretty big question," added Mesulam. MRI imaging of the brains of people with PPA shows the language part in the perisylvian region of the left hemisphere has shrunk. By comparison, Alzheimer's Disease targets...Lab research may one day lead to cancer treatment using patient's own immune cells
...ues in the laboratory at this stage, will focus on identifying and harvesting T cells within the lymph nodes of patients, activating these T cells and growing them in culture in the laboratory over one to two weeks. The T cells are activated with molecular agents called interleukin-2 and anti-CD3 antibody (OKT3...Susceptibility to Crohn's disease -- an important new clue
...mbination of environmental and genetic factors and identifying these genetic risk factors is one of the most important objectives of modern medical genetics, potentially paving the way towards personalized medicine and drug target identification. ...Largest genomic search finds genes that may contribute to autism
... expertise in an effort to speed up the process of identifying susceptibility genes, those that heighten a child'...lutamate is known to be involved in learning. By identifying this gene it begins to allow researchers "to go from gene to brain to behavior in a way we haven't g...Scientists discover new virus caused deaths of transplant recipients from single donor
...urn up leads," stated Dr. Lipkin. "We succeeded in identifying the virus responsible for the deaths by building on their work and utilizing new tools for pathogen surveillance and discovery developed in the Greene Laboratory and 454 Life Sciences." ...Using dental X-rays to detect osteoporosis
...r Dentistry Amsterdam have created a unique way of identifying patients at risk of osteoporosis by using ordinary dental x-rays. Professor Paul F. van der Stelt and his team developed the largely automated approach to detecting the disease during a three-year, EU-funded collaboration with the Universities of Man...Tiny clue reveals new path toward heart disease
...que in the vessels to the heart. In addition to identifying the genetic variations in the kalirin gene, the researchers also identified two genes that are involved in the same biological pathway, known as the Rho-GTPase signal transduction pathway. ...Neural bottleneck found that thwarts multi-tasking
...these regions. While fMRI is an excellent tool for identifying a particular area in the brain involved in a given task, it generally provides limited information about how that area responds over time. To overcome this limitation, Dux and Marois rapidly sampled brain activity using fMRI while subjects were p...MIT biologists solve vitamin puzzle
...se taught by Walker resulted in a novel method for identifying mutant strains of a soil microbe that could not form a symbiotic relationship with a plant. Walker's team has now found that one such mutant has a defective form of an enzyme known as BluB that leaves it unable to synthesize B12. BluB catalyzes...Scripps Research study reveals new activation mechanism for pain sensing channel
...nding of these compounds activate the channel, and identifying the physiological role of TRPA1 in sensing oxidative stress." The protein is currently being investigated by several pharmaceutical companies as a potential target for chronic pain, Patapoutian noted. ...Cracking open the black box of autoimmune disease
...s. It verified that we were on the right track for identifying autoimmune related genes." The researchers still don't know exactly how Foxp3 enables regulatory T cells to prevent autoimmunity. But the list of the genes that Foxp3 targets provides an initial map of the circuitry of these cells, which is import...CSHL research ties harmless viruses to cancer
...ancer is its prevention. If viruses can cause CIN, identifying and inactivating these viruses would help to decrease the incidence of the disease. This prognosis is consistent with the successes of preventative immunization against hepatitis B and papilloma viruses, which both cause cancer. Lazebnik and his CSHL...Reactivated gene shrinks tumors
..., but they have started trying to figure it out by identifying the other genes that are activated in each type of tumor when p53 turns back on. The study also revealed that turning on p53 has no damaging effects in normal cells. The researchers had worried that p53 would kill normal cells because it had never...Fruit fly gene research may shed light on human disease processes
... Now, he and Avila have made another breakthrough, identifying a signaling pathway outside the cell that helps trigger a cascade of proteins to ensure embryos remain either male or female once their sex has been determined, as well as help in the chromosome-counting process and in regulating other crucial cell a...Chromosomal microarray analysis proves accurate
...ases." He said the technique does not help with identifying the problem in all children, but there is a five t...test, and the newer version was more successful in identifying chromosomal abnormalities. The targeted microarray analysis used here is essentially a gene chip ...Endangered shortnose sturgeon saved in Hudson River
...in. Since 1966 when the federal government started identifying threatened species, only 16, including the American alligator, American peregrine falcon and brown pelican, have recovered. "Recovery is very rare," said Bain, who has been monitoring the shortnose sturgeon's population since the mid-1990s and has ac...Molecular atlas provides new tool for understanding estrogen-fueled breast cancer
...standing the role of estrogen in breast cancer. By identifying genes associated with the ER in breast tumors, it opens up previously unexplored regions of the genome involved in the estrogen-dependence of breast cancer." The knowledge may one day help researchers and physicians determine which treatments are l...Solution to bacterial mystery promises new drugs
... mystery," Rock said. "It's also important because identifying the essential components required for disease-causing bacteria to grow and multiply is a key part of developing new strategies for controlling infections." ...... genetic subtypes of the disorder, but progress in identifying the exact genes responsible has been slow because groups of families inherit different susceptibility genes. The Slynar gene is normally found in the brain, but in bipolar disorder has an abnormal effect due to mutations in the gene. However, res...