Risk of HIV transmission highest early in infection
...screening. Hence, we must do a much better job of identifying recently infected people if we are to be able to counsel them to modify high-risk sexual behavior and desist from transmitting the virus.? He suggested the development of affordable tests such as polymerase chain reaction assays to directly monitor...Beyond the DNA: Chemical signatures reveal genetic switches in the genome
...SD) School of Medicine have made a breakthrough in identifying functional elements in the human genome, according to a report published online today in Nature Genetics. While the DNA sequence can identify genes (the 'what') within the genome, it cannot answer the more fundamental questions of 'how,' 'when' and...Mine runoff continues to provide clues to microbial diversification
...rganisms are doing in their natural environment by identifying the range of proteins that they produce. The techn...o its Genomes to Life program, which is focused on identifying and characterizing the molecular machines of life. This study helps extend the initial studies of mi...Researchers learn what sparks plant growth
...s lab. Chory’s research group is interested in identifying the mechanisms by which plants alter their shape and size in response to changes in their environment. Chory studies Arabidopsis, a member of the mustard family that is to plant biologists what the mouse is to mammalian geneticists. "How do organi...Scripps research study shows humans and plants share common regulatory pathway
...derstanding of the regulatory pathways of Nod1. By identifying SGT1 as a positive regulatory protein, our study offers new insights into the entire family." SGT1 is a protein found in yeasts, plants, and mammals in both the nucleus and the cytosol. It functions in several biological processes through interact...Brown cancer biologists identify major player in cell growth
... cancer. So biologists are keenly interested in identifying the accelerators that rev-up cell division. Ets transcription factors, a family of gene-regulating proteins that are major players in embryonic and cancer development, seemed obvious culprits. Rosmarin, a hematologist-oncologist, studies one member o...New details on how the immune system recognizes influenza
...pitopes. Further analyses may assist scientists in identifying vaccine targets that might offer broader protectio... researchers say more studies should be focused on identifying human T and B cell epitopes from human and avian strains of influenza virus--especially those associ...Bacterial walls come tumbling down
...died. Although scientists have spent many years identifying bacterial components whose structural features might have weaknesses that can be exploited by antibiotics, progress in turning up bona fide drug targets has been slow. The cell wall enzymes in particular have tantalized scientists, Strynadka said. "T...Sheffield scientists light up bacteria
..., whether accidental or deliberate. Currently identifying bacterial infection takes several days and requires swabbing and culturing of bacterial swabs as well as the use of specialist bacteriology laboratory facilities. By combining polymers, which change shape when they encounter bacteria, and developing ...Analysis of rhesus monkey genome uncovers genetic differences with humans, chimps
... with the genomes of other organisms is crucial to identifying what makes the human genome unique." The rhesus, because of its response to the simian immunodeficiency virus (SIV), is widely recognized as the best animal model for human immunodeficiency virus (HIV) infection. The rhesus genome sequence will a...New protein inhibitor impedes growth of cancerous cells
...ormal roles of Plk1 in new detail, and potentially identifying specific cellular processes that might be targeted by future anti-cancer therapeutics. ...New species of snapper discovered in Brazil
...dy published in Zootaxa provides a revised key for identifying all Lutjanus species in the western Atlantic, along with evidence that the new species completes its life cycle in different but interdependent marine habitats such as coral reefs and mangroves. "This discovery that a large, popular fish is a spec...Autism gene identified by researchers at Yale working with a global research consortium
... share their samples, data and expertise to aid in identifying autism susceptibility genes. Funded by Autism Speaks, a national non-profit dedicated to increasing awareness of autism and raising money to research the disorder, and the National Institutes of Health, these are the preliminary findings from the...Insomnia drug can improve brain function
...single patient trials can be a logical approach to identifying potentially beneficial drugs, especially in the case of rare or orphan diseases. ...Infection detectives use disease 'fingerprints' to track common infections in children
...western Medical Center have found a new method for identifying suspect viruses and bacteria that cause some of th...and Children’s. It could also prove useful for identifying previously unknown illnesses or biological weapons. "Even if we don’t know which pathogen it is, ...Genes and biomarkers that allow doctors to choose the right therapy for the right patient
...ts for women, and their methodologies could aid in identifying similar biomarkers for responses to other drugs and for other types of cancer. "Individuals respond differently to different therapeutics because there are substantial differences in the spectrum of genetic, biological and epigenetic characteristi...Canada's new government invests $200M in the fight against the mountain pine beetle
...e program will also assist affected communities in identifying new forest products, markets, industries and services to help ensure their long-term economic well-being. The Government of Canada recognizes that the forest industry is an important contributor to the Canadian economy and that it has been facing ...Selective marker found to indicate aggressive form of breast cancer
...in to a particularly deadly form of breast cancer, identifying a new biomarker that could lead to earlier detection and better treatment. In the January 15 issue of Cancer Research, researchers from Dartmouth Medical School demonstrate that nestin could represent a selective biological marker for basal epithel...Xie Lab demonstrates the role of microRNA pathway
... expansion in vitro." "We are in the process of identifying the microRNAs that are important for stem cell self-renewal," said Dr. Xie. "Understanding the mechanisms controlling stem cell self-renewal will be crucial to our developing the ability to expand stem cell populations for performing tissue repair." ...Scientists create dual-modality microbeads to improve identification of disease biomarkers
...l be to detect cancer and neurological diseases by identifying certain molecules present in human blood or urine that indicate specific diseases, according to Nie, who is also professor of biomedical engineering, chemistry, materials science & engineering, and hematology and oncology at Emory University and ...