Genetic factors are linked to fever following smallpox vaccination
...s,” Dr. Stanley remarked. “Our work is designed to identify ways we might make vaccines even more acceptable in the future by discovering ways to further reduce the chance of minor adverse events.” In an accompanying editorial, James E. Crowe Jr., MD, of Vanderbilt University Medical Center, echoes Dr. S...Could fungal collection hold the key to new life-saving drugs?
...s from filamentous fungi which will be screened to identify pharmaceutically active compounds, which could potentially be developed into drugs. Joan Kelley, Executive Director Bioservices, CABI said: “This is a really exciting collaboration and we are looking forward to working with the expertise of the...New findings challenge established views on human genome
...could have significant implications for efforts to identify the DNA sequences involved in many human diseases....earn how to read the manual’s language so they can identify every part and understand how the parts work together to contribute to health and disease. In re...Penn researchers link cell's protein recycling systems
... Huntington’s disease. They are also attempting to identify pharmacologic approaches to augmenting HDAC6 activity....454 sequencing identifies HIV drug resistance at early stage
...ave used the company’s Genome Sequencer™ system to identify previously undetectable rare drug resistant HIV variants in samples from an earlier performed clinical trial. The work, presented today by Michael Kozal, M.D. of the Yale University School of Medicine and the VA CT Health Care System, was a blinded-...Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
...nd Pharmacy, used cell surface markers and dyes to identify cancer stem cells as well as normal adult stem cells and their progeny in samples obtained from normal lung and lung cancer tissue samples. The researchers identified a very small, rare set of resting cancer stem cells in the lung cancer samples that...Marine phytoplankton changes form to protect itself from different predators
...chemically sense the presence of nearby consumers, identify those consumers and change in opposing ways depending on which consumers are present.” The behavior could have implications for global climate change because Phaeocystis blooms play a key role in the carbon cycle of cold oceans, accounting for up ...Research finds that circadian rhythms dominate all life functions
...uses advanced algorithms that have the capacity to identify patterns in such a large number of genes. Ptitsyn discovered that gene activity oscillates in a "finely orchestrated" system and gene expression can be impacted by daylight and darkness -- or a lack of both. For example, while gene expression osci...Gene responsible for common hearing loss identified for first time
...we were able to conclude that we were the first to identify a gene that influences the susceptibility for otosclerosis”, said Ms Thys. “And, as further evidence, we were also able to show that a more active variant of this gene is protective against the disease.”......f base pairs determined in detail – scientists can identify locations in individual mice where the jumping genes have carried pieces of loxP DNA. Then, they can select a mouse with loxP on both sides of the large piece of DNA they want to mutate and study. If the jumping gene carrying loxP hops into the m...Weizmann Institute scientists develop a general 'control switch' for protein activity
...ond stage, the engineered proteins are screened to identify the ones that respond to the drug in a desired manner. The researchers have discovered that in some of the engineered proteins the drug increased the activity level, while in others this activity was reduced. Says Prof. Liscovitch: “We were surpris...Scientists close in on missing carbon sink
...his will help us better predict climate change and identify possible strategies for mitigating it." The missing carbon For years, one of the biggest mysteries in climate science has been the question of what ultimately happens to the carbon emitted by motor vehicles, factories, deforestation, and othe...Understanding why C. difficile causes disease -- it's hungry
...nshein and his colleagues are currently working to identify a protein that might shut down the gene that codes for R. By identifying such a protein, Sonenshein hope to find a way to change the appetite of the bacteria. "If we find a way to shut down toxin production in the hypervirulent strain, we might have ...Ants show us how to make super-highways
... pothole – jarring every bone in their body – will identify with this story. When it comes to rapid road repairs, the ants have their own do-it-yourself highways agency." "When the traffic has passed, the down-trodden ants climb out of the potholes and follow their nest mates home," added Powell. "Broadly...Focused ultrasound relieves fibroid symptoms in women
...ds. The women received pre-treatment MR imaging to identify and define the target fibroids. Radiologists then used MRgFUS to locate and treat the targeted fibroids while monitoring temperature changes in tissue. Ninety-six patients were treated under the original study protocol (A), and 64 patients were ...Extra-aggressive form of idiopathic pulmonary fibrosis identified
...liminary, these results may allow investigators to identify biomarkers of disease progression," said Dr King, who is the Chief of Medicine at San Francisco General Hospital and an internationally renowned expert in research and management of pulmonary fibrosis. The senior author on this paper, Dr Naftali...Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients
...liminary, these results may allow investigators to identify biomarkers of disease progression and, more importantly, better evaluate the effectiveness of potential therapies," added Talmadge E. King Jr., M.D., chief of medicine at San Francisco General Hospital and an internationally renowned expert in resear...Scientists discover 5 new species of sea slugs from the Tropical Eastern Pacific
...Hermosillo and her collaborators two more years to identify the animals in the new collection by comparing them to existing collections, consulting specialists and using a scanning electron microscope to examine the jaws and other hard parts of the nudibranchs that distinguish species. This was part of the...Technique monitors thousands of molecules simultaneously
...ns, he and his collaborators are working to better identify the molecules they make on the chips, and perfect the signaling techniques used to monitor molecules on the chips. He praised the time-of-flight secondary-ion-mass spectrometry work of his Washington University colleague Amy Walker, Ph.D., assistant ......ture. "Based on these findings, we were able to identify this element as a kind of chromatin insulator that...ancers and promoters. The group is also working to identify any additional proteins that may play a role in establishing the insulator. Knowing what genes th...