Customized gene chip provides rapid detection of genetic changes in children's cancer
...en's Hospital of Philadelphia. "As future research identifies other genes active in neuroblastoma, we can modify...nformation to RNA, the current microarray directly identifies changes in DNA. "These DNA changes, involving gain or loss of genetic material, are important for ne...Chernobyl: The true scale of the accident
...nstrated radiation levels can justify. The report identifies the need to sharpen priorities and streamline the programs to target the most needy, noting that reallocating resources is likely to face "strong resistance from vested interests". One suggestion calls for a "buy out" of the entitlement to benefits i......ational HIV treatment guidelines This study also identifies some of the main reasons why many physicians may be reluctant to prescribe a treatment of proven efficacy and safety. The reasons include; the physicians' perception that patients would be reluctant to use a self-injectable therapy, the physicians' o...Report focuses on challenges to unlocking future promise of vaccines
...reating and applying vaccines. The report identifies over 40 infectious agents that pose significant hu... effective vaccines. In addition, the report also identifies a number of infectious agents that are relatively rare today, but are poised to emerge by either nat...PET imaging reveals the immune system at work
...mmune diseases, where the immune system mistakenly identifies native cells or tissues as foreign and mounts an attack. The techniques they've developed should now enable scientists -- and one day clinicians -- to observe the ebb and flow of the immune system over the course of an episode of disease or autoimmu...Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method
...mmune diseases, where the immune system mistakenly identifies native cells or tissues as foreign and mounts an attack. The techniques they've developed should now enable scientists -- and one day clinicians -- to observe the ebb and flow of the immune system over the course of an episode of disease or autoimmu...Gene increases risk of tuberculosis
...r 19 issue of The Journal of Experimental Medicine identifies a small genetic change that increases the odds of developing active tuberculosis (TB). Pedro Flores-Villanueva and his colleagues at the University of Texas Health Center (Tyler, TX) studied groups of patients in Mexico and Korea and found that indi...New study pinpoints epicenters of Earth's imminent extinctions
...nction (AZE –? www.zeroextinction.org ), the study identifies 794 species threatened with imminent extinction, each of which is in need of urgent conservation action at a single remaining site on Earth. The study found that just one-third of the sites are known to have legal protection, and most are surrounded...Pretreating rogue cancer cells with aspirin cripples their resistance to targeted therapy
...nction (AZE –? www.zeroextinction.org ), the study identifies 794 species threatened with imminent extinction, each of which is in need of urgent conservation action at a single remaining site on Earth. The study found that just one-third of the sites are known to have legal protection, and most are surrounded...Twin molecular scissors link creation of microRNAs with gene-silencing
...the two single-stranded miRNAs from each other and identifies and holds one as a guide to help it find the specific messenger RNA to be inactivated. Using complementarity to match the guide miRNA to a particular length of its target messenger RNA, Dicer and TRBP then hand over the messenger RNA for cutting by A...Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool
...alysis -- a multimillion-dollar-a-year industry -- identifies gene activation in living, complex biological systems. DNA microarrays monitor the behavior of thousands of genes over time by detecting changes in the expression of as many as 30,000 different genes on one small chip. The technique has been used to ...New book on rain forests, slash-and-burn agriculture
...rth's biodiversity and climate. The new book also identifies the costs and benefits of alternative uses of forests and cleared land in several benchmark sites throughout the developing world. It is based on the first decade of work by the Alternatives to Slash-and-Burn consortium, which was formed in 1992 by a...Scientists develop protein-sequence analysis tool
... CPDL for "conserved property difference locator," identifies positions where two related groups of proteins differ either in amino acid identity or in a property such as charge or polarity. "Experience tells us that such positions are likely to be biologically important for defining the specific functions of ...Birth defects: 8 million annually worldwide
...ntries and those with higher incomes. "Our report identifies for the first time the severe, and previously hidden global toll of birth defects," explains Dr. Jennifer L. Howse, president of the March of Dimes. "This is a serious, vastly unappreciated and under-funded public health problem." "The human toll o...Simple idea to dramatically improve dengue vaccinations
...rget infection. This starts when the immune system identifies infected cells and brings pieces of them into the ...nal. Through a complex trial-and-error process, it identifies three to five T-cells that best recognize and attack the components of the sickened cells. Once the ...Aggression-related gene weakens brain's impulse control circuits
... under-active impulse control circuitry. The study identifies neural mechanisms by which this gene likely contributes to risk for violent and impulsive behavior through effects on the developing brain. NIMH intramural researchers Andreas Meyer-Lindenberg, M.D., Ph.D, Daniel Weinberger, M.D., and colleagues r...A new focus for the mechanism of nerve growth
... are just beginning to be understood and this work identifies a new role for them. The researchers, led by Paul Forscher , professor of molecular, cellular and developmental biology at Yale used a technique called fluorescent speckle microscopy, or FSM, that let them directly see actin filament assembly, d...'Genetic network' guards against lethal DNA damage
...LAM technology takes advantage of DNA barcode that identifies which genes a yeast cell is missing. This is much like using a commercial barcode in a store to quickly identify items at the checkout counter. The scanner in this case is a microarray: a grid of thousands of spots on a piece of glass that holds a un...UF scientists trace origin of shark's electric sense
...he current edition of Evolution & Development, identifies neural crest cells, which are common in vertebrate development, as a source of sharks' electrical ESP. It also fortifies the idea that before our early ancestors emerged from the sea, they too had the ability to detect electric fields. "Sharks have......match," said van der Lelie, "then the tag probably identifies a brand new species, which is also very interesting!" In another test with possible applications for identifying agents used in bioterror attacks, the technique also clearly discriminated between closely related strains of Bacillus cereus, a pathoge...