identifies 2 2

Tag: "identifies" at biology news

Eliminate Data Analysis Bottlenecks in Drug Discovery

...n the glucose-making process, but the new research identifies a critical regulatory step the researchers say could be targeted as well. PGC1, which Puigserver isolated and cloned in 1998 as a postdoctoral fellow at Harvard, controls gene expression in the liver and other tissues. In the liver, it triggers the ...

B cells are required for development of epithelial cancer associated with chronic inflammation

...ch study published in the May issue of Cancer Cell identifies B lymphocytes as important regulators of premalignancy associated with chronic inflammation. The results suggest that drugs targeted against B lymphocytes or recruitment of innate immune cells toward premalignant tissue may represent a viable strateg...

Molecular steps involved in the creation of gene-silencing microRNAs identified

...V life cycle and with tumor suppression. The study identifies three proteins that work together in the cytoplasm to create finished miRNAs. Individually, each of the proteins was known previously, but their joint role in producing miRNAs is newly delineated here. Equally as important, however, is the fact that ...

Researchers develop new method for facile identification of proteins in bacterial cells

... of flight mass spectrometry (MALDI-TOF MS), which identifies protein fragments based on the time they need to travel a defined distance when being accelerated in a vacuum. In their study, Rolf U. Halden, PhD, PE, assistant professor in the Department of Environmental Health Sciences Bloomberg School of Public...

Researchers seek to discover what really happens when a virus enters the body

...in its attempt to infect other healthy cells, Duca identifies and stains relevant markers from the virus and the host. Under ultraviolet lighting, the chemical stains become fluorescent, allowing Bell and Duca to capture images of the laboratory dish at regular time intervals as the infection progresses. The im...

Aptamer-based Biosensor screens Air Force personnel and equipment

...eness Directorate. "The device is compact, quickly identifies agents, can be used repeatedly and requires very little maintenance to keep it running in the field." The system consists of a spray, developed at the directorate's Brooks City-Base, Texas, facilities, and a hand-held "green box," which determines i...

Scientists show that tick-borne flaviviruses use a novel mechanism to evade host defenses

... failure occurs in the signaling pathway, and then identifies some of the interacting partners in the cell and virus." Prior to this work, Dr. Bloom says, scientists knew only that NS5 helped tick-borne flaviviruses replicate. RML's Sonja Best, Ph.D., who spearheaded the Langat virus work, says the group will ...

Tagging pathogens with synthetic DNA 'barcodes'

...ight is four times that of red light, for example, identifies a "4G1R" probe. The researchers say that up to 1,000 different codes can be created using only three fluorescent dyes. To amplify the signals, the researchers attached many DNA probes to the surface of polystyrene microbeads 5.5 microns (millionths ...

Treatments have same target, different responses for lung cancer patients with genetic mutation

The gene mutation that identifies the lung cancer patients most likely to respond to the drug gefitinib (Iressa) is not associated with a response to the drug cetuximab (Erbitux), according to a new study published in the August 17 issue of the Journal of the National Cancer Institu...

UIC researchers show protein routes messages in nerve cells

...r gets attached. The work by the researchers also identifies the cytoskeleton proteins to which the receptors are tied: actin. "Many researchers have identified proteins that interact with glutamate receptors, but there's never previously been a link found to the cytoskeleton," said Featherstone. "This work f...

Clear rules needed to govern deep sea bioprospecting: UNU

...onals in international waters. The UNU-IAS report identifies shortcomings in UNCLOS, the Convention on Biological Diversity and intellectual property rights instruments governing access and benefit-sharing to genetic resources. These include the need to: * Establish whether describing the sequence of a ge...

A Father’s Day Gift: Free DNA Paternity Testing

...onals in international waters. The UNU-IAS report identifies shortcomings in UNCLOS, the Convention on Biological Diversity and intellectual property rights instruments governing access and benefit-sharing to genetic resources. These include the need to: * Establish whether describing the sequence of a ge...

New understanding of jet lag

... a period of several days. Importantly, the study identifies the neurotransmitter GABA (gamma-aminobutyric acid...," Block said. "Most importantly, the new research identifies the mechanism that couples the two parts of the SCN clock." He suggested that the differing rates o...

Scientists discover genetic pathway responsible for breast cancer cell growth

...nstitut de Recherches Cliniques de Montreal (IRCM) identifies 153 genes that respond to estrogen and one in particular that can be used to halt the growth of breast cancer cells. The study, published in today's Proceedings of the National Academy of Sciences (PNAS), will focus future research for a breast cance...

Eleven gene 'signature' reliably predicts cancer prognosis

...pact on patient care." TITLE: Microarray analysis identifies a death from cancer signature predicting therapy failure in patients with multiple types of cancer ...

Immune system has evolved to prevent autoimmune disease

...nd astronomy. "When we get sick, the immune system identifies the particular antibodies that are effective, as it rapidly creates and mass produces mutant white blood cells called B cells that make only these antibodies." Deem said prior research has identified a number of alternate strategies the immune syste...

UF study first to quantify validity of DNA I.D. tool using marine snails

... a decade may be a hand-held device that instantly identifies any species from a snippet of animal tissue, says a University of Florida researcher. That may be possible thanks to scientific advances that include the first test quantifying the effectiveness of a DNA identification tool among brightly colored sh...

UT Southwestern researchers develop screening test for cells that activate immune system

...te a large-scale, cell-based screening method that identifies which compounds activate immune-response cells that hold promise for future cancer-fighting vaccines. The new screening technique can scan thousands and even millions of compounds to identify those that activate dendritic cells, which are on constan...

Plant genes identified that can form basis for crops better adapted to environmental conditions

...ss or Arabidopsis thaliana. Large-scale research identifies genes involved in capillary root formation First of all, the researchers developed a special method − the Lateral Root-Inducible System (LRIS) − with which they are able to have capillary roots grow in a controlled manner. They studied ...

Researcher uncovers details of how cancer spreads

... an author of the paper. "So from here, if someone identifies a drug that targets this pathway, it is possible the drug will not affect normal cell function but will affect cancer cell activity." That, in turn, would alleviate drug side effects. Guan and his colleagues used a cultured cell line to study cancer...

1 2 3 4 5