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Tag: "identifies" at biology news

Novel technology detects human DNA mutations

...detection specificity and sensitivity. One segment identifies any mutations in the DNA and the probe, a highly sensitive gold nanoparticle, creates a strong signal accurately indicating the presence of a specific target SNP. Proof of principle, reproducibility, and the robust, simple and rapid characteristics o...

Fox Chase Cancer Center scientists identify immune-system mutation

...s them to the killer-cell pathway. "Our new study identifies this defect as a point mutation in the zinc finger transcription factor Th-POK. We show that when the normal form of this factor is active in all developing lymphocytes, it can redirect would-be killer cells to the CD4 helper T cell lineage. This ind...

Drug That 'Tags' Decision-making Areas Of The Brain May Aid

...rug ?Nifrolidine ?is a selective binding agentthat identifies specific areas of the brain responsible fordecision-making, learning and memory. Lead researcher JogeshwarMukherjee, UCI associate professor of psychiatry and human behavior,developed Nifrolidine to measure a subtype of nicotine receptors in thelivin...

A much-needed shot in the arm for HIV vaccine development

...the collaboration of over 140 scientistsworldwide, identifies the major scientific roadblocks facing HIVvaccine development, outlines a strategic approach to addressing them,and proposes an innovative collaborative model that ensures thatresearchers across the globe are harnessing their efforts towards acommon ...

An entropy-based gene selection method for cancer classification using microarray data

...dancy among the genes. Results The present study identifies a subset of features by maximizing the relevance and minimizing the redundancy of the selected genes. A merit called "uncertainty" is employed to measure the relevance and the redundancy of the genes. In order to find a more representative subset of ...

White blood cell waste disposal system plays critical regulatory role

A new research study identifies a critical inhibitory step that is a key component of the feedback circuit regulating the balance between neutrophil production and destruction. The research, published in the March issue of Immunity, suggests that the process for disposal of dying n...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...ylvania School of Medicine has headed a study that identifies another molecular player influencing the initiation of colon cancers. This study will be published in the February 1 issue of the journal Genes and Development. An animal model with an inactivating mutation within the mouse equivalent of the APC ge...

UCSD team discovers specialized, rare heart stem cells in newborns

...urthermore, the developmental lineage marker which identifies undifferentiated cardiogenic precursors suggests the feasibility of isolating isl1+ cardiac progenitors from mouse and human embryonic stem cell systems during cardiogenesis." "We think that these cells normally play an important role in the remodel...

International HapMap consortium expands mapping effort

...tain pattern more often in people with the disease identifies a genomic region that may contain genes contributing to the condition. Because the Phase II HapMap will be so detailed, researchers will be able to use its SNP signposts to zero in on that particular genomic region and search for specific genes invol...

Biodiversity hotspots identify conservation priorities

The new book Hotspots Revisited identifies 34 regions worldwide where 75 percent of the planet's most threatened mammals, birds, and amphibians survive within habitat covering just 2.3 percent of the Earth's surface (roughly equivalent to the combined areas of the five largest U.S. states). T...

McGill researchers shed light on formation of carcinogen in food

...s break down when heated to produce furan. It also identifies other food components, such as vitamin C and polyunsaturated fatty acids, which may produce furan as an unwanted by-product of cooking, bottling or canning food products. "Furan and its derivatives sometimes form when amino acids or sugars are broke...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

... with matching sections of messenger RNA. The cell identifies the resulting messenger RNA strand as faulty and chops it up. As a result, the genetic blueprint isn't delivered and the protein never gets made. "Gene silencing is an example of using "molecular scissors" at its most advanced level," Raoul explains...

White Blood Cell 'Waste Disposal' System Plays Critical Regulatory Role

A new research study identifies a critical inhibitory step that is a key component of the feedback circuit regulating the balance between neutrophil production and destruction. The research, published in the March issue of Immunity, suggests that the process for disposal of dying n...

Bioelectronic ‘signatures?hold key to DNA mutations

...generating an electronic “fingerprint?that rapidly identifies all possible combinations of SNPs. Wang’s results recently were featured as the cover story in the March issue of Analytical Chemistry and were published earlier this winter in the Journal of the American Chemical Society. The article can be found o...

A little stress gives beneficial oomph! to immune system

...ivated by wounding or infection or until the brain identifies a stressful situation. When that happens, the brain releases hormones that set troops of these immune cells into motion. The cells travel to potential battle stations ?primarily the skin along with the lymph nodes that drain the skin. "Most immune c...

Master gene controls healing of skin in fruit flies and mammals

...' study, published April 15 in the journal Science identifies a master gene called grainyhead that activates wound repair genes in the cells surrounding an injury in the cuticle of a fly embryo. These wound repair genes then regenerate the injured patch of cuticle. In a separate study published in the same iss...

Ariadne Genomics Announces the Release of PathwayStudio?Central, Client-Server Software for Biological Pathway Analysis

...udio?Central builds pathways from microarray data, identifies biomarkers, and models drug responses. The software comes with ResNet?database of 500,000+ functional relationships and MedScan?tool for automatic extraction of information from scientific literature. ResNet?database of functional relationships for ...

Future diabetes drugs may target new protein interaction

...n the glucose-making process, but the new research identifies a critical regulatory step the researchers say could be targeted as well. PGC1, which Puigserver isolated and cloned in 1998 as a postdoctoral fellow at Harvard, controls gene expression in the liver and other tissues. In the liver, it triggers the ...

PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information

...n the glucose-making process, but the new research identifies a critical regulatory step the researchers say could be targeted as well. PGC1, which Puigserver isolated and cloned in 1998 as a postdoctoral fellow at Harvard, controls gene expression in the liver and other tissues. In the liver, it triggers the ...

Computational verification of protein-protein interactions by orthologous co-expression

...n the glucose-making process, but the new research identifies a critical regulatory step the researchers say could be targeted as well. PGC1, which Puigserver isolated and cloned in 1998 as a postdoctoral fellow at Harvard, controls gene expression in the liver and other tissues. In the liver, it triggers the ...

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