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Tag: "identified" at biology news

Exploring the dark matter of the genome

...lyze the raw sequence data, in search of genes. We identified patterns of codons that might indicate a gene splice-site or a promoter, for example. We mapped experimentally derived evidence of messenger RNAs back to the matching heterochromatin sequence. And we looked for sequences similar to ones already known...

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents

...ng and lung cancer tissue samples. The researchers identified a very small, rare set of resting cancer stem cells in the lung cancer samples that looked and behaved much like normal adult lung tissue stem cells. Both the cancer and normal stem cells were protected equally by multiple drug resistance transporter...

Potent possibilities for parasite attack

...hree parasite species that cause Leishmaniasis has identified a small number of genes, many new to biology, that will provide a framework to target the search for new treatments. Leishmaniasis is a devastating disease that affects about two million people each year and threatens one-fifth of the world's populat...

Gene responsible for common hearing loss identified for first time

...ng loss among white adults, otosclerosis, has been identified for the first time, a scientist told the annual conference of the European Society of Human Genetics in Nice, France. Ms Melissa Thys, from the Department of Medical Genetics, University of Antwerp, Belgium, said that this finding may be a step towar...

Researchers identify protein pathway involved in Parkinson disease development

...ells that is altered by genetic mutations recently identified in Parkinson disease development. These new findings show how the mutations affect cellular function and could provide a target for drug therapies to treat the disease. The research by a team of Emory University scientists will be published June 18...

Electric fish conduct electric duets in aquatic courtship

...ecies rarely breeds successfully in captivity) and identified nine common motor displays and 11 specific pulse sequences common to courtship and mating. "Knowing the electrical and motor patterns during courtship allows for further exploration of such topics as mate choice and neural basis of pattern generat...

Researchers develop buckyballs to fight allergy

A research team has identified a new biological function for a soccer ball-shaped nanoparticle called a buckyball – the ability to block allergic response, setting the stage for the development of new therapies for allergy. Allergic disease is the sixth leading cause of chronic d...

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state

... express. Now, a team of Canadian scientists has identified 1,155 genes under the control of a gene called Oct4 considered to be the master regulator of the stem cell state. A comprehensive molecular definition of stem cells is emerging: according to this research, stem cells are cells that keep their DNA pac...

Revealed -- Mosquito genes that could be controlling the spread of killer viruses

...ransmits deadly viral diseases to humans have been identified in new research out today in Science. The immune ... published in this week’s Science. The researchers identified over 350 genes which are involved in the Aedes mosquito’s immune system, and discovered that they ev...

How plague-causing bacteria disarm host defense

...lifornia, San Diego (UCSD) School of Medicine have identified a novel molecular target for an effector protein called YpkA, one of several effectors of the bacteria Yersinia – the pathogen responsible for the Middle Ages' "Black Death" and a virulent form of food poisoning today. Their study will be published ...

Skimmed milk -- Straight from the cow

...adable straight from the fridge. They have already identified a cow, Marge, with the genes required to do this and say a commercial herd is likely by 2011. The milk is very low in saturated fats and so should be high in polyunsaturates and monounsaturated fats. Experts say that the discovery of these rogue m...

First confirmed common genetic risk factors for breast cancer

...unction normally. Previous investigations have identified about a dozen genetic mutations associated with br.... However, BRCA-1, BRCA-2 and the other previously identified breast cancer susceptibility genes are mutated in a relatively small percentage of women. "Risk m...

Extra-aggressive form of idiopathic pulmonary fibrosis identified

...ther molecular studies in a subset of patients and identified a number of genes that were differentially expressed in both groups, suggesting that rapid progressors are biologically distinct from slow progressors. "While preliminary, these results may allow investigators to identify biomarkers of disease pr...

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

...26 rapid progressors and 88 slow progressors. They identified 437 differentially expressed genes between the groups. Specifically, lungs of rapid progressors, who were predominantly males who smoked, overexpressed genes involved in the development of tissues and organs (morphogenesis), oxidative stress, cell mi...

Detecting cold, feeling pain: Study reveals why menthol feels fresh

Scientists have identified the receptor in cells of the peripheral nervous sy...ceptor on sensory neurons. Most recently, they identified the receptor of isothiocyanate compounds, which constitute the pungent ingredients in such plants as...

Early exposure to indoor fungus molecules may protect infants against future allergies

...Allergy and Air Pollution Study (CCAAPS), who were identified as being at greater risk for future allergies because at least one parent had known allergies. The CCAAPS, funded by the National Institute of Environmental Health Sciences, is a five-year study at UC examining the effects of environmental particu...

Salk scientists hammer out a pathway that promotes muscle cell survival in mice

... at the Salk Institute for Biological Studies have identified an enzyme that pumps up a cell’s ability to maintain healthy muscle and restores normal muscle function in genetically engineered mice with weak muscles. The study, published online in Nature Medicine, is the first to explore the part this enzyme pla...

'Insulator' helps silence genes in dormant herpes virus

...ene for months or even years. The researchers have identified an "insulator" ?a stretch of DNA about 800 base pa...irology, mark the first time an insulator has been identified in a virus and may lead to ways to develop strategies to manipulate the virus. Insulators, also ...

Scientists discover rare 'gene-for-gene' interaction that helps bacteria kill their host

...a single gene in an animal or human host have been identified so far. Photorhabdus is a family of bacteria th...ct itself against this particular defence. They identified the inhibitor as a small molecule called 1,3-dihydroxy-2-(isopropyl)-5-(2-phenylethenyl)benzene, kno...

Master regulatory gene of epithelial stem cells identified

...tem cells, while other master regulators have been identified for blood stem cells and spermatocyte stem cells, suggests a fundamental requirement for tissue specificity of these regulators that we don’t understand," says McKeon. "Dissecting the genetic programs controlled by these regulators will tell us much ...

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