Team Invents Device For Weighing Individual Molecules
...This technology may lead to new forms of molecular identification that are cheaper and faster than existing methods, as well as revolutionary new instruments for proteomics. According to Michael Roukes, professor of physics, applied physics, and bioengineering at Caltech and the founding director of Caltech's Kavl...Massey Cancer Center researcher helps to identify a piece of the cancer puzzle
...role in supplying nutrients to solid tumors. This identification may help researchers gain a greater understanding of the cell signaling that occurs when cancer cells try to co-opt nearby healthy cells into helping to feed and spread growing tumors. The structure of the protein, Ang2, will be published this week ...Whole genome promoter mapping - Human Genome Project v2.0?
...s are regulated or even related to each other. The identification of such a large number of promoters means that we can begin to answer these sorts of questions." ...NYU, Rockefeller researchers find complexity of regulation by microRNA genes
...h team developed "PicTar," a new algorithm for the identification of microRNA target sites in the genome and used it to compare sequences from eight different vertebrates. "The study demonstrates that computational methods, in conjunction with the exploding amounts of available sequence data from different species...Scientists identify genes responsible for 'black rot' disease in vegetables
...dy published today, the investigators describe the identification of 75 different genes responsible for Xcc virulence. These genes appear to belong to 13 different functional categories or related metabolic pathways. The researchers hope that the molecular characterization of these pathogenicity-related genes will ...Scientists analyze chromosomes 2 and 4
...s of the effort to analyze the human genome is the identification of all genes, which are generally defined as stretches of DNA that code for particular proteins. The new analysis confirmed the existence of 1,346 protein-coding genes on chromosome 2 and 796 protein-coding genes on chromosome 4. As part of their ex...Analysis Of Human Genome To Predict The Development Of Illnesses
...t, drawn up by Navarre University, will enable the identification of therapeutic targets for cancer, depression and ...fferent treatments administered, thus enabling the identification of new, more effective therapeutic targets. This new tool is available on Internet, thus enabling a...NHGRI targets 12 more organisms for genome sequencing
...ow primate, the marmoset (Callithrix jacchus); and identification of genetic variations (in the form of single nucleotide polymorphisms) in eight strains of rats. The marmoset is a key model organism used in neurobiological studies of multiple sclerosis, Parkinson's disease and Huntington's disease. The marmoset i...Product improves peptide identification for proteomics research
...models in proteomics applications, such as protein identification and biomarker discovery, potentially leading to a .../MS technology will set a new standard for protein identification and analytical performance," said Ken Imatani, product marketing manager for Agilent's ion trap mass...Study reveals candidate targets for anti-retroviral therapeutics
...sistance in isolates of the AIDS virus, HIV, makes identification of new antiviral targets an urgent necessity. Host genes required to support the replication of HIV are a potential source of such novel targets, but relatively few appropriate target genes have been identified in animal cells thus far. A new study, ...Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.
...diterranean area. The results obtained allowed the identification of factors that are important in determining the fate of vibrios within the bivalve host, such as bacterial surface ligands, soluble hemolymph components and the ability of bacteria to affect distinct signaling pathways responsible for the hemocyte i...What's really making you sick? Plant pathologists offer the science behind Sick Building Syndrome
Science-based identification of mold and other causes of Sick Building Syndrome may improve its management, say plant pathologists with The American Phytopathological Society (APS). Sick Building Syndrome (SBS) refers to a situation in which building occupants experience health...Bioelectronic ‘signatures?hold key to DNA mutations
...le, electronic devices for the rapid screening and identification of genes that harbor disease. Joseph Wang, direct...r an accurate, ultra-sensitive, rapid and low-cost identification of these SNP variants. “The novelty of the approach is the combination of the nanocrystal tagging o...Discovery may lead to better Candidiasis drug
...es into, and out of, the cell. "This is the first identification of a specific target for histatin," she said. "The finding paves the way for eventually developing a better therapeutic drug for candidiasis." Results of the research were presented today (March 11, 2005) at the International Association on Dental R......ee decades of intensive cancer research led to the identification of a family of receptors, known as HER, that sit antenna-like on the outside of the cell wall and are implicated in certain types of cancer. A team of researchers under Prof. Yosef Yarden, Dean of the Weizmann Institute's Feinberg Graduate School and...Researchers report new pro-inflammatory role for anti-inflammatory enzyme
...ing the mortality associated with the disease. The identification of a pro-inflammatory role for eNOS-derived NO may provide the stimulus for further research in this area and thereby identify novel targets for treatment of inflammatory diseases." ...Disease diagnosis, biodefense among UH chemical research projects
...ing cause of death in the United States. Microbial identification also is important in food safety and biodefense. Traditional culturing and growth-testing methods are being replaced by molecular biology-based methods as genome sequencing advances. This work presents novel DNA-sequence-based methods of sensitive, b...New insight into regulation of blood stem cells
...o provide important in vitro model systems for the identification of genes and compounds that can be used to regulate the process of stem cell differentiation." ...HIV-1 spread through six transmission lines in the UK
...nodeficiency virus type 1 or HIV-1 since the first identification of A ID S in 1982. Despite a recent increase in heterosexually acquired infections within the UK , predominantly originating in sub- S aharan A frica , one of the most prevalent clades (subtypes) of virus within the country remains subtype B, which i......llpox. These findings reveal a new approach to the identification and development of antiviral compounds. This is especially critical at a time when the threat of smallpox as a biological weapon is high. ...