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Tag: "identification" at biology news

Free radical cell death switch identified

...disease, neurodegenerative diseases, and diabetes, identification of the MST-FOXO switch mechanism could provide potential new targets for the diagnosis and treatment of many common age-associated diseases. ...

What controls stickiness of 'smart' chromosomal glue

...on the Rec8 subunit that Polo phosphorylates. Firm identification of such sites will enable more precise studies of the mechanism of function of Rec8, and will also enable scientists to identify other protein targets of Polo kinase, she said. Amon emphasized that the discovery of the importance of phosphorylation...

Origen publishes in Nature a robust and versatile method for creating transgenic chickens

...ed cell killing properties, the time from antibody identification to production in eggs is a matter of months, the purification of proteins from eggs is relatively simple, and good manufacturing practices have long been established for vaccine production in chicken eggs. Moreover, the overall cost of facility and o...

Potato blight pathogenicity explained by genome plasticity

...ns strains. The outcome of their efforts was the identification of single gene, called pi3.4 , that was present as a single, full-length copy in both the virulent and avirulent strains. They also identified multiple copies of pi3.4 only in the avirulent strain ?but, interestingly, these copies represented onl...

Quick -- what’s that smell?

...s longer to smell an odor results in more accurate identification of that odor. This seemingly simple observation ha...erent receptors and that an olfactory code enables identification of specific odorants by the brain. Previous experience and motivational state also interact with odo...

Scientists tie several cancers to common 'oncogene engine'

...ug currently exists to directly suppress MITF, the identification of MITF's role opens a door to potential therapies because the researchers have identified some of the genes and proteins that MITF regulates that new drugs could be used to block. One of the targets is Bcl-2, which enables cancer cells to survive wh...

Prevention is the best option: fighting autoimmune diseases

...dy," says Assoc Prof Fazekas. The highly accurate identification and isolation of regulatory T cells was made possible using sophisticated flow cytometry equipment at the Centenary Institute. The machines use laser beams and advanced optics and electronics toanalyse and purify many kinds of cells at a rate of ove...

Gene therapy injected into the brains' of mice with Huntington's disease

...from HD. Unlike other neurodegenerative disorders, identification of the genetic markers provides a unique opportunity to intercede therapeutically before or extremely early in the disease process–only a small fraction of potential carriers get tested. But, if there was a treatment, especially one that altered the ...

Scientists solve sour taste proteins

...ssor of molecular genetics and microbiology. The identification of these proteins, called PKD1L3 and PKD2L1, could lead to ways to manipulate the perception of taste in order to fool the mouth that something sour, such as some children's medicines or health foods, tastes sweet, he said. The team's findings appea...

Airborne mold spores increase kids' risk for multiple allergies

...visible mold or total mold concentrations, not the identification of specific airborne fungal spores. The UC-led study showed that exposure to specific airborne fungal spores may increase allergic reactions and others could help reduce them. These findings reinforce the idea that not all fungi are created equal, ...

New study reveals signaling pathways required for expansion of pancreas stem cells

...y shown in animal models developed in her lab, the identification of the proteins (BMPs) described in this research is an important step for the potential application of therapies aimed at increasing a pool of cells that will become insulin-producing." ...

A new look at the state of the oceans

...nisms, e.g. taxonomic descriptions, facilitate the identification of species. The data base was re-installed recently and, at present, holds more than 3000 images and over 500 species descriptions. Free access to the data base enables all registered users to add their own images and data, and to supplement existing...

Encoded metallic nanowires reveal bioweapons

...sitive, and unambiguous, yet also fast and simple, identification of the pathogen; preferably, this test should be carried out on the spot, not in a laboratory. Portable miniature biodetection systems that can detect multiple pathogens simultaneously would be ideal for this task. American researchers from Lawrence...

Molecular DNA switch found to be the same for all life

...now available on-line), the researchers report the identification of a helical substructure within a superfamily of proteins, called AAA+, as the molecular "initiator" of DNA replication in a bacteria, Escherichia coli (E. coli), and in a eukaryote, Drosophila melanogaster, the fruit fly. Taken with earlier resea...

Breast stem cells have features similar to 'basal' tumors

...ind of research could in the long-term lead to the identification of new therapeutic targets against breast cancer, particularly the basal subtype." Currently drugs such as Tamoxifen, the aromatase inhibitors or Herceptin are ineffective against basal tumours and chemotherapy is the only option. Dr Lindeman, who ...

Deep-water discovery

...ns of thousands of marine organism samples and the identification of a number of promising potential drugs now in various stages of development for treating cancer, Alzheimer's disease, malaria, AIDS, and other ailments. ...

Drug discovery team to explore newly discovered deep-sea reefs

...ns of thousands of marine organism samples and the identification of a number of promising potential drugs now in various stages of development for treating cancer, Alzheimer's, malaria, AIDS and other ailments. ...

Viral genetic differences are possible key to HIV dementia

...he viral envelope gene known as the V3 loop. "The identification of these signature mutations presents convincing evidence that HIV adapts to the local environment within the central nervous system and, moreover, that commonalities in this environment exist across individuals," he asserts. Another mutation in th...

Technique speeds up detecting, treating wound bacteria

... that we get quantitative information and accurate identification on the organisms in five hours or so, whereas the current procedure--culturing and identifying organisms by biochemical activity, etc.--can take one to several days and sometimes weeks, depending on the organism," he said. His technique is also use...

Mayo Clinic study finds two genes predict outcome for breast cancer patients

... of women with early stage breast cancer may allow identification of women who are and are not at risk for early relapse or cancer-related death. Results of the study are published in the April 1 issue of Clinical Cancer Research. "The HOXB13 and IL17BR gene profile was previously discovered as a potential marker...

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