Environmental chemical cocktail may sabotage sperm
...ions for human fertility for two reasons. Firstly, humans are likely to be exposed to more than one such compound at any given time and, secondly, our results show that human sperm are even more sensitive to these compounds than mouse sperm." Prof Fraser and her team tested combinations of three chemicals:...Decisions, decisions: Male or female?
... Van Doren said the same conduit also is active in humans and mice. When communication via the JAK/STAT pathway misfires, diseases such as cancer can result, he said. "Evolutionarily, germ cells are one of the most ancient cell types, needed by every type of animal to reproduce," Van Doren said. "Their dev...A virus-like hitchhiker may trigger bacterial meningitis
...ed strains of bacteria that had been isolated from humans and found that the strains that carried this virus-like stowaway were more likely to have caused disease. How this bacteriophage causes N. meningitidis to become more dangerous is unknown. It may help the bacteria get into the bloodstream, suggests T...Fluorescing lab worms signal longer life spans
...oratory. Most scientists believe the life span of humans and other living creatures is determined by a comb... environmental and chance factors. Twin studies in humans have suggested that genes are only about 15 percent to 30 percent responsible for a person's age at ...Novel plague virulence factor identified
...of mammals. There are different forms of plague in humans -- bubonic, pneumonic and septicemic -- depending on site of infection; and infections in humans are highly lethal if not immediately treated. "Dr Aballay has developed a new model for dissecting ...New Look at DNA Hints at Origin of UV Damage
...of mammals. There are different forms of plague in humans -- bubonic, pneumonic and septicemic -- depending on site of infection; and infections in humans are highly lethal if not immediately treated. "Dr Aballay has developed a new model for dissecting ...Assessing the Amazon River's sensitivity to deforestation
...stimates of future deforestation to understand how humans may be affecting the Amazon. Coe says, "This research will provide us with a better understanding of how sensitive the Amazon river is to human activities and can provide government managers and civil society with a tool for analyzing the costs and b...Can our genes tell the story of our divergence?
Since humans and chimpanzees forged separate evolutionary paths...ill, and their colleagues compared 13,731 genes in humans to their equivalents in chimps to find positively selected genes in both species. Nielsen et al. id...Neandertal femur suggests competition with hyenas and a shift in landscape use
...leolithic archeological period, just before modern humans arrived in Europe. The research will be published...ted with the transition from Neandertals to modern humans was that people became more mobile and their territories became much larger. They became less locall...New protein vital for immune response is found in surprise location
...edical Institute. "Viruses have evolved along with humans and have developed strategies to evade the host's immunity. It's quite possible that some viruses may target MAVS in order to achieve successful infection. In those cases, therapies that enhance MAVS expression or activity may be a viable option for ...... the toadfish brain are less tangled than those in humans and other creatures that must cram their nerves through relatively small openings in the skull. The human vestibular (balance) system relies on fluid-filled ear canals that tell us which end is up. The toadfish vestibular system is similar enough to...Why are coyotes getting more aggressive?
...last stage before coyotes actually start attacking humans -- such as small children that are perceived by th... in the past two decades, several dozen attacks on humans have been reported in California. Coyotes, which are closely related to dogs and wolves, are ubiqui...Pinpointing the cause of a neurodegenerative disorder
...GFi-1 showed Purkinje cell degeneration, just like humans with SCA1. "The overall picture we have now is that glutamine expansion causes some aspects of the pathology of SCA1 in part by enhancing the activity of the domain that is outside the glutamine repeat," said Zoghbi. The finding offers insight into...'Punctuated' evolution in the human genome
... is the primary cytogenetic distinction separating humans and their evolutionary progenitors. Within this 7...nds to the time period following the divergence of humans and Old World monkeys, but before the divergence of humans and great apes. For the past 10 million y...Pinpointing a culprit molecule in Alzheimer's disease
...ave the abnormal protein underlying the disease in humans show little pathology of the disease. Specifically, such mice are genetically altered to overproduce mutant human amyloid precursor protein (APP). It is this protein that, when clipped by enzymes, produces the amyloid beta (Ab) peptide that clusters ...Scientists focus on 'dwarf eye'
...team successfully mapped the MFRP gene mutation in humans and discovered that the protein was completely missing from nanophthalmos patients. In a normal human eye, the MFRP protein is located on the surface of the retinal pigment epithelium (RPE), which is located beneath the retina and helps maintain pho...Woods Hole Research Center plans controlled burn in Amazon rainforest
... it even more vulnerable to subsequent fires. When humans move into an area and begin clearing forest, they seldom abandon it and move away, so until education can alter their behavior, repeated sources of ignition in the future are all but guaranteed. The expectation is that the second fire will be hotter ...Looks matter to female barn swallows
...dynamic and continual. This is something that most humans can relate to -- think of how much time and money we spend on our looks and status long after we have established stable relationships." Barn swallow ( Hirundo rustica erythrogaster ) males have a wash of reddish-chestnut color from their throats t...'Jumping genes' contribute to the uniqueness of individual brains
... by mutations rendering them dysfunctional, but in humans a hundred or so are free to move via a "copy and paste" mechanism. Long dismissed as useless gibberish or "junk" DNA, the transposable L1 elements were thought to be intracellular parasites or leftovers from our distant evolutionary past. It has bee...Researchers devise new technique for creating human stem cells
...ramming process using eggs, because in the case of humans it is very difficult to obtain eggs in any quantity and difficult or impossible to genetically manipulate them," he said. "But embryonic stem cells can be grown in large quantities. We can isolate the components of the reprogramming machinery, and we...