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Tag: "humans" at biology news

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

... of damage to our DNA, but under normal conditions humans andother mammals are capable of removing UV-induced DNA damage by a DNArepair mechanism called nucleotide excision repair. Insufficient repairof UV-induced DNA damage, which for example may occur after excessiveunprotected sunbathing, can lead to cel...

W.M. Keck Foundation funds study of friendly microbes

...ial (symbiotic) relationships between microbes and humans will allow light to be shed on this previously mysterious interior world. Our objective is to understand how the human body functions as a carefully woven fabric of interacting species. Ultimately, such understanding promises to provide new ways of f...

Neuronal 'traffic jam' marks early Alzheimer's disease

...also examined brain sections taken at autopsy from humans with different stages of Alzheimer's disease. They...nhance the pathology they observed in the mice and humans by reducing the levels of a key transport protein, kinesin-1, the cell's principal molecular motor f...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...paper.Previously, the Varki lab found in 1998 that humans are uniquelydifferent from other mammals studied i...In a 2003 study**, the UCSD researchers found that humans havenaturally occurring antibodies that are directed against Neu5Gc. In thecurrent Nature Medicine p...

Research advances quest for HIV-1 vaccine

...tion has been a successful strategy for protecting humans from many potentially harmful viruses. However, designing a suitable vaccine for HIV-1 has been a highly challenging and thus far unsuccessful endeavor. HIV-1 is enormously variable and it has been difficult to isolate antibodies that will recognize ...

Study Links Ebola Outbreaks To Animal Carcasses

All recent Ebola virus outbreaks in humans in forests between Gabon and the Republic of Congo...ndangered apes from illegal hunting and to protect humans from deadly outbreaks." The paper provides definitive proof for the assumption that Ebola moves fro...

Bacteria collection sheds light on urinary tract infections

...rs in animals. E.coli is common bacteria found in humans and animals. Thousands of E.coli live in the organs of humans and animals and provide multiple benefits such as aiding in digestion of certain nutrients. However,...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...tuberculosis, is responsible for more morbidity in humans than any other bacteria. The emergence of multi-drug resistant strains of M. tuberculosis has prompted the search for new drug targets and a better understanding of the mechanism of resistance in this bacterium. Several spans of DNA in the M. tuberc...

Found: Missing sequence of the human Y chromosome

...c determinant ofsex-related stature differences in humans and is in close proximity tothe Y centromere. In addition, the GBY, or gonadoblastoma locus, whichis responsible for development of tumors associated with theundifferentiated gonad, has been genetically mapped to the region.Because the "missing" sequ...

Molecular machine may lead to new drugs to combat human diseases

...ay play specialized roles in cell behavior. While humans have introns, they don't have Group I introns. Many pathogens that cause human diseases, however, do have Group I introns, including the HIV opportunistic infections pneumocystis, a form of pneumonia, and thrush, an infection of tissues in the oral c...

Sea skate experiment sheds light on human cell transport

...wledge to other cells and other animals ?including humans ?is what makes the findings exciting." In type 1 diabetes, cells lose their ability to transport glucose. Goldstein and Musch say their findings could explain the problem. People with type 1 diabetes don't produce insulin. Without that hormone, vesi...

Yale Scientists Find MicroRNA Regulates Ras Cancer Gene

...matics and found the relationship to Ras. Let-7 in humans is identical to the sequence in the worm, and both binding site and pathway for Ras are highly conserved. Tissue from lung cancer tumors, compared with their normal adjacent tissue, had reduced let-7 and increased Ras -- the brakes on Ras were remov...

Mouse brain tumors mimic those in human genetic disorder

... developed a mousemodel in which the animals, like humans with the disease, have oneabnormal copy of the gen...after a few monthsin mice and after a few years in humans tells us there may be growthsignals that are produced early in life, which are critical for tumorfor...

New Clues Add 40,000 Years to Age of Human Species

...e earliest remains of pre-human ancestors. Modern humans were not a priority at the time, and when members ...frican continent, but they differed on when modern humans first evolved, how humans dispersed to populate the globe, and what happened when, or if, modern hum...

Spider Venom Could Yield Eco-Friendly Insecticides

...ge Australian spider with a bite that is deadly to humans and insects -- is an ideal source of venom for King's research. The spider "cooperates" by rearing up in a fighting stance when provoked, making it relatively easy for researchers to aspirate venom directly from its fangs. Since Australian funnel-web...

Enzyme shown to help protect genomic stability

...es known as telomeres, has been linked to aging in humans and an elevated risk for aging-related diseases, the most prominent of which is cancer. For this reason, insights into the mechanisms of gene silencing could provide important guideposts for new approaches to retarding aging or treating cancer. Now,...

Researchers identify target for cancer drugs

...mplex conserved in species as diverse as flies and humans supports the claim that the mTOR/rictor complex is indeed a missing piece of the puzzle. According to Sarbassov, "If we find a molecule that can block the mTOR/rictor complex, then we may be able to prevent Akt from becoming active and contributing ...

Experiments provide proof of how traveling in groups protects insects

...ay. Why such groups of insects form has mystified humans for thousands of years. One firmly held belief was that God was punishing men and women for their sins. A more recent, scientific theory has been the "safety-in-numbers" idea -- that the small animals congregate periodically as a way of protecting th...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

...y genes are packaged in yeast. To go from yeast to humans required a technological breakthrough, however. "...t have such clusters, but HOX clusters in mice and humans boast relatively huge sections of chromatin completely covered with tags. This was not seen before b...

Experiments provide proof of how traveling in groups protects insects

...ay. Why such groups of insects form has mystified humans for thousands of years. One firmly held belief was that God was punishing men and women for their sins. A more recent, scientific theory has been the "safety-in-numbers" idea -- that the small animals congregate periodically as a way of protecting th...

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