Targeted virus compels cancer cells to eat themselves
...cellular self-cannibalization. The result was a huge difference in tumor volume among mice with subcutaneous malignant glioma that got hTERT-Ad and those that received a different, non-replicating virus. Average tumor size in the hTERT-Ad group was 39 cubic millimeters, while those receiving the other ...Cougar predation key to ecosystem health
...re virtually absent, mostly just scared off by the huge influx of human visitors. With their natural enemy gone, growing and ravenous deer populations ate young cottonwood trees almost as quickly as they sprouted, robbing streambanks of shade and erosion protection. As a result, floodplains began to ero...Better sludge through metagenomics
...al improvement in the process would translate into huge savings and spell relief for environmental engineers. David Jenkins is Professor Emeritus of Environmental Engineering at the University of California at Berkeley. His research spans some forty years of international professional practice in water...Far more than a meteor killed dinos
...m's greenhouse warming effect and finally a second huge impact that finished them off. So where's the crater? "I wish I knew," said Keller. "There is some evidence that it may have hit in India, where a crater of about 500 kilometers in diameter is estimated and named Shiva by paleontologist Sankar Cha...'Fruit fly dating game' provides clues to our reproductive prowess
...m's greenhouse warming effect and finally a second huge impact that finished them off. So where's the crater? "I wish I knew," said Keller. "There is some evidence that it may have hit in India, where a crater of about 500 kilometers in diameter is estimated and named Shiva by paleontologist Sankar Cha...Researchers find docking sites for glucocorticoid receptor and Hsp90
...y effective, and glucocorticoids have been used in huge amounts in the last 40 years. Unfortunately, they are associated with very severe side effects. " Side effects include osteoporosis, cataracts, ulcers, hypertension, impaired wound healing, diabetes and depression. Thus narrowing the point of atta...... the humble wood ant navigates over proportionally huge distances, using just very poor eyesight and confusing and changing natural landmarks. The research could have significant benefits in the development of autonomous robots and in furthering our understanding of basic animal learning processes. Scie...Researchers barcode DNA of Venice museum's vast fungi collection
...iences, Letters and Arts. "We are building up a huge molecular database that will be available to the entire scientific community," said Matteo Garbelotto, UC Berkeley adjunct associate professor of ecosystem sciences and principal investigator of the project. "In addition to aiding research on the pro...First-time analysis reveals millions of Europeans left at risk from influenza
...nalysis from this month's Vaccine 1 highlights the huge gap between current vaccination coverage across Europe and the recommendations endorsed by the European Union. Currently, only one third (35%) of all high risk populations are receiving seasonal influenza vaccine in Europe, resulting in avoidable mor...MIT designs portable 'lab on a chip'
...ed the effectiveness of the design. "It's just a huge improvement with a very simple idea," said Bazant. Thorsen's group is working toward integrating the pumps into a portable blood analysis device, which soldiers could carry onto the battlefield. If exposure to chemical or biological weapons were su...New engineered drug may offer prolonged arthritis relief
...week to perhaps twice a month, and that would be a huge clinical gain," she said. By remaining at the site of disease, the drug also might cause fewer negative side effects than the unmodified drug, the researchers added. The team reported an initial proof-of-concept study on Saturday, Oct. 14, at the...Shrinking ponds signal warmer, dryer Alaska
...g of the water table that could have a potentially huge impact on waterfowl production," said Dave Verbyla, co-author and professor in the School of Natural Resources and Agricultural Sciences at UAF. "This is an issue relevant to flyway management in terms of all the waterfowl that might use the Yukon...Distinguishing friend from foe in the battle against cancer
...Molecular and Cell Biology Laboratory. "We've made huge progress identifying specific events that change normal proteins into proteins that cause cancer and developing drugs that target those proteins. This work provides another potential direct target for development of cancer drugs." The Hunter lab pr...Giant insects might reign if only there was more oxygen in the air
...period, about 300 million years ago, was a time of huge and abundant plant life and rather large insects -- dragonflies had two-and-a-half-foot wing spans, for example. The air's oxygen content was 35% during this period, compared to the 21% we breathe now, Kaiser said. Researchers have speculated that th...End of deforestation in view? Experts advance new way to size up global forest resources
...vel depends largely on Brazil and Indonesia, where huge areas of tropical forests are rapidly being cut and cleared. Encouragingly, in many other tropical areas forests are re-growing. Studies in Central America show tree cover in El Salvador grew by about one-fifth from 1992 to 2001. Forests are also ...Finding an answer to Darwin's Dilemma
...monly known as "Darwin’s Dilemma" ?may be due to a huge increase of oxygen in the world’s oceans, says Que...Science Express, Dr. Narbonne’s team argues that a huge increase in oxygen following the Gaskiers Glaciation 580 million years ago corresponds with the firs...Ebola-outbreak kills 5000 gorillas
...ly extinct from these areas but it has pushed once huge populations down to smaller sizes at which they are dramatically less resilient to illegal hunting and other looming threats. Just as troubling are recent studies showing that the Ebola infection wave is spreading rapidly towards several of the re...Train your brain to hear your friends at a party
...ld barely hear what they were saying and it took a huge effort of concentration to follow any conversation. During the week, I gave up and spent a lot of time at home on my own because it was so distressing and tiring to be with lots of people or in a noisy place." Our ability to detect a particular so...Researchers link ocean organisms with increased cloud cover and potential climate change
...ea by about 15 watts per square meter. "This is a huge signal," said Nenes. "You would normally expect to see a change of a couple of watts." The Southern Ocean is ideal for study because it is largely untouched by pollution and has relatively steady temperature and meteorological conditions during t...'Protecting virus' offers instant flu protection and converts flu infections into their own vaccines
...ofessor Dimmock's protecting influenza virus has a huge but specific deletion of around 80% of the RNA of one of these 8 strands. This deletion makes the virus harmless and prevents it from reproducing by itself within a cell, so that it cannot spread like a normal influenza virus. However, if it is ...