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Tag: "host" at biology news

Statins stop hepatitis C virus from replicating

...ted to cytotoxicity, meaning they did not kill the host cell. Additional experiments also suggested that, "the statins possess the ability to inhibit the replication of HCV RNA via a specific antiviral mechanism," the authors report. The researchers tested the theory that certain proteins are required fo...

In drug design, a loose fit may be best bet

...nge the way that drug therapies are designed for a host of health problems, from smell and taste disorders to heart disease, asthma, migraine, and pain. The study is published in the May 12, 2006, issue of the "Journal of Biological Chemistry". The researchers looked at thyrotropin-releasing hormone, or ...

Infected for life

...ism that latent viruses use to remain alive in the host cell," suggests Fraser. Present treatments of HSV-1 rely on acyclovir-based drugs that target the viral polymerase and inhibit viral DNA replication during the acute infection. However, they do not target the latent infection, and thus cold sores ...

Researcher gives hard thoughts on soft inheritance

...ion, higher organisms from plants to humans have a host of developmental problems, from dwarfing in plants to certain death in mice. The next level of gene regulation studied in epigenetics is DNA packaging. DNA is wrapped around proteins similar to the way that thread is wrapped around a spool. Loosely...

Plants tell caterpillars when it's safe to forage

... separated the effects of photoperiod from that of host plant volatiles to tease out their relative contri...tial victims, caterpillars use variations in their host plant's volatile production to reduce the risk of unpleasant encounters with wasps. Now that they've...

Butterfly farming to help save rain forest

...ersity survey of the butterfly community and their host plants within the Iwokrama International Centre for Rain Forest Conservation and Development Reserve. The survey will work with the indigenous Amerindian communities within the reserve and the surrounding North Rupununi District with the ultimate aim...

Pathway toward gene silencing described in plants

...ion, higher organisms from plants to humans have a host of developmental problems, from dwarfing in plants to certain tumors in humans, and death in mice. One role of DNA methylation is to turn off repetitive genes, such as transposable elements that can move or spread throughout a genome and disrupt othe...

Researchers find 'secret weapon' used by SARS virus

...m DNA to make interferon beta, which is crucial to host immunity," said UTMB professor of microbiology and...for SARS." Although many viruses interfere with host cells making messenger RNA or translating it into infection-fighting proteins, only one other virus ...

HIV-1's high virulence might be an accident of evolution

...high efficiency, also has a protective role in the host immune system. The viral Nef protein ratchets down...tain viral persistence in the context of an intact host immune system," the researchers said. "The findings suggest that the gene function was lost during v...

UGA researchers find that hunting can increase the severity of wildlife disease epidemics

...hani said. "If we want to control a disease in the host population, the timing of the hunting season can be chosen to be optimal for that." ...

Finding paves way for better treatment of autoimmune disease

... also resolved symptoms in a model of graft versus host disease, a problem for some bone marrow transplant patients when immune cells from the donor start attacking. This finding indicates a potential role for helping transplant patients keep new organs, the researchers say. Dr. Iwashima has an Alcoholi...

Wild vs. lab rodent comparison supports hygiene hypothesis

...not been as challenged during everyday life by the host of microbes commonly found in the environment. The study suggests that an overly hygienic environment could simultaneously increase the tendency to have allergic reactions and the tendency to acquire autoimmune disease, despite the fact that these ...

Researchers show how brain decodes complex smells

...Instead, these nerve cells, or neurons, detect the host of chemical compounds that comprise a rose's perfume. Smarter sections of the brain's olfactory system then categorize and combine these compounds into a recognizable scent. According to the researchers, it's as if the brain has to listen to each mus...

With few factors, adult cells take on character of embryonic stem cells

...uman embryonic stem cells might be used to treat a host of diseases, such as Parkinson's disease, spinal cord injury, and diabetes," said Shinya Yamanaka of Kyoto University in Japan. "However, there are ethical difficulties regarding the use of human embryos, as well as the problem of tissue rejection fo...

Successful transplantation from pig embryos to mice

...insulin their bodies fail to produce, as well as a host of risks that includes blindness, amputation, kidn...ndow, however, they may be too well-developed: The host identifies these cells as foreign, causing the body to reject them. By transplanting tissues from pi...

Even a little cooling helps after cardiac arrest

... a snail and ends in a bird, with the intermediate host animals being primary variables among worm species...matode species." If any one requisite intermediate host is missing, the parasite cannot reproduce and hence will be underrepresented in the resident snail p...

How healthy is that marsh? Biologists count parasites

... a snail and ends in a bird, with the intermediate host animals being primary variables among worm species...matode species." If any one requisite intermediate host is missing, the parasite cannot reproduce and hence will be underrepresented in the resident snail p...

Cornell researchers find serious fish virus in Northeast for first time

...ational agency usually imposes restrictions on any host country with VHSV to prevent fish from being moved... public, this specific virus does not appear to be host specific to the species it infects," Bowser said. The virus is known to infect round gobies, muskell...

When the going gets tough, slime molds start synthesizing

...over millions of years to provide new ways for the host organisms to survive and prosper. Understanding the diversity of natural chemicals and the machinery that produces them gives us a window to look back in time and understand how organisms evolve at the molecular level." ...

For diseases, when it comes to sharing a home, only close relatives will do

... and found that strains are more likely to share a host if they are more closely related. In this way "p... occurs within the hosts," adds Koskella. To win host resources away from a non-relative, theory assumes the pathogens will increase exploitation of the h...

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