Macrophage signaling may affect hormone resistance in prostate tumors
... eventually progress to an antagonist-resistant or hormone independent form of cancer, according to David W. ...n the prostate tumor microenvironment might affect hormone resistance.Using cell biology methods, they discovered a mechanistic explanation for at least one fo...New study reveals promising osteoporosis treatment
...rosis treatments, such as bisphosphonate drugs and hormone therapies, do not effectively repair bone that has already been lost. In fact, bisphosphonates have been shown to actually inhibit bone redevelopment. Many of these treatments also have serious side effects, including increasing the risk of heart di...Uncovering sex-change secrets of black sea bass
...plays the major role, he said. In males, a steroid hormone called 11-ketotestosterone is involved. The scientists are now studying those hormones as well as the enzymes that control them. By turning off estrogen production, Berlinsky says, he can turn a female fish into a male within a week. Giving 11-keto...New Research Shows Artificial Light at Night Stimulates Breast Cancer Growth in Laboratory Mice
...n breast tumors by suppressing the levels of a key hormone called melatonin. The study also showed that exten... suppresses the brain’s production of melatonin, a hormone that helps to regulate a person’s sleeping and waking cycles. The new study shows that melatonin als...Gene thwarts some pathogens, gives access to others, could save crops
...K1 protein does this by regulating a plant defense hormone called salicylic acid," he said. "The amount of salicylic acid determines the type and level of a plant's response to the pathogen. This is very important in terms of disease resistance. "In this paper, we speculate that there is an optimum level of...Possible brain hormone may unlock mystery of hibernation
The discovery of a possible hibernation hormone in the brain may unlock the mystery behind the dor.... If the findings in chipmunks are confirmed, the hormone would represent the first essential brain signal governing the seasonal adaptation, according to the...Protein found to control tumor growth in certain breast cancers
...n the pathway uncovered in breast cancer and other hormone sensitive malignancies. Those studies may help in the development of new therapeutic approaches with the potential to stabilize or even eradicate hormone-sensitive tumors." ...Evolution of 'irreducible complexity' explained
...ecular complexity ?the specific partnership of the hormone aldosterone, which regulates behavior and kidney f...ity to be activated by aldosterone long before the hormone actually evolved. Thornton's group then showed that the ancestral receptor also responded to a fa...Mutation in blood stem cells provides clues to cancer development
...m of red blood-cell production, the binding of the hormone erythropoietin (EPO) to its receptor, a process which normally regulates the production of red blood cells. As a result of this intrinsic defect, the bone marrow produces excessive numbers of red blood cells. "This discovery is important because if...Just the expectation of a mirthful laughter experience boosts endorphins 27 percent, HGH 87 percent
...ce between the two groups in terms of human growth hormone (HGH) and beta-endorphin blood levels was maintained from just prior to the beginning of video watching, throughout the hour of viewing and afterwards, also. "We believe the results suggest that the anticipation of a humor/laughter eustress (positi...UC San Diego biologists solve plant growth hormone enigma
Gardeners and farmers have used the plant hormone auxin for decades, but how plants produce and distribute auxin has been a long-standing mystery. Now researchers at the University of California, San Diego have found the solution, which has valuable applications in agriculture. The study, publis...Mayo Clinic study finds two genes predict outcome for breast cancer patients
...s. More than two-thirds of all breast cancers are hormone positive, and most of these are early stage (lymph node-negative). ...Chimpanzees can transmit cultural behavior to multiple 'generations'
...secrets of memory; determine behavioral effects of hormone replacement therapy; address vision disorders; and advance knowledge about the evolutionary links between biology and behavior. ...How can identical twins be genetically different?
... protein called 11â-HSD2 that helps deactivate the hormone cortisol. This hormone is involved in the response to stress and also has anti-inflammatory effects. The discovery that 11â...High estrogen levels associated with dementia in older men
... adjusting for age and other covariates, to see if hormone levels were associated with risk of developing dementia "Levels of bioavailable testosterone were not associated with risk of cognitive decline and incident dementia," they report. "In contrast, higher levels of bioavailable estradiol were associat...The molecular mechanism of a diabetes vaccine revealed
...ltimately eliminating the production of insulin ?a hormone needed to convert sugar, starches, and other foods into energy. Several years ago, Prof. Cohen and colleagues developed a vaccine that arrests the progression of Type 1 diabetes in laboratory animals. They had discovered that a particular protein ca...How IVF could be causing genetic errors in embryos
...ated with McCune-Albright syndrome (involves bone, hormone and skin abnormalities), pseudohypoparathyroidism Ib (involves inadequate levels of calcium and excessive levels of phosphates in the blood), and GH-secreting adenomas (type of tumour). Of these, the greatest changes in gene expression were seen in...Study finds that a woman's chances of having twins can be modified by diet
...sources, especially in countries that allow growth hormone administration to cattle," said Dr. Steinman. Dr. Steinman has been studying factors that cause or contribute to twinning ever since he delivered a rare set of identical quadruplets in 1997 at LIJ Medical Center. His most recent study published in ...Gatekeeping: Penn researchers find new way to open ion channels in cell membranes
...l currents that enable nerve impulse transmission, hormone secretion, and muscle contraction and relaxation. When there are changes to the channel, such as by mutations in a channel gene, disease can result. For example, mutations in some channel genes cause cardiac arrhythmias, including a form of the letha...Computational analysis shows that plant hormones often go it alone
...titute for Biological Studies. They show that each hormone acts largely independently in the Aug. 11 issue of...ed on by multiple hormones. And when more than one hormone did initiate a similar program, such as activating genes encoding proteins called "expansins" that l...