Machinery of the 'marijuana munchies'
...egrated with signaling by the appetite-suppressing hormone leptin. The CB1 receptor is normally triggered by natural regulatory molecules, called endocannabinoids. In their studies, the researchers concentrated on the lateral hypothalamus (LH) of the brain, known to be a center of control of food intake. Th...Olfactory system detects pheromones that control reproduction
...hemicals that are involved in changing behavior or hormone secretion. According to most biology textbooks, de...o neurons in the brain that synthesize luteinizing hormone releasing hormone (LHRH). LHRH controls the onset of puberty. In females it also stimulates ovulatio...The brain is broadly wired for reproduction
...d from neurons that produce gonadotropin releasing hormone (GnRH), which is also known as luteinizing hormone releasing hormone (LHRH). These neurons regulate sexual physiology -- including onset of puberty, ov...Study shows combination of immune substances to be safe
New research has shown that the immune-stimulating hormone known as interleukin-12 (IL-12) can safely be administered with interferon, another immune-system protein, as an experimental therapy for some cancers. Normally, interferon is used alone to stimulate the immune system to attack certain cancers. Thi...Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates
...th the goal of one day using them on patients with hormone refractory prostate cancer where the current therapeutic modalities are far from adequate." These results mark the first ever example of targeted drug delivery using nanoparticle-aptamer bioconjugates. Significantly, the drug delivery was highly spe...Researchers use 'trickery' to create immune response against melanoma
...th the goal of one day using them on patients with hormone refractory prostate cancer where the current therapeutic modalities are far from adequate." These results mark the first ever example of targeted drug delivery using nanoparticle-aptamer bioconjugates. Significantly, the drug delivery was highly spe...Hormonal male contraception reversible after few months for all men
...ible. In a similar way to ovulation suppression by hormone treatment in women, sperm production can be fully ...ogestagen treatment combinations in men. With such hormone treatment, azoospermia (no sperm in ejaculate) or severe oligozoospermia (less than 3 million sperm ...Pain killer fights breast cancer by targeting key enzyme
...mones called androgens into estrogens, such as the hormone estradiol. Estrogen is a powerful mitogen ?an agent that causes cells to divide, and too much estrogen can cause cells to divide too quickly. While many women with estrogen-dependent breast cancer take aromatase inhibitors to control their disease, ...Growth hormone is made in the brain, report scientists
...ers -- from three institutions –?found that growth hormone is produced within the hippocampus, a structure de...tion. The scientists also found that more growth hormone is produced in females than in males, and more in adults. More growth hormone was also produced in r...Penguins okay with human visitors?for now
...itored the defensive head turns and the level of a hormone secreted in response to stress (plasma corticosterone) of penguins when encountering humans. "Head turns of penguins visited for 10 days were significantly lower than those of penguins visited for 5 days and were not significantly different than for...Learning and memory stimulated by gut hormone
...Yale School of Medicine have found evidence that a hormone produced in the stomach directly stimulates the hi...le and other institutes, the study showed that the hormone ghrelin, produced in the stomach and previously associated with growth hormone release and appetite,...Alcoholism, smoking and genetics among Plains American Indians
...same receptors to release dopamine, the 'pleasure' hormone in the brain's reward pathway." Enoch added that the enzyme COMT plays an important role in the breakdown of dopamine and norepinephrine in the brain, its activity varying according to a common COMT polymorphism, Val158Met. "The Met allele results ...Gene needed for butterfly transformation also key for insects like grasshoppers
...and the stubby legs." A substance called juvenile hormone is present at each step of nymph development in in...morphosis, and the researchers found that juvenile hormone correlates with the expression of the broad gene during the nymphal stage. Juvenile hormone disappea...Hyena mothers give their cubs a helpful dose of hormones
...nfluence her offspring's behavior through prenatal hormone transfer. Previously, this phenomenon had only been documented in birds. Michigan State University's Kay Holekamp, together with her colleagues, spent almost 10 years sampling androgen levels from free-ranging hyenas in Kenya. Androgens are hormones...Pleasing plant shapes explained by new computer model
...how concentrations of the fundamental plant growth hormone auxin appear at regularly-spaced intervals. This creates the striking spiral patterns of seeds observed in sunflowers, daisies, and many other plants. Other patterns, such as branching at right angles observed in lilac branching, can be also be simu...Manipulating single cell receptor alters animal behavior
...information about the means through which a single hormone can influence multiple mammalian behaviors like le... by AT1, a receptor for angiotensin, a polypeptide hormone that regulates internal equilibrium among body fluids. By using drugs to effect these neural sign...Absence of critical protein linked to infertility
...ined that C/EBPb is a critical mediator of steroid hormone responsiveness in the uterus. "This gene is expressed when the uterus is ready for embryo attachment," said co-author Indrani C. Bagchi, a professor of veterinary biosciences in the College of Veterinary Medicine at Illinois. "Its presence indicates...Team discovers possible 'universal strategy' to combat addiction
...that VTA brain cells are sensitive to serotonin, a hormone associated with learning, sleep and mood. The team discovered that PTEN acts on these serotonin receptors, increasing brain cell activity. This is the same "reward" process sparked by drugs of abuse. Armed with this knowledge, the team designed a mo...Scientists discover a genetic switch that links animal growth and cancer
...ggered to do so by an environmental cue, such as a hormone or injury. Cells possess braking mechanisms that keep them in this quiescent state. When the brakes fail, cells that should be static start growing and dividing, leading to cancer. These brakes are proteins called tumor suppressors. Working with a t...... new actor in the mammalian reproductive system, a hormone that fills a role long suspected, but until now un...rotein, or peptide, called gonadotropin-inhibitory hormone (GnIH), puts the brakes on reproduction by directly inhibiting the action of the central hormone of ...