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Mouse brain tumors mimic those in human genetic disorder

...ted. Using this mouse model, we hope to continueto hone in on more accurate diagnostic, prognostic and treatmentapproaches."Bajenaru ML, Garbow JR, Perry A, Hernandez MR, Gutmann DH. Naturalhistory of neurofibromatosis 1-associated optic nerve glioma formationin mice. Annals of Neurology, January 2005....

Bird Brains Show How Trial and Error May Contribute to Learning

...to themselves and others, and how adults learn and hone new motor skills, such as tennis. The process relies on feedback about what works and what doesn't, also called experience-dependent or performance-based learning. "That all requires paying attention to how we're doing, experimenting with different ...

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

...ys specific for cancer stem cells. These therapies hone in on what is broken in a cancer cell while leaving the healthy tissue intact. Several Jonsson Cancer Center researchers already are doing stem cell research in laboratories, and that work will be folded into the institute. * Neurological disord...

Genetic defects give the immune system the green light to attack the pancreas

...ournal Immunity, the researchers are now trying to hone in on the exact genes involved, in mice and in human patients. “The significance of this study is that we found the chromosomal regions involved and can now zero in on the precise genes,?said Diane Mathis, Ph.D., the study’s principal investigator a...

Chickadees can help humans get their bearings

...t we encounter early in life, we could broaden and hone our spatial navigation abilities," said Dr. Sturdy and Dr. Marcia Spetch, who supervised the work conducted by graduate students Emily Gray and Laurie Bloomfield. The findings also suggest the need for more research outside of lab environments, Dr. ...

A novel method to measure circadian cycles

...ep phase syndromes. They may also use this test to hone in on the genetic mechanism responsible for such conditions. Outside the realm of medicine, future genetic studies of circadian rhythm may exploit the method developed by Schibler and colleagues to explore questions about the exact relationship betwe...

'Dating agency' boosts hunt for disease genes

...tients whose anonymity is assured. The researchers hone their hypotheses in collaboration with the clinicians who are the custodians of the samples provided by patients. The new collaborators then request top quality research materials from the DNA Network's archive. "The significance of this development...

On the track of tiny larvae, a new model elucidates connections in marine ecology

...entists to field-test such predictions and thereby hone our understanding of how marine larvae disperse in the environment and influence the structure of adult populations. In their study, the researchers coupled two types of models: One model predicts the movements of "virtual" coral larvae in the Caribb...

Protein 'fingerprint' in spinal fluid could spot Alzheimer's disease

...he first to use sophisticated proteomic methods to hone in on a group of cerebrospinal fluid biomarkers that are specific to autopsy-proven Alzheimer's disease. Those postmortem tests confirmed that the panel is over 90 percent sensitive in identifying people with Alzheimer's disease," says Kelvin Lee, t...

Pheromone from mother's milk may rapidly promote learning in newborn mammals

...tial skill: the ability of newborn pups to rapidly hone their suckling instincts during the first days of life. ...

Scientists perform 'tricky' operation

... Dunne said the results would allow researchers to hone in on genes and gene families of interest, particularly those involved in drug resistance. "The completion of the genome sequence by The Institute for Genomic Research (TIGR) and subsequent annotation of the genome database has opened many avenues...

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