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Tag: "homeostasis" at biology news

Protein overexpression at heart of heart failure

...s, e.g.: the familial forms. Intracellular [Ca2+]i homeostasis is essential for normal cardiac function and integrity, and dysregulation of [Ca2+]i is a hallmark of advanced heart failure.2 The primary trigger for cardiac [Ca2+]i transients is calcium entry through the pore subunit of the voltage-dependent L-typ...

Just like us, social stress prompts hamsters to overeat, gain weight

...predictable events, causing greater alterations in homeostasis and thus increased stress," the authors wrote. "In addition, previous research suggests that unpredictable events cause greater activation in brain regions responsible for fear and anxiety in laboratory rats and reduction in immune function compared ...

Genomatix technology facilitates de novo identification of new renal disease associated genes

...can identify regulatory pathways at work in tissue homeostasis and disease processes. ...

Regenerating worms help elucidate stem cell biology

...petent to restore aged differentiated cells during homeostasis as well as missing tissues after amputation. Unlike what's been thought about piwi for some time, which is that it was required to maintain the stem cell, we think that's not happening here. The stem cells are being maintained by another mechanism...

Researchers feed tiny pills of RNA to planarians to identify genes essential for regeneration

...mportant areas of biological research: stem cells, homeostasis (tissue loss and replacement), regeneration, and d...hat separate genetic pathways for regeneration and homeostasis must exist," Sánchez Alvarado said. "It's a huge step forward for us and opens the possibility of sy...

Newly discovered genetic disease sheds light on body's water balance

...he mechanisms that the body uses to maintain fluid homeostasis -- the correct balance of fluids needed for health... of NSIAD may offer additional insights into fluid homeostasis and clinical disease, as well as expand our understanding of GPCR signaling." The group is now cond...

Iron exporter revealed that may explain common human disorder

...n patients with the disease, perturbations in iron homeostasis result from a failure to control iron export through ferroportin, leading to increased iron release from macrophages and enhanced intestinal absorption. Indeed, patients with the disease exhibit a deficiency of hepcidin, a hormone that binds ferropor...

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