Scientists stop autoimmune disease without shutting off immune system
...ause their immune system attacks the proteins that hold skin cells together. They develop severe blisters and raw sores as the top layer of their skin falls apart, leaving them extremely vulnerable to infection. The development of drugs that completely suppress the immune system offered a lifeline to p...New approach to vaccine development provides potent, long-lasting immunity
...ask. Fourteen healthy human subjects were asked to hold onto a robot-controlled joystick and keep it from moving as the robot driver pushed repeatedly - in quick pulses - to one side. The joystick then pushed repeatedly in the opposite direction and again the subjects were asked to keep the joystick cente...Robotic joystick reveals how brain controls movement
...ask. Fourteen healthy human subjects were asked to hold onto a robot-controlled joystick and keep it from moving as the robot driver pushed repeatedly - in quick pulses - to one side. The joystick then pushed repeatedly in the opposite direction and again the subjects were asked to keep the joystick cente...Bones hold the key to blood renewal
...urturing' substances in the niche that attract and hold the stem cells to that spot, thus allowing more stem cells into the bloodstream. The team carried out their research on mice, including some developed in the lab of Prof. Ari Elson of the Molecular Genetics Department, in which the osteoclasts car...How plants avoid feeling the burn
... of the biomolecule while measuring its ability to hold a current. By holding a carotenoid under potenti...act that technically, for the first time, we could hold a molecule in a state pretty close to the natural conditions found in the plant," said Fisher. To ...Survival of the selfless - scientists find cheats don't always prosper
...ve from the sugar. This enables the cooperators to hold their own, meaning that the two different strains could coexist over the long-term without either being excluded. Lead researcher Dr Craig MacLean of Imperial College London says: "This evidence that a cooperative group can resist invasion by exploi...Ultrasound may help regrow teeth
...le," said El-Bialy. "Before this, a patient has to hold the ultrasound for 20 minutes a day for a year and that is a lot to ask." The researchers are currently working on turning their prototype into a market-ready model and expect the device to be ready for the public within next two years. ...U of MN uses robotic surgery techniques in cardiac cell therapy research
... Subsequent MRI studies showed that the cells took hold in the heart and function improved. The team used a combination of skeletal myoblasts, or cells that give rise to muscle, and bone-marrow derived cells. Both cell types have been shown to improve the development of new blood vessels and to improve ...Even fish don't swim well when they're young!
...ages: the fish power forward in a 'burst' and then hold their body straight to 'coast'. Dr Müller and her colleagues might have found what it is that prevents larvae of the zebrafish from reaching top speeds: the larvae cannot maintain their body in a horizontal position while coasting. The research team ...Researches discover gene critical for protection against septic-shock-induced death
...ssue of the Journal of Clinical Investigation, may hold potential for the treatment of life-threatening sepsis. Sepsis is a complex disease characterized by an increased inflammatory response in the body's attempt to combat an infection from microorganisms such as bacteria, fungi or viruses. A weak host ...Mystery solved: Gold's power against autoimmune diseases defined
...utoimmune diseases. MHC class II proteins normally hold pieces of invading bacteria and virus on the surface of specialized antigen presentation cells. Presentation of these pieces alerts other specialized recognition cells of the immune system called lymphocytes, which starts the normal immune response. ...Common molecular 'signature' identified in solid tumors
...tic pathways that become scrambled as cancer takes hold and spreads. He says narrowing the list of the most active ones provides a guide to directing future research. "We know that there are hundreds of miRNAs, and some of them may have multiple gene targets. Finding the ones that appear over and over a...Proteins stop blood-vessel and tumor growth in mice
...pable of producing the fibulins' effects, it would hold more promise as a viable therapy. ...New weapon in battle against osteoporosis
...xperiments on mice without ovaries. The findings hold out hope for women with a CB2 defect, too. First, it is easy to identify whether a woman is carrying the relevant mutation, so the results promise improved and faster diagnosis. Second, they have drawn attention to a previously unknown regulatory mec...HIV vaccine takes different tack to boosting immune response
...isappointing, but Chen says his laboratory results hold promise to make current HIV vaccines work better. SOCS1 was found to be part of a pathway that not only controls the production of compounds (cytokines) that stimulate inflammation but also plays a critical role in regulating the potency of anti-HIV ...Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure
...their rhythm. Should such characteristic patterns hold in patients, physicians could potentially use them to identify those people for whom defibrillators are more likely to worsen abnormal heart rate, Bursac said. So-called implantable cardioverter defibrillators (ICD) monitor the timing of heartbeats...Don't hold your breath: Carp can manage without oxygen for months
How long can you hold your breath? Scientists at the University of Oslo have recently discovered how the Crucian Carp, a close relative of the goldfish, is able to live for months without oxygen. The researchers hope that understanding how some animals cope with a lack of...UF scientists trace origin of shark's electric sense
...tors of the lateral line system. I think this will hold true and is a very important finding. But I'm skeptical about the claim the neural crest gives rise to electroreceptors. It still requires a definitive experiment, where the developing neural crest cells are marked with dye, the embryo develops and t...The diversity of marine life in the Gulf of Maine region is much greater than previously thought
...in). Most are tiny. One teaspoon of seawater can hold more than a million phytoplankton (tiny plants that float with currents). Phytoplankton also are the species that give otherwise blue oceans (reflecting the color of the sky) their varying colors. Two of the microscopic plant species are of the ge...