Nanotechnology to provide portable genetic risk detection
... test high risk groups such as women with a family history of breast cancer. To detect genetic mutations the OPTONANOGEN system uses an array of 20 microcantilevers coated in nucleic acid that react when they come into contact with a DNA sample displaying the genetic anomaly. The sample is injected into the...DNA traces evolution of extinct sabertooths and the American cheetah-like cat
...) survive in the Americas today. The evolutionary history of the extinct American cats has been closely studied by palaeontologists, but it has been difficult to determine the exact relationships of several groups. In the work reported this week, researchers created an updated family tree for the ancient ca...Genetic variation alters response to common anti-clotting drug
...on about a patient's sex, age, weight, and medical history to set the initial warfarin dose. However, it can take several months of clinic visits and needle pricks to determine an individual's ideal dose. Scientists know that variations in a gene encoding the CYP2C9 enzyme that metabolizes warfarin account f...Infectious disease expert warns of spread of Rocky Mountain spotted fever
... infected ticks. Four of the patients had a recent history of tick bite. Tests of the dogs' blood confirmed their infection with the spotted fever bacterium. Feral dogs and brown dog ticks are not a species found naturally in the Arizona region, but were introduced to the state as domesticated dogs that mov...Scientists find evidence of catastrophic sand avalanches, sea level changes in Gulf of Mexico
...ut their health, eating habits, physical activity, history of prescription medication use and tobacco, alcohol and drug consumption. The researchers also drew blood samples from each participant in order to analyze and compare similarities and differences in the epigenome. Results from the blood tests ?and...Identical twins may have more differences than meet the eye
...ut their health, eating habits, physical activity, history of prescription medication use and tobacco, alcohol and drug consumption. The researchers also drew blood samples from each participant in order to analyze and compare similarities and differences in the epigenome. Results from the blood tests ?and...Evolution of life on Earth may hold key to finding life in outer space
...mall number of groups in the nation working on the history and evolution of the core ribosomal machinery, Fox and his team of scientists focus on comparing the sequences and 3-D shapes of biological molecules. Their research benefits greatly from the many ongoing genome sequencing projects. "We do a lot of ...Protein amplification in melanoma is possible drug target
...d relatives with TACI or IgA deficiency reported a history of recurrent infections and were found to have low levels of immunoglobulin A (IgA), immunoglobulin G (IgG) or both. TACI mutations interfere with two aspects of the immune response that involve maturation of B cells, the white blood cells that make...Gene for immune deficiency syndromes found
...d relatives with TACI or IgA deficiency reported a history of recurrent infections and were found to have low levels of immunoglobulin A (IgA), immunoglobulin G (IgG) or both. TACI mutations interfere with two aspects of the immune response that involve maturation of B cells, the white blood cells that make...Huntington's cure in flies lays groundwork for broader treatment approaches
...but it's most certainly worth a shot. "I think the history of scientific discovery teaches us that we can't predict anything. So we just have to play all the cards we can possibly play." ...Secret sex life of killer fungus?
...indicate that the fungus has a recent evolutionary history of sexual activity and might still be having sex, if thus far unseen by human eyes. These results are important because if the fungus does reproduce sexually as part of its life cycle, it might evolve more rapidly to become resistant to antifungal dr...U-M researchers identify new blood test for prostate cancer
...ior to surgery, and from 159 control males with no history of cancer. They began by testing the samples again... most men. For men over 40 years old with a family history of prostate disease or for African-American men over 40 years old, some doctors suggest that a level...Insight into our sight: A new view on the evolution of the eye lens
...ted this week in Current Biology, the evolutionary history of a critical eye protein has revealed a previously unrecognized relationship between certain components of vertebrate eyes and those of the more primitive light-sensing systems of invertebrates. The findings help clarify our conceptual framework for...Proposal would allow wild animals to roam North America
...), advocating the establishment of vast ecological history parks with large mammals, mostly from Africa, that are close relatives or counterparts to extinct Pleistocene-period animals that once roamed the Great Plains. The plan, which is called Pleistocene rewilding and is intended to be a proactive approac...New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
...sk for developing type 1 diabetes, based on family history and antibody testing. At present, the trial is enrolling only at-risk individuals who have already been risk stratified. Qualified individuals interested in more information about this trial should contact Jason Gaglia at Joslin Diabetes Center at 61...Past droughts geographically widespread in the West, according to tree-ring data
...this month, will take a closer look at more recent history when scientists from the tree-ring lab will re-core trees in the Salt and Verde watersheds to gather new data from the last 40 years, a period when the watersheds have experienced both record wet and record dry episodes. The findings of the second ph...Secrets of the deep may hold key to life on other planets
... deep-sea communities could reveal an evolutionary history different to anything else on earth and even give ...tinctions or climate change. "Their evolutionary history is likely to be radically different to other, photosynthesis-based communities ?they may even mirror...Public collections of DNA and RNA sequence reach 100 gigabases
...itute, says "This is an important milestone in the history of the nucleotide sequence databases. From the first EMBL Data Library entry made available in 1982 to today's provision of over 55 million sequence entries from at least 200,000 different organisms, these resources have anticipated the needs of mole...New Scripps Oceanography project to study sediments and ecosystem restoration in Venice lagoon
...rt is being part of history." "Scripps has a long history of collaboration with the scientists and citizens ...on. This is a wonderful opportunity to extend this history into important studies of biological and toxicological implications of major public works in Venice ......e becoming useful for elucidating the evolutionary history and organization of our own genome," he explains. "Such studies are particularly informative within human pericentromeric regions ?areas of rapid change in genomic structure." Pericentromeric regions are sequences of DNA that lie in close proximity ...