Woven scaffolds could improve cartilage repair
...irst joints to be treated this way would likely be hips and shoulders, though the approach should work for cartilage damage in any joint." The researchers reported the new technology in the February 2007 issue of the journal Nature Materials. The research was supported by the National Institutes of Hea...Matrilin-3 gene discovered to prevent onset of osteoarthritis
...akdown in cartilage, commonly affecting the knees, hips and lower back. While younger people can develop osteoarthritis from joint injuries, the disease most often occurs in people over 65. The causes of osteoarthritis are not known, but they are believed to be both genetic and environmental ?such as bein...Research identifies protein in mice that regulates bone formation
...h of patients with osteoporosis who fracture their hips will die within a year. As the baby boomer generation gets older, it is predicted that the number of hip fractures may triple by 2020 unless better prevention and treatment for the disease is improved. The researchers, led by Dallas Jones, a resear...Ancient DNA helps UF researchers unearth potential hemophilia therapy
...c for them is they bleed into their joints, knees, hips and ankles, which limits their mobility." Although hemophiliac mice don't develop some of these more extreme symptoms of the disease, gene therapy prevented profuse bleeding in the animals, the findings show. More than 18,000 Americans, nearly all...Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy
...e and weakness to muscles, particularly around the hips and shoulders--hence the name "limb girdle"-- as well as in the heart. Like humans, hamsters with this particular delta-sarcoglycan gene defect have severe muscle wasting and weakness and significantly shortened lifespans due to cardiac and respirato...