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Identified main genetic variants involved in response to HIV

...needed. Nevertheless, HLA-B variation presents the highest correlation with the immune response described until now. Obtained information will be very useful in the long road to a more rational vaccine development. This and similar studies should push us toward more personalised medicine, where the most su...

Blood test may help signal tumor's remission, return in throat cancer patients

... with an increase in three or more factors were at highest risk for dying of throat cancer—more than twice as likely as patients with an increase in two or fewer factors. Finally, patients with the sharpest rises in protein levels had lower chances for survival, with patients who had a history of smoking exp...

Caribbean frogs started with a single, ancient voyage on a raft from South America

...phibians found that the Caribbean Islands have the highest proportion of amphibian species threatened with extinction. Hedges and coauthor William Duellman, a professor emeritus of the University of Kansas, were involved in much of the field work. A third co-author of the study is Penn State graduate stude...

Study shows lizard moms dress their children for success

... back patterns had a clear survival advantage. The highest survival rates were seen in the induced progeny ty...be the progeny that weren't tweaked would have the highest fitness. If these same estradiol-induced types had the highest survival rates in all years, there wo...

Research finds that circadian rhythms dominate all life functions

... with different amplitude -- the swing between the highest and the lowest point. Genes are expressed at very different levels, but most of them have the same relative change throughout the day. However, some genes show significant change in the amplitude in different organs or in response to a changing envir...

Madagascan tropical forests return thanks to better management and well-defined ownership

...g the period 1993-2000. These dry forests have the highest level of plant endemism (species found only in a p...reviously thought. "We were surprised to find the highest deforestation rates in an area with low human population density and large distance to markets, whil...

Premature births may be linked to seasonal levels of pesticides and nitrates in surface water

...es and nitrates measurements in surface water were highest (April-July) and were lowest when nitrates and pes...2.03% in June to a low of 10.44% in September. The highest rate of prematurity occurred in May-June (11.91%) and the lowest for Aug-Sept (10.79%) regardless of...

WHO data confirms low level of resistance to Tamiflu

...al Tamiflu use in Japan (35 million patients), the highest use in any market. This level of resistance is extremely low compared to rates of 65% seen in Japan with another antiviral, amantadine2. "These results confirm that the potential for the development of resistance to Tamiflu is very low, even when...

Rare soft-shell turtle, nesting ground found in Cambodia

...Our survey work to date has documented some of the highest freshwater biodiversity values in the entire Lower Mekong Basin,?said Mark Bezuijen of WWF’s Living Mekong Program, who led the team. “We discovered an entirely new plant species, Amorphophallus Sp., along with surviving populations of such threatene...

Brain maps online

...r for Neuroscience. BrainMaps.org features the highest resolution whole-brain atlases ever constructed, with over 50 terabytes of brain image data directly accessible online. Users can explore the brains of humans and a variety of other species at an unprecedented level of detail, from a broad view of th...

Risk of HIV transmission highest early in infection

... suggests that the risk of HIV transmission may be highest in the early stages of infection. According to a study published in the April 1 issue of The Journal of Infectious Diseases, now available online, early infection accounted for nearly half of all transmission occurrences in an HIV-infected populatio...

Female chimps keep the bullies at bay

...a fool-proof way to ensure they mate with only the highest ranking males, namely those with important social and physical characteristics that their offspring may inherit, according to a new study by Akiko Matsumoto-Oda from the Department of Welfare and Culture at Okinawa University in Japan. Female chimpa...

Study calculates patient time costs associated with cancer care

...the average length of time for hospitalization was highest for patients with gastric and ovarian cancers (21....for melanoma ($271) and prostate cancer ($842) and highest for gastric ($5,348) and ovarian ($5,605) cancer. In the last year of life, hospitalization time w...

Scientists find hormone activity explains adolescent mood swings

...delta subunit, such as alpha4-beta2-delta, has the highest sensitivity to steroids. In order to study its role in puberty, the researchers used a mouse model that reliably predicts the human condition. In this rodent model, the alpha4-beta2-delta receptor normally has very low expression, but increases drama...

Africa's first large-scale HIV vaccine study launches

...stone of this vaccine trial is a commitment to the highest level of preventive care for all participants. To meet this commitment, all participants will receive extensive, state-of-the-art risk-reduction counseling on a regular basis throughout the study, and high-quality male and female condoms will be prov...

Shedding new light on proteorhodopsin

...ht-driven and respiratory proton currents. At the highest azide concentrations, the average cell velocity increased 70-percent upon green light illumination. In the control study, normal E. coli cells, which do not not express proteorhodopsin, had no response to the green light. The next step in this work...

Mailman School of Public Health researchers report blood DNA can be early predictor of liver cancer

...th the development of HCC. While HCC incidence is highest in East Asia and Sub-Saharan Africa, it is also increasing in the U.S primarily as a result of HCV infection. “We are not only very excited about what this means in terms of early detection for hepatocellular cancer but optimistic about how it co...

Phthalates now linked to fat, related health risks

...ation with abdominal obesity. Indeed, men with the highest levels of phthalates in their urine had more belly fat and insulin resistance. Researchers adjusted for other factors that could influence the results, such as the mens?age, race, food intake, physical activity levels and smoking. The phthalate f...

Are journal rankings distorting science?

...ific fields that produce research published in the highest impact factor journals, causing substantial damage to the clinical research base. In an accompanying article, two researchers discuss whether impact factors should be ditched. Gareth Williams of Bristol University believes that the academic com...

Inflammation may play role in metastasis of prostate cancer

...uclear IKKa, whereas late-stage tumors contain the highest levels of active nuclear IKKa. The researchers also found a striking elevation in expression of RANK ligand in late tumors, but it was not expressed by the cancer cells. Instead, it is expressed by invading inflammatory cells. Interference with RA...

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