high 2 9

Tag: "high" at biology news

Pair of cancer genes found to drive both cell migration and division

... halves are like migrating cells - PIP3 levels are high on the sides that represent the 'fronts' of what will be two new cells, and they are low at the furrow, or what amounts to the back of the new cells," says Devreotes. In their experiments, cells without PTEN and PI3K couldn't regulate levels of PIP3...

Second messenger NAADP shows fast, dose-related impact on satiety cycle

...reatic acinar cells, has two binding sites, one of high and one of low affinity. "Unequivocal evidence that NAADP is a crucial messenger" "Intriguingly, the plot of NAADP level versus cholecystokinin concentration was best fit with a two-site model, suggesting that both the high- and low-affinity sites ...

Sponges as drugs

...tural counterparts. Although Indonesia has a very high diversity of sponge species, and therefore a large number of biologically-active substances with pharmaceutical potential, most of the species occur in relatively low densities compared to species in temperate areas. De Voogd discovered that as a res...

Leprosy genome tells story of human migrations, French researchers report in Science

...ers because its genome is filled with an unusually high proportion of damaged, nonfunctional genes. This is probably why it grows exceedingly slowly, making it difficult for researchers to study because they can't grow it in culture. In fact, M. leprae only lives in humans and in armadillos (which might h...

Determining The Fate Of Cells In The Human Body

...issue defects. Twist1 mutations are encountered at high frequency in patients with Saethre-Chotzen Syndrome. "By studying a disease in which things go wrong at the cellular level, we gain insight into how to correct these errors," said Dr. Firulli, who also is a molecular biologist at the medical school'...

Life detection instrument passes key test on road to Mars

... do when used to test samples in Berkeley with its high bioorganic levels. That means they'll need fewer channels on the instrument that travels to Mars, and the scanner used to read out the data needn't be as elaborate. This translates into a cheaper and easier way to build instruments, but more importan...

Census of Marine Life explorers surprised by diversity, density of Arctic creatures

...ice currently one to 20 meters thick, unexpectedly high numbers and varieties of large Arctic jellies, squ...ss Earth's barren southern latitudes, broken by no high lands. Deadly to explorers, inhospitable to even the mightiest ships and scientific techniques, the...

Tamoxifen-like drug suggests new ways to selectively block estrogen

...ve than tamoxifen at preventing cancer in women at high risk. Equally important was learning how the very slight difference between tamoxifen and GW5638 altered the interactions between the estrogen receptor and other molecules that are regulated by the estrogen receptor. Estrogen, tamoxifen and GW5638 ...

NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma

...ased tumor-fighting capacity. They also received a high dose of Interleukin-2 (IL-2), a protein made by th...elated to the chemotherapy and administration of a high dose of IL-2 were easily managed. The results of this study prove that a combination of chemotherap...

Hopkins AIDS experts issue warning about global efforts to provide drug therapies

...t selection committee members. Married people with high salaries were favored over singles, working men over stay-at-home moms, churchgoers over non-believers, and parents over children. The public outcry led Life magazine to feature on its cover a picture of a child rejected for treatment, prompting the ...

Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants

...n to their breastfeeding infants in concentrations high enough to prevent infection. The second study show...hers breastfeed rather than use formula due to the high cost of formula, lack of a safe water supply, and cultural norms. Roger L. Shapiro, MD, MPH, of the...

The first impact factor for PLoS Biology ?13.9

...ed to provide biologists who support open access a high profile journal for their best research papers and to demonstrate that open-access publishing works for a selective journal that only publishes outstanding science. Thanks to support from funding agencies, librarians, open-access advocates, and the s...

Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs

...ve discovered a new mechanism by which chronically high levels of the neurotransmitter dopamine exert thei...onditions, which are characterized by persistently high levels of the brain messenger, Beaulieu said. The researchers report their findings in the July 29, ...

Ancient DNA helps clarify the origins of two extinct New World horse species

...tionary relationships: though the region undergoes high mutation rates, the patterns of mutations remain stable over thousands of generations. The mtDNA analysis of the South and North American horses provided evidence that stilt-legged horses, the Hippidion genus, and caballine, or true horses, all arose...

Does vitamin C help prevent or treat the common cold? Maybe not, after all.

...e of the seven trials, patients took a single very high dose of the vitamin (8 g) on the day their symptoms started and experienced a shorter illness compared with people who took a placebo pill. (3) The authors say that the results in this single trial are "tantalising and deserve further assessment." D...

Critical step traced in anthrax infection

...overy of the phi-clamp will prove to be one of the high points along the path to understanding how translocation occurs in this system," Collier said. One of the greatest strengths of the experiment, according to Collier, was the integrative use of technologies applied to the testing procedures. Both cel...

Team Invents Device For Weighing Individual Molecules

...quency of mechanical vibration, although at such a high pitch that the "notes" are nearly as high in frequency as microwaves. The researchers set up electronic circuitry to continually excite and m...

Random gene expression may drive HIV into hiding

...le: After a few days, all cells expressed either a high level of virus or none at all. When Weinberger to...me behavior: some turned their viral expression on high and others turned it off. This dichotomy in cell fate from genetically identical cells is consisten...

Scientists discover global pattern of big fish diversity in open oceans

...map--wrestle with how to save global fisheries and high seas diversity. "The high seas are the least protected places on this planet ?a region where legal and pirate fishers rub shou...

Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

...cent of women with ovarian cancer have tumors with high levels of active Akt," according to Sebti. "To our knowledge, this is the first Akt inhibitor headed toward clinical trials," said Jin Cheng, MD, PhD, USF Professor of Pathology and Interdisciplinary Oncology. Cheng and Sebti's study results were p...

1 2 3 4 5 6 7 8 9 10