NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
...suppressor genes (p27 and APC) and were fed a diet high in fat and low in calcium and vitamin D. "It appears that p21 activation through sulindac offers protection against both a lack of tumor suppressor genes as well as poor diet," says the lead author, WanCai Yang, M.D., an assistant professor of medic...Red delicious, Northern Spy apples have most antioxidants, chemists find
...nd texture do not matter, choosing an apple with a high proportion of polyphenols in the flesh and skin can potentially produce more health benefits,?Tsao said. “But eating any apple is better than eating no apple at all.?/p> Elsewhere, three recent studies by researchers at Cornell University in New ...Taking the piste out of Alpine vegetation
... avoidance of areas with vegetation of articularly high conservation value," they say. Some alpine ecosystems are extraordinarily rich in species, but they are also sensitive and susceptible to changes in land use and climate. ...UCLA scientists store materials in cells natural vaults
...t amounts of biomaterial. Dubbed vaults ?for their high arches reminiscent of cathedral ceilings ?these naturally occurring capsules may prove less likely to elicit an immune response than foreign carriers like viruses. IMPACT: The UCLA discovery will enable many potential applications, including: *......stem except the brain and spinal cord); abnormally high blood pressure; and proteinuria, a condition in which urine contains an abnormal amount of protein, than patients receiving paclitaxel alone. Other side effects were similar between the two treatment groups. Bevacizumab, a humanized monoclonal antib...Product improves peptide identification for proteomics research
...er for Agilent's ion trap mass spectrometers. "The high resolution, scan speed and sensitivity of the LC/M... a wide range of qualitative applications in which high performance and productivity are essential, particularly in proteomics research." "The LC/MSD Trap ...Study uncovers bacteria's worst enemy
...actinides are chemically toxic to bacteria only at high levels far, far above concentrations at contaminated sites, and that common toxic metals, such as cadmium, nickel, and chromium, are more likely to cause problems for the bacteria." Generally, bacteria used for bioremediation are selected to target ...Secret of smallpox's success may lead to bioterror cure
...n protect against mousepox in mice, then we have a high level of certainty that the vaccine will be able to protect against smallpox in humans," Jacobs said. "Since you can't test in people, the FDA's animal efficacy rule applies. If you can show efficacy in several animal models, then you can presume ef...Measles Deaths Worldwide Drop By Nearly 40% Over Five Years
...nder five years of age, especially infants, are at high risk of contracting measles and are more vulnerable to death. The vast majority of measles deaths are found in low-income countries. Each year more than 130 million children are born and "we must reach each and every one with measles vaccination," sa...Disease progression model of pancreatic cancer developed by Penn researchers
...ment. The researchers were surprised to discover a high degree of heterogeneity in expression among these key molecules across the specimens. After ruling out the likelihood that this variability resulted from additional acquired mutations in known key tumor suppressor pathways, Hingorani suggests, "there...Man-made wetland's effectiveness similar to natural marsh
...It also retained these nutrients during periods of high precipitation, such as during storms and torrential downpours, which saturated the ground. "It's encouraging that this wetland acted as an effective sink, even when runoff from fertilized fields was especially high," Mitsch said. "Of course, that co...Basis for DNA ejection from single phage particles
...expectedly complex. DNA release occurred at a very high rate, reaching 75,000 base pairs of DNA/sec, but in a stepwise fashion. Pausing times were observed during ejection, and ejection was transiently arrested at definite positions of the genome in close proximity to genetically defined physical interrup......gilent's new CGH microarray platform provides very high sensitivity, enabling researchers to detect small changes in chromosomes, including single copy deletions, which have previously been the most difficult to find," said Agilent Integrated Biology Solutions product manager David Tunks. "We hope the ou...Symbiotic bacteria protect hunting wasps from fungal infestation
...t threat to higher organisms, and because of their high reproductive potential and adaptability, they are extremely difficult to control. Ironically, the best counteragents against microbes are often other microbes that produce very potent antibiotics. Thus, an effective and elegant way to counter the thr...Finding hidden invaders in a Hawaiian rain forest
...le the invading Canary Islands tree has relatively high nitrogen concentration (1.5% to 1.8%), because it can acquire nitrogen from the atmosphere. "The high leaf nitrogen associated with the invading tree means that it is basically fertilizing the forest wi...Unchecked DNA replication drives earliest steps toward cancer
...netically unstable, whether they have an unusually high mutation rate. What we show in this study is that they do have a higher mutation rate than normal through this mechanism." Fortunately, cells have an effective on-board damage control system, managed by the p53 gene. A protein called 53BP1, the crit...Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX
...s will significantly improve the ability to obtain high quality profiles from blood, thus enabling clinical research and collecting samples for multi-site clinical trials." About PreAnalytiX GmbH: The purpose of PreAnalytiX GmbH, a Swiss-based joint venture between BD (Becton, Dickinson and Company) and...A New Species of Monkey is Discovered in Tanzania: The First in Africa for More Than 20 Years
... 'honk-bark' by the authors. The monkeys occur as high as 8,000 ft (2450 m) where temperatures frequently drop below freezing; its long coat is probably an adaptation to the cold. The taxonomic name of the species, Lophocebus kipunji, recognizes the monkey’s local Kinyakyusa name (pronounced kip-oon-jee)...Breakthrough isolating embryo-quality stem cells from blood
...st enough for industrial separation of millions of high grade stem cells, but it promises a realistic alternative to embryo use if it can be scaled up. Meanwhile, it is already being used to isolate low-grade stem cells which can develop into skin. In collaboration with medical professionals in Leipzig, e......gestion. This delay is good because it reduces the high peaks of glucose, which otherwise would require th...mparable dosage we use in rats is probably way too high for humans," he added. The 'South Beach' inference; speculation about HCA's potential in diabetes ...