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Tag: "high" at biology news

Solution to Pollution: New Bacteria Eats Toxic Waste

...id student and faculty interest in this project is high because of its human-interest orientation. In Orson Wells?classic tale “War of the Worlds,?invisible bacteria saved the world as well as the people in it. Through this project, life is imitating art and through these unique bacteria the world may st...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...taining the muscle-restricted gene, mice exhibited high levels of the enzyme and reduced glycogen content in the injected muscle. The mice also had a reduced immune response to the new enzyme, compared to those in which gene expression was not limited to muscle, they found. Moreover, intravenous administ...

Scientists decipher genome of fungus that can cause life-threatening infections

... the opposite strand. Researchersalso identified a high percentage of transposons (moveable elements)within the genome, which may account for the genome rearrangementsoften observed between different Cryptococcus isolates.TIGR's Fraser says the Cryptococcus genome sequence will benefit a widerange of biom...

Needling Chromosomes Reveals Cell Division Secret

...To study chromatid adhesion, Paliulis mastered the high art ofmanipulating two infinitesimal glass needles to impale each of twosister chromatids in cultured grasshopper cells at the appropriate timein cell division. Then, she would ever-so-gently apply force to pullthem apart. Upon release, if they remai...

Researchers identify target for cancer drugs

...gulation of cell division and survival. Abnormally high activation of Akt has long been implicated in a variety of cancers. If Akt travels to the cell membrane, it is switched on and promotes cell division, often contributing to tumor growth as a result. However, as long as it stays within the cell cytopl...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

... small increase in clathrin kicks endocytosis into high gear." The study was conducted in fibroblasts, a kind of cell used in many cell-culture experiments. But Dr. Ryan said the findings have broad implications for cells throughout the body, including those closely tied to brain disorders, cardiac illne...

Probing The Promise And Perils Of Nanoparticles

...vering drugs to their targets inside the body, but high concentrations of these nanoparticles can be toxic...membranes, making the membranes more permeable. At high enough concentrations, they can completely destroy the membranes, killing cells in the process. But ...

Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer

...c cells, and infects them. Inside,VRP-neu produces high levels of the HER2/neu protein, which thedendritic cells then display on the outside of their cell surface. Thisis, in fact, a neat trick, says Lachman, because the function ofdendritic cells is to flag the immune system by presenting “antigen,?or pi...

Highly adaptable genome in gut bacterium key to intestinal health

...ively shifts more than a quarter of its genes into high gear when its host's diet changes from sugar to co... bacteria, with B. theta. The mice were fed a diet high in complex carbohydrates and low in simple sugars. Ten days later, the activity of all genes in the ...

Amino acids in nectar enhance butterfly fecundity: A long awaited link

...wn that butterflies actually prefer nectars with a high amino acid content. These findings led to speculations about the significance of nectar amino acids for butterfly fitness and insinuated that butterflies have acted as agents of natural selection on nectar composition. In order to determine whether...

A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020

...c cells, and infects them. Inside,VRP-neu produces high levels of the HER2/neu protein, which thedendritic cells then display on the outside of their cell surface. Thisis, in fact, a neat trick, says Lachman, because the function ofdendritic cells is to flag the immune system by presenting “antigen,?or pi...

Researchers add new tool to tumor-treatment arsenal

...lls can continue to multiply. The dilemma is that high doses of DNA-damaging agents can be toxic, and doses that are too low allow for DNA repair and further cell growth. Thus, says Dr. Thomas, there is need for drugs that can sensitize cells to lower doses of DNA-damaging agents to guarantee cell death,...

Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers

...ver, it continues to breathe in oxygen at the same high volume it uses while flying. The result is excess ...or only a very short time. In a stream of air with high oxygen on the other hand, the respiratory system opens briefly and then closes firmly for a long tim...

Scientists discover unique microbe in California's largest lake

...rovided anutrient-rich environment with relatively high amounts of infraredlight; in the Salton Sea, the w...ves create a comparableniche. Wood thinks that the high availability of nutrients in thewaters of the Salton Sea is what allowed the microbe to survive with...

Potential Cure for Lymphoma in HIV patients

...edindividuals remains challenging, due to both the high incidence ofrefractory disease and the high risk of treatment-relatedcomplications. The ability of high dose chemotherapy as demonstrated inthis...

An entropy-based gene selection method for cancer classification using microarray data

...are able to classify various cancer sub-types with high accuracy. In addition, the feature set obtained is very compact, that is, the redundancy between genes is reduced to a large extent. This implies that classifiers can be built with a smaller subset of genes. ...

NYC's First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention

...S care providers see many cases of patients with a high degree of some drug resistance; however, doctors and providers can usually find a second or third line drug therapy regimen for effective treatment. This man's strain of infection appears to be much more pathogenic, much more able to wreak havoc with...

Nano-Probes Allow an Inside Look at Cell Nuclei

...n, quantum dots fluoresce for days at a resolution high enough to detect biological events carried out by ...ent proteins only fluoresce for a few minutes at a high resolution. These labels are also either toxic to cells or difficult to construct and manipulate. I...

Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation

...owing army of these immune cells. This proves that high levels of sjTREC in blood means that a large numbe...population. "This is the first demonstration that high levels of sjTREC in a potential stem cell recipient can predict that their thymus will successfully ...

Ice core 'dipstick' indicates West Antarctic ice has thinned less than believed

...n that, in the ice age, glacial ice built to quite high elevations in the mountains just inland from the Ross Ice Shelf. That led to the expectation that Siple Dome had to be substantially thicker than it is now as the ice moved from the mountains to the ice shelf. But the new study shows the ice could no...

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