Fragile US vaccine system needs improvement despite dramatic gains in health over past century
... levels of vaccine-preventable diseases and record high levels of immunizations among children. According to the article, however, problems with vaccine supply, cost and safety threaten to derail the vaccine successes of past decades, and the system faces additional challenges posed by the adult immunizat...Excess liver gene protects against high-fat diet
...excess of liver X receptor (LXRa), when fed a diet high in fat, remained free from the high cholesterol and blood vessel plaques exhibited by animals with the normal complement of receptors. R...Open Access journals get impressive impact factors
...ove that BioMed Central's Open Access journals are high quality and widely read and cited. Journals publis...ive titles in the top five of their specialty. The high impact factors for these journals affirm that they are respected by researchers, and are fast becomi...'Bionic' arm gives amputee sense of touch
...ove that BioMed Central's Open Access journals are high quality and widely read and cited. Journals publis...ive titles in the top five of their specialty. The high impact factors for these journals affirm that they are respected by researchers, and are fast becomi...Mosaic mouse technique offers a powerful new tool to study diseases and genetics
... subset of cells and study gene function at a very high resolution," says Luo, who also is affiliated with the Neuroscience Institute at the Stanford School of Medicine. "Our method can be used to study a variety of tissues, such as the skin, heart and nervous system." Green glow Mosaics are designed to...Study: Well-known protein helps stem cells become secretory cells
...ere turned on when. All 34 genes were expressed at high levels in the early salivary gland, they found. Ac...r involved in keeping secretory genes expressed at high levels, and Fork head acts through it," said Andrew. CrebA's role in the fruit fly's epidermis give...It's electric: Cows show promise as powerplants
...microbial fuel cell. Each chamber was about a foot high and about 6 inches in diameter. The chambers were separated by a special material that allowed protons to move from the negative (anode) chamber into the positive (cathode) chamber. This movement of protons, along with the movement of electrons acro...Scientists take aim at virulent bacteria by decoding machinery of key control enzyme
...g structure-based virtual screening techniques and high throughput equipment to screen for potential inhibitor compounds against the Dam enzyme. ......xpression most frequently correlated with areas of high inflammation. The authors also examined whether inflammatory cytokines were produced in primary cartilage and synovial cells from arthritic versus normal joints. While OA cells did not differ from controls, primary RA cells produced TNF-a, IL-1ß and...Motor transport in bio-nano systems
...ts a genuine phase transition from a low flux to a high flux state. Likewise, regular patterns of filaments have been shown to lead to enhanced motor diffusion along the substrate surface. All of these results have been obtained from a combination of analytical calculations and computer simulations. Thes...Deep sea algae connect ancient climate, carbon dioxide and vegetation
...tter understanding of Earth's climate system under high greenhouse gas conditions." The findings were based on calibration of carbon-containing compounds produced by ancient sea surface algae that were recently isolated in deep sea drill cores. The data indicates that between 45 - 34 million years ago th...New Vaccine To Be Used For First Time In Polio Outbreak Response
...rates that outbreaks can be quickly contained with high quality immunization campaigns which reach every c...e polio transmission is re-established. Concern is high that the ongoing outbreak of polio in Africa might lead to re-infection of more countries in the pol...Invasive parasite destroying fish species
...tter understanding of Earth's climate system under high greenhouse gas conditions." The findings were based on calibration of carbon-containing compounds produced by ancient sea surface algae that were recently isolated in deep sea drill cores. The data indicates that between 45 - 34 million years ago th...First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
...ssentially any size and complexity while achieving high levels of protein expression. Moreover, it is the only technology to date that restricts deposition of the therapeutic protein to egg white." "Monoclonal antibodies have demonstrated great success as human therapeutics, with over 25 approved for hum...Stem cells grown in lab mirror normal developmental steps
...tter understanding of Earth's climate system under high greenhouse gas conditions." The findings were based on calibration of carbon-containing compounds produced by ancient sea surface algae that were recently isolated in deep sea drill cores. The data indicates that between 45 - 34 million years ago th...Anthrax test, developed by army and CDC, receives FDA approval
...aluate the assay performance. This work has set a high bar for other tests to meet." USAMRIID scientists standardized and validated the test to make it more rugged, more reproducible across laboratories, and more resistant to user error. They developed a clearly defined method for production of gamma ...Scripps research scientists solve structure of a critical innate immune system protein
...anning proteins are rich in repeats that contain a high percentage of the amino acid leucine. This fact was important to Wilson and his colleagues because the leucine-rich proteins are often decorated with sugars (glycans), and fall into the class of biological molecules known as "glycoproteins." "Amazin...'Mad cow' proteins successfully detected in blood
...aluate the assay performance. This work has set a high bar for other tests to meet." USAMRIID scientists standardized and validated the test to make it more rugged, more reproducible across laboratories, and more resistant to user error. They developed a clearly defined method for production of gamma ...Discovery of an American salamander where it shouldn't be: Korea
... in the most surprising way, when some guy who's a high school teacher from Illinois goes out with his class and says, 'Let's look for salamanders, let's see what we can find when we turn over rocks and logs.'" To date, the salamander has been found in 16 locations in three Korean provinces, and Wake and...Scalpel-free surgery could reduce risk of HIV and hepatitis exposure for health care workers
...y 2005 issue of the Annals of Surgery. "Given the high incidence of these infections, however, we have developed new strategies such as 'sharpless' surgery-a surgical technique which uses high-technology alternatives to needles and knives. We advocate using these techniques whenever possible in high-risk...