Darkness unveils vital metabolic fuel switch between sugar and fat
...ark. Why not darkness as a switch?" Mice do not hibernate but they can slip into a similar short-term state of torpor. Lee and colleagues started with a microarray analysis of gene expression in the livers of mice subject to the usual light-dark cycle and those kept in the dark for 48 hours. One gene fi...Possible brain hormone may unlock mystery of hibernation
...iological phenomena in mammals is their ability to hibernate circannually, which allows them to survive unusually low body temperatures at or near freezing," said study author Takashi Ohtsu of Kanagawa Academy of Science and Technology in Japan. Scientists have attempted for decades to identify substances resp...Breaks in hibernation help fight bugs
...r if they are infected," says Luis. If the animals hibernate for long they risk serious infection, she says, while waking up frequently wastes precious energy, and could prove fatal as well. In other words, animals with an optimal time of torpor will win out over others, says Luis, who presented her findi...What animals can tell us about hemorrhage, organ transplants and aging
...time in the mountains studying bears, animals that hibernate for months without suffering significant muscle atrophy They follow migrating birds thousands of miles to understand how they fuel their metabolisms for grueling transoceanic flights They slog through wetlands, studying frogs that literally freeze ...Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...s to act out its stealth attacks is its ability to hibernate when times are hard by forming dormant spores. More than 110 of its set of almost 3700 genes are used to control spore formation and germination when opportunity arises. "C. botulinum shows us one extreme of the ways that bacteria can make th...