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Tag: "hereditary" at biology news

Researchers discover inherited mutation for leukemia

...rst time a gene that appears to be associated with hereditary CLL," says coauthor John C. Byrd, professor of int...ho also develop the disease – strong evidence of a hereditary predisposition. However, usually only two or three people within a family are affected, making it di...

Researchers attach genes to minichromosomes in maize

...t carry genes and functions in the transmission of hereditary information. Whereas a chromosome is made of both centromeres and telomeres with much intervening DNA, a minichromosome contains only centromeres and telomeres, the end section of a chromosome, with little else. However, minichromosomes have the abil...

Study examines risk of soft tissue sarcomas in hereditary retinoblastoma survivors

... National Cancer Institute quantifies the risk of hereditary retinoblastoma survivors developing specific subty...ve 5 years after diagnosis. However, patients with hereditary retinoblastoma are at a high risk of developing another cancer, including soft tissue sarcomas. The ...

Technology reveals 'lock and key' proteins behind diseases

...en disabled by mutation, causes cystic fibrosis, a hereditary disease that results in progressive disability and early death. Another important ABC protein is the Multidrug Resistance Protein (MRP), which normally removes drug metabolites and toxins from cells in our bodies but when overzealous can contribute t...

MU researcher placing eye implants in cats to help humans see

...t one in 3,500 people worldwide is affected with a hereditary disease, retinitis pigmentosa, that causes the dea...Abyssinian and Persian cats that are affected with hereditary retinal blinding disease. The cat's eye is a good model to use for this type of research because it ...

Putting an old drug to a new use

...ne of the most common genetic disorders in Europe, hereditary hemochromatosis, which affects about one in 300 Eu...pine a promising candidate for a new drug to treat hereditary hemochromatosis and other iron overload disorders." Combining electrophysiology, cell biology and...

Elucidation of the genome for diabetics with DNA chips

... These four genes may account for up to 70% of the hereditary basis of DT2. Several tens of other strong "signals" have also been identified. If confirmed, these signals may complete the diabetic genome map. This work has predictive value and has potential implications for DT2 prevention and treatment. At a ...

Napoleon's mysterious death unmasked, UT Southwestern researcher says

... his stomach, rather than a heretofore belief of a hereditary disposition to the cancer. The analysis, which also refutes rumors of arsenic poisoning, points to gastrointestinal bleeding as the likely immediate cause of death. The report, available online and in the January edition of Nature Clinical Practi...

Tiny clue reveals new path toward heart disease

... to all parts of the body. Kalirin contains the hereditary information for the production of a protein that is involved in the migration of cells from one spot to another within smooth muscle. According to the researchers, the newly identified SNP may change the level of this protein in blood vessels, causin...

New hereditary breast cancer gene discovered

A new hereditary breast cancer gene has been discovered by scientis...n. The researchers found that women with a certain hereditary deformity syndrome run a nearly twenty times higher risk of contracting breast cancer than expected....

Vaccination with embryonic stem cells prevents lung cancer in mice

...l vaccines that prevent cancers in humans, such as hereditary breast and colon cancer and lung cancer caused by smoking or other environmental factors. Professor John Eaton told a news briefing at the EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Prague today (Wednesday 8 Nov...

Embryonic selection of sex avoids conceiving blind children

...birth to a male child. Retinosis Pigmentaria is a hereditary illness of the eyes of a degenerative nature. It causes a serious reduction in visual capacity and, in many cases, leads to blindness. The ailment does not affect males and females equally: in the case of men, there is a 50% probability of suffering ...

Gene therapy for hereditary lung disease advances

...to combat alpha-1 antitrypsin deficiency, a common hereditary disorder that causes lung and liver disease, has caused no harmful effects in patients and shows signs of being effective, University of Florida researchers say. In a clinical trial, researchers evaluated the safety of using a so-called gene vector ...

Development of gene therapy

... signs of success in certain areas, such as severe hereditary immunodeficiency diseases, while in other areas there is still considerable need for research. Moreover, the clinical application of gene therapy requires careful risk/benefit assessment, although in this respect it does not differ substantially from...

Jumping gene could provide non-viral alternative for gene therapy

... insects. Sleeping Beauty has been used to correct hereditary diseases, including hemophilia, in a mouse model. For this study, researchers used transposons to deliver an antibiotic-resistant gene. "It's a way of screening and seeing which transposon is better," Dr. Kaminski says. They found that while piggy...

Embryo tests give parents the choice

...-onset diseases such as Alzheimer's, Huntington's, hereditary breast cancer, and many other cancers. PGD was originally intended to overcome infertility and to ensure that all children are born with achance of a full and flourishing life, says Eric Cohen, head of the bioethics programme at the Ethics and Publi...

Ghost protein leaves fresh tracks in the cell

...compensate for genetic lesions in diseases such as hereditary anemia, Duchenne muscular dystrophy, cardiac arrhythmia and the degenerative brain disease spinocerebellar ataxia 5. "As we learn more about mutations involving spectrin and their relationships to human diseases, we're going to have more and more q...

A new kind of mutation could explain numerous phenotypic variations in various species

...in many species ?among which humans ?including the hereditary predisposition to various diseases. Researchers a...g similar phenomena for other phenotypes including hereditary diseases. ...

Researchers attack tumor cells by exploiting dependency on sugar metabolism

...ment of cancer. "Because individuals with complete hereditary deficiency of LDH-A do not show any symptoms under ordinary circumstances, the genetic data suggest that inhibition of LDH-A activity may represent a relatively nontoxic approach to interfere with tumor growth," explains Dr. Fantin. ...

Researchers find cause of frontotemporal dementia

... Chromosome 17 is the carrier of the tau protein's hereditary code, and defects in this protein cause tau-positi...in is important for the brain cells' survival. The hereditary defects that the researchers have found in FTD patients cause only 50% of the protein to be produced...

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